公开(公告)号：PL2126555T3

公开(公告)日：2018-12-31

申请号：PL08707817

申请日：2008-02-29

Applicant: HOFFMANN LA ROCHE

Inventor： BUCK HARVEY B JR

IPC: G01N27/327 ,  A61B5/1495

公开(公告)号：CA2785704A1

公开(公告)日：2011-07-14

申请号：CA2785704

申请日：2010-12-30

Applicant: HOFFMANN LA ROCHE

Inventor： LICA GEORGETA ,  BUCK HARVEY B JR ,  GROLL HENNING

IPC: G01N33/487 ,  G01N27/22 ,  G01N33/49

Abstract: One aspect concerns a technique for detecting analyte concentrations, such as glucose concentrations, in blood or other bodily fluids. This technique utilizes an electrochemical test strip that includes a mediator system that generates a linear faradic response at relatively low applied potential differences. An alternating current excitation signal is applied to blood in the test strip. The alternating current excitation signal includes a low frequency signal and a high frequency signal that has a higher frequency than the low frequency signal. The glucose concentration is determined by measuring a low frequency response to the low frequency signal, measuring a high frequency response to the high frequency signal, estimating the glucose concentration based on the low frequency response, and correcting the glucose concentration for one or more error-causing variables based on the high frequency response.

公开(公告)号：CA2783746A1

公开(公告)日：2011-07-07

申请号：CA2783746

申请日：2010-12-23

Applicant: HOFFMANN LA ROCHE

Inventor： DIEBOLD ERIC R ,  BUCK HARVEY B JR ,  BEATY TERRY A

IPC: G01N33/49

Abstract: The present disclosure relates to various methods for measuring the amount of an analyte present in a biological fluid using an electrochemical testing process. Various embodiments are disclosed, including the use of AC test signals and the performance of tests having a Total Test Time within about 2.0 seconds or less, and/or having a clinically low Total System Error.