公开(公告)号：AU691882B2

公开(公告)日：1998-05-28

申请号：AU1766695

申请日：1995-04-26

Applicant: MEDTRONIC INC

Inventor： STEWART MARK T ,  MORRIS MARY M ,  DIDOMENICO EDWARD ,  KENNEY KENNETH W ,  HESS DOUGLAS N

IPC: A61N1/05 ,  B29C59/14 ,  H05H1/46

Abstract: An implantable electrode type lead assembly 10 of the flexible type which is particularly adapted for implantation in the cardiac tissue for applications such as use with a pacemaker. The lead assembly has an electrode head 40 which includes a fixation spiral for implantation into tissue. The spiral or rotation action of the electrode head 40 is controlled by means of an elongated torsionally wound electrical coil conductor 14, the coil extending through the lead from the proximal to the distal end thereof and carried within a silicone tube 24 which is co-extensive therewith, the tube having been especially treated to modify the slip characteristics of the internal diameter (ID) thereof for high efficiency torque transfer.

公开(公告)号：DE68919534T2

公开(公告)日：1995-04-13

申请号：DE68919534

申请日：1989-05-02

Applicant: MEDTRONIC INC

Inventor： DOAN PHONG D ,  COBIAN KENNETH E ,  UPTON JAMES E ,  HAEG DANIEL C ,  HESS DOUGLAS N ,  BASS WAYNE R ,  UFFORD KEITH A

IPC: A61N1/05

公开(公告)号：WO0249713A3

公开(公告)日：2003-02-06

申请号：PCT/US0146494

申请日：2001-11-08

Applicant: MEDTRONIC INC

Inventor： CLEMENS WILLIAM J ,  HESS DOUGLAS N ,  FREIBORG MICHAEL L

IPC: A61M25/00 ,  A61N1/05 ,  A61M25/01

CPC classification number: A61N1/056 ,  A61M25/0026 ,  A61M2025/0025 ,  A61N2001/0578

Abstract: An introducer catheter used to deliver an endocardial cardiac electrode has a stylet lumen which collapses upon removal of the stylet to allow for more clearance for the lead and connector to pass when the catheter is removed after lead placement. The collapsible stylet lumen permits the introducer catheter size to be reduced to 8 or 9 French and provide for passage of a 4 French lead.

Abstract translation: 用于输送心内膜心脏电极的导引器导管具有管心针内腔，其在移除管心针时折叠，以便当导管在导管移除后被移除时允许导管和连接器通过更多的间隙。 可折叠的探针管腔允许导引器导管尺寸减小到8或9法国，并提供4法国导线的通过。

公开(公告)号：WO02058465A9

公开(公告)日：2003-09-18

申请号：PCT/US0149226

申请日：2001-12-19

Applicant: MEDTRONIC INC

Inventor： CLEMENS WILLIAM J ,  HESS DOUGLAS N ,  SOMMERS JOHN L ,  SOYKAN ORHAN

IPC: A61N1/05

CPC classification number: A61N1/056 ,  A61N2001/0585

Abstract: A medical electrical lead (10) including an inflatable member (12) at a distal tip section, and a system of use, are disclosed. The inflation member is adapted to engage the walls of a cardiac vein or coronary artery to occlude the vessel. According to one aspect of the invention, the inflation member is formed of a bio-absorbable material. In another embodiment, the inflation member is a micro-porous material. The lead of the current invention may include a port located distal to the inflation member is in the inflated state. This allows a fluoroscopic image of a patient's vascular system to be obtained while the lead is in place within a vessel. A perfusion lumen may be provided to allow a partial flow of blood to continue around the inflation member (18) when the inflation member is occluding a vessel. In one embodiment, lead is provided with a lumen for receiving a stiffening menber such as a stylet (64) to aid in lead is placement. According to one method of using the current invention, inflation member may be inflated after the lead is placed at a desired implant site to provide a temporary fixation mechanism during withdrawal of the stiffening member and/or a guide catheter or sheath used to place the lead at the implant site. This temporary fixation mechanism may also be employed to retain a desired lead location while thresholds are obtains. The inflation member may be retained in an inflated state for a longer predetermined period of time until tissue in-growth begins to occur around the lead.

Abstract translation: 公开了一种包括在远侧末端部分处的可膨胀构件（12）和使用系统的医疗电气引线（10）。 充气构件适于接合心脏静脉或冠状动脉的壁以闭塞血管。 根据本发明的一个方面，充气构件由生物可吸收材料形成。 在另一个实施例中，充气构件是微孔材料。 本发明的引线可以包括位于充气构件远侧的端口处于充气状态。 这允许在铅在血管内就位时获得患者血管系统的透视图像。 当充气构件封闭容器时，可以提供灌注腔以允许血液部分流动在充气构件（18）周围继续。 在一个实施例中，引线设置有用于接收诸如探针（64）的加强型的管腔，以帮助引线放置。 根据使用本发明的一种方法，在引线放置在期望的植入位置之后，充气构件可以被充气，以在撤回加强构件和/或用于放置引线的引导导管或护套时提供临时固定机构 在植入部位。 也可以采用该临时固定机构来保持期望的引导位置，同时获得阈值。 膨胀构件可以保持在膨胀状态较长的预定时间段，直到在铅周围开始发生组织增长。

公开(公告)号：WO0249713B1

公开(公告)日：2003-04-24

申请号：PCT/US0146494

申请日：2001-11-08

Applicant: MEDTRONIC INC

Inventor： CLEMENS WILLIAM J ,  HESS DOUGLAS N ,  FREIBORG MICHAEL L

IPC: A61M25/00 ,  A61N1/05 ,  A61M25/01

CPC classification number: A61N1/056 ,  A61M25/0026 ,  A61M2025/0025 ,  A61N2001/0578

Abstract: An introducer catheter used to deliver an endocardial cardiac electrode has a stylet lumen which collapses upon removal of the stylet to allow for more clearance for the lead and connector to pass when the catheter is removed after lead placement. The collapsible stylet lumen permits the introducer catheter size to be reduced to 8 or 9 French and provide for passage of a 4 French lead.

Abstract translation: 用于递送心内膜心电极的导引导管具有探针导管，当探针插入导管时，探针导管在移除探针时会收缩，导线和连接器通过。 可折叠的探针管腔允许导引导管尺寸减小到8或9 French，并提供4法国导线的通过。

公开(公告)号：WO2007079375A2

公开(公告)日：2007-07-12

申请号：PCT/US2006062609

申请日：2006-12-27

Applicant: MEDTRONIC INC ,  SOMMER JOHN L ,  HESS DOUGLAS N

Inventor： SOMMER JOHN L ,  HESS DOUGLAS N

IPC: A61N1/00

CPC classification number: A61N1/0573 ,  A61N2001/0585

Abstract: An implantable medical lead configured for active fixation in the vasculature of a patient includes an elongated lead body having a central lumen and a distal tip. Disposed within the central lumen are a fixation helix and an elongated member, such as a lead coil, coupled to the fixation helix. The elongated member is adapted to rotate the fixation helix, thereby causing it to advance or retract within the central lumen of the lead body. The lead body includes a window along a portion of its length through which the fixation helix may be affixed to a blood vessel of the patient's vasculature.

Abstract translation: 被配置用于在患者的脉管系统中主动固定的可植入医疗引线包括具有中心腔和远端尖端的细长引线主体。 设置在中心腔内的是固定螺旋和连接到固定螺旋的细长构件，诸如导线圈。 细长构件适于旋转固定螺旋，从而使其在引线主体的中心腔内前进或后退。 导联体包括沿着其长度的一部分的窗口，固定螺旋可通过该窗口固定到患者脉管系统的血管。

公开(公告)号：WO03030988A2

公开(公告)日：2003-04-17

申请号：PCT/US0233662

申请日：2002-10-07

Applicant: MEDTRONIC INC

Inventor： ALINDER JASON ,  CASAVANT DAVID A ,  HESS DOUGLAS N ,  GRENZ DAVID A ,  FREIBORG MIKE ,  CLEMENS WILLIAM J ,  RUFF MICHAEL A

IPC: A61N1/05 ,  A61N1/00

CPC classification number: A61N1/0573

Abstract: Methods and endocardial screw-in leads for enabling provision of electrical stimulation to the heart, particularly the His Bundle in the intraventricular septal wall. An endocardial screw-in lead having a distal end coupled to a retractable fixation helix wherein a distal portion of the fixation helix extends beyond the lead distal end when the fixation helix is fully retracted or partially extended is positioned in proximity to the His Bundle in the septal wall. The lead body is rotated to attach the distal portion of the fixation helix into the septal wall. The fixation helix is rotated with respect to the lead body to fully extend the fixation helix so that a portion of the fixation helix is in proximity to the His Bundle, enabling provision of electrical stimulation to the His Bundle and/or to sense electrical signals of the heart traversing the His Bundle through the fixation helix.

Abstract translation: 方法和心内膜旋入导致使得能够向心脏提供电刺激，特别是心室间隔壁中的His束。 具有联接到可缩回固定螺旋的远端的心内膜旋入式引线，其中当固定螺旋完全缩回或部分延伸时，固定螺旋的远端部分延伸超出远端，位于接近His束的 隔壁。 旋转导线主体以将固定螺旋的远端部分附接到隔壁。 固定螺旋相对于导线主体旋转以完全延伸固定螺旋，使得固定螺旋的一部分接近His束，使得能够向His束提供电刺激和/或感测电信号的 心脏穿过固定螺旋穿过祂的束。

公开(公告)号：WO03030988B1

公开(公告)日：2003-08-07

申请号：PCT/US0233662

申请日：2002-10-07

Applicant: MEDTRONIC INC

Inventor： ALINDER JASON ,  CASAVANT DAVID A ,  HESS DOUGLAS N ,  GRENZ DAVID A ,  FREIBORG MIKE ,  CLEMENS WILLIAM J ,  RUFF MICHAEL A

IPC: A61N1/05

CPC classification number: A61N1/0573

Abstract: Methods and endocardial screw-in leads for enabling provision of electrical stimulation to the heart, particularly the His Bundle in the intraventricular septal wall. An endocardial screw-in lead having a distal end coupled to a retractable fixation helix wherein a distal portion of the fixation helix extends beyond the lead distal end when the fixation helix is fully retracted or partially extended is positioned in proximity to the His Bundle in the septal wall. The lead body is rotated to attach the distal portion of the fixation helix into the septal wall. The fixation helix is rotated with respect to the lead body to fully extend the fixation helix so that a portion of the fixation helix is in proximity to the His Bundle, enabling provision of electrical stimulation to the His Bundle and/or to sense electrical signals of the heart traversing the His Bundle through the fixation helix.

Abstract translation: 方法和心内螺旋引线，用于对心脏，特别是心室间隔壁中的His束提供电刺激。 一种心内膜螺钉，其具有联接到可缩回的固定螺旋的远端，其中当所述固定螺旋完全缩回或部分延伸时，所述固定螺旋的远端部分延伸超过所述引导远端，所述远端部位于所述固定螺旋 隔壁。 引导体旋转以将固定螺旋的远端部分附接到隔壁中。 固定螺旋线相对于引线体旋转以完全延伸固定螺旋，使得固定螺旋的一部分靠近His束，使得能够向His束提供电刺激和/或感测电信号 心脏通过固定螺旋穿过他的束。

公开(公告)号：WO02058465A2

公开(公告)日：2002-08-01

申请号：PCT/US0149226

申请日：2001-12-19

Applicant: MEDTRONIC INC

Inventor： CLEMENS WILLIAM J ,  HESS DOUGLAS N ,  SOMMERS JOHN L ,  SOYKAN ORHAN

IPC: A61N1/05 ,  A01N

CPC classification number: A61N1/056 ,  A61N2001/0585

Abstract: A medical electrical lead (10) including an inflatable member (12) at a distal tip section, and a system of use, are disclosed. The inflation member is adapted to engage the walls of a cardiac vein or coronary artery to occlude the vessel. According to one aspect of the invention, the inflation member is formed of a bio-absorbable material. In another embodiment, the inflation member is a micro-porous material. The lead of the current invention may include a port located distal to the inflation member is in the inflated state. This allows a fluoroscopic image of a patient's vascular system to be obtained while the lead is in place within a vessel. A perfusion lumen may be provided to allow a partial flow of blood to continue around the inflation member (18) when the inflation member is occluding a vessel. In one embodiment, lead is provided with a lumen for receiving a stiffening menber such as a stylet (64) to aid in lead is placement. According to one method of using the current invention, inflation member may be inflated after the lead is placed at a desired implant site to provide a temporary fixation mechanism during withdrawal of the stiffening member and/or a guide catheter or sheath used to place the lead at the implant site. This temporary fixation mechanism may also be employed to retain a desired lead location while thresholds are obtains. The inflation member may be retained in an inflated state for a longer predetermined period of time until tissue in-growth begins to occur around the lead.

Abstract translation: 公开了一种包括在远侧末端部分处的可膨胀构件（12）和使用系统的医疗电气引线（10）。 充气构件适于接合心脏静脉或冠状动脉的壁以闭塞血管。 根据本发明的一个方面，充气构件由生物可吸收材料形成。 在另一个实施例中，充气构件是微孔材料。 本发明的引线可以包括位于充气构件远侧的端口处于充气状态。 这允许在铅在血管内就位时获得患者血管系统的透视图像。 当充气构件封闭容器时，可以提供灌注腔以允许血液部分流动在充气构件（18）周围继续。 在一个实施例中，引线设置有用于接收诸如探针（64）的加强型的管腔，以帮助引线放置。 根据使用本发明的一种方法，在引线放置在期望的植入位置之后，充气构件可以被充气，以在撤回加强构件和/或用于放置引线的引导导管或护套时提供临时固定机构 在植入部位。 也可以采用该临时固定机构来保持期望的引导位置，同时获得阈值。 膨胀构件可以保持在膨胀状态较长的预定时间段，直到在铅周围开始发生组织增长。