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    21.
    发明专利
    未知

    公开(公告)号：AT355866T

    公开(公告)日：2007-03-15

    申请号：AT01994102

    申请日：2001-11-27

    Applicant: MEDTRONIC INC

    Inventor： OLSEN JAMES M

    IPC: A61K9/22 ,  A61M5/142

    Abstract: A medical device known as an implantable therapeutic substance delivery device is configured for implanting in humans to deliver a therapeutic substance such as pharmaceutical compositions, genetic materials, and biologics to treat a variety of medical conditions such as pain, spastisity, cancer, and many other conditions. The therapeutic substance delivery device has a permanent magnet solenoid pump that is energy efficient, accurate, small, compatible with therapeutic substances, and has many other improvements. The implantable therapeutic substance delivery device has a housing, a therapeutic substance reservoir, a power source, electronics, and a permanent magnet solenoid pump. The therapeutic substance reservoir is configured to contain a therapeutic substance and is coupled to the housing. The power source is carried in the housing to power the electronics and solenoid pump. The electronics are coupled to the solenoid pump and the solenoid pump is coupled to the therapeutic substance reservoir. The permanent magnet solenoid pump is configured for pumping therapeutic substance from the therapeutic substance reservoir through an infusion outlet at a programmed infusion rate. Many embodiments of the permanent magnet solenoid pump and its methods of operation are possible.

    23.
    发明专利
    未知

    公开(公告)号：DE10020495B4

    公开(公告)日：2006-11-16

    申请号：DE10020495

    申请日：2000-04-26

    Applicant: MEDTRONIC INC

    Inventor： ROGERS CHARLES ,  STARKEBAUM WARREN ,  OLSEN JAMES M

    IPC: A61M5/172 ,  A61M1/00 ,  A61M5/14 ,  A61M5/142 ,  A61M5/168 ,  A61M37/00 ,  G05D7/01

    Abstract: An implantable drug delivery device is provided with a passive flow control device is provided in the form of a valve which may assume two flow states. Flow control is achieved by duty cycling the valve using a control module which generates appropriate signals in response to an input telemetry signal corresponding to a desired flow rate. In another embodiment, a passively controlled bolus delivery device is provided to deliver a bolus of drug in addition to normal dosage.

    24.
    发明专利
    未知

    公开(公告)号：DE10117243A1

    公开(公告)日：2001-11-22

    申请号：DE10117243

    申请日：2001-04-06

    Applicant: MEDTRONIC INC

    Inventor： OLSEN JAMES M ,  CHRISTENSON STEVEN ,  HEGLAND MICHAEL

    IPC: A61M5/142 ,  A61M5/14

    Abstract: The present invention relates to an implantable medical device that is used to deliver drugs or other therapeutic agents into a patient. More specifically, the present invention is for a drug infusion device which features a bulkhead having integrated subsystems. The bulkhead is the main structural component of the implantable medical device. The integrated bulkhead of the present invention has all or portions of subassemblies, such as a pump, motor and gear train, electronics, drug fill port, catheter access port, fluid pathways, filter and overpressure mechanism, built into the bulkhead. Integrating the subsystems of the bulkhead simplifies the assembly process and reduces the overall cost of manufacture by reducing the number of components to assemble and reducing the number of manufacturing steps. Additionally, integrating the subassemblies into the bulkhead allows for increased accuracy in controlling the connections between the subsystems, which allows for improved delivery of drugs to the patient. The invention also provides a new configuration of the motor and gear train and pump sub-assemblies within the bulkhead, which provides for an implantable drug infusion pump having a low profile.

    27.
    发明专利
    未知

    公开(公告)号：DE602005005320D1

    公开(公告)日：2008-04-24

    申请号：DE602005005320

    申请日：2005-04-22

    Applicant: MEDTRONIC INC

    Inventor： OLSEN JAMES M ,  MORRIS MARY M ,  HEGLAND MICHAEL ,  BLANCO JUSTIN A

    IPC: F16K1/40 ,  A61M1/00 ,  A61M5/142 ,  A61M5/168 ,  A61M25/00 ,  A61M27/00 ,  A61M31/00 ,  A61M39/10 ,  A61M39/22 ,  F16K47/12 ,  G01F1/68

    Abstract: Catheter systems including one or more flow restrictors are disclosed. The catheter systems may include two or more delivery branches. The delivery branches may be connected to a supply catheter section using a branching catheter connector that may include one or more flow restrictors. The flow restrictors may include a restrictor body located within a lumen with a channel located between the restrictor body and interior surface of the lumen, the channel restricting flow through the lumen past the flow restrictor. The channel may be defined by a groove formed in the restrictor body and/or the interior surface of the lumen. Methods of providing pressure relief by flowing fluid past a flow restrictor are also disclosed.

    29.
    发明专利
    未知

    公开(公告)号：ITRM20010229A1

    公开(公告)日：2002-10-24

    申请号：ITRM20010229

    申请日：2001-04-24

    Applicant: MEDTRONIC INC

    Inventor： CHRISTENSON STEVEN R ,  OLSEN JAMES M ,  HEGLAND MICHAEL

    IPC: A61M5/142

    Abstract: The present invention relates to an implantable medical device that is used to deliver drugs or other therapeutic agents into a patient. More specifically, the present invention is for a drug infusion device which features a bulkhead having integrated subsystems. The bulkhead is the main structural component of the implantable medical device. The integrated bulkhead of the present invention has all or portions of subassemblies, such as a pump, motor and gear train, electronics, drug fill port, catheter access port, fluid pathways, filter and overpressure mechanism, built into the bulkhead. Integrating the subsystems of the bulkhead simplifies the assembly process and reduces the overall cost of manufacture by reducing the number of components to assemble and reducing the number of manufacturing steps. Additionally, integrating the subassemblies into the bulkhead allows for increased accuracy in controlling the connections between the subsystems, which allows for improved delivery of drugs to the patient. The invention also provides a new configuration of the motor and gear train and pump sub-assemblies within the bulkhead, which provides for an implantable drug infusion pump having a low profile.

    30.
    发明专利
    未知

    公开(公告)号：FR2795967A1

    公开(公告)日：2001-01-12

    申请号：FR0005248

    申请日：2000-04-25

    Applicant: MEDTRONIC INC

    Inventor： OLSEN JAMES M

    IPC: A61M5/142 ,  A61M5/168 ,  A61M31/00

    Abstract: A pressure-sensitive overfill protection system for a refillable drug delivery device includes a collapsible link which, in a preferred embodiment, comprises an aneroid having an internal volume of gas at a reference pressure. The collapsible link, in its expanded state, supports on inlet valve in an open position to permit the ingress of new drug fluid into a bellows reservoir. The external surface of the aneroid is exposed to the bellows pressure. When the bellows pressure exceeds the reference pressure, the aneroid collapses and permits the inlet valve to move to a closed position under a biasing force provided by a spring. Further flow of new drug fluid into the drug delivery device is thereby prevented. Moreover, the closure of the valve provides a large increase in pressure is experienced in the refill device and may therefore be sensed by a clinician. Because the overfill protection system is pressure sensitive, it may be used with different sized bellows without modification.

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