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    4.
    发明专利
    未知

    公开(公告)号：FR2808205B1

    公开(公告)日：2005-02-25

    申请号：FR0105396

    申请日：2001-04-20

    Applicant: MEDTRONIC INC

    Inventor： OLSEN JAMES M ,  CHRISTENSON STEVEN R ,  HEGLAND MICHAEL

    IPC: A61M5/142

    Abstract: The present invention relates to an implantable medical device that is used to deliver drugs or other therapeutic agents into a patient. More specifically, the present invention is for a drug infusion device which features a bulkhead having integrated subsystems. The bulkhead is the main structural component of the implantable medical device. The integrated bulkhead of the present invention has all or portions of subassemblies, such as a pump, motor and gear train, electronics, drug fill port, catheter access port, fluid pathways, filter and overpressure mechanism, built into the bulkhead. Integrating the subsystems of the bulkhead simplifies the assembly process and reduces the overall cost of manufacture by reducing the number of components to assemble and reducing the number of manufacturing steps. Additionally, integrating the subassemblies into the bulkhead allows for increased accuracy in controlling the connections between the subsystems, which allows for improved delivery of drugs to the patient. The invention also provides a new configuration of the motor and gear train and pump sub-assemblies within the bulkhead, which provides for an implantable drug infusion pump having a low profile.

    Implantable therapeutic substance delivery device having a permanent magnet solenoid pump
    6.
    发明专利
    Implantable therapeutic substance delivery device having a permanent magnet solenoid pump 未知

    公开(公告)号：AU2002246531A1

    公开(公告)日：2002-10-28

    申请号：AU2002246531

    申请日：2001-11-27

    Applicant: MEDTRONIC INC

    Inventor： OLSEN JAMES M

    IPC: A61K9/22 ,  A61M5/142

    Abstract: A medical device known as an implantable therapeutic substance delivery device is configured for implanting in humans to deliver a therapeutic substance such as pharmaceutical compositions, genetic materials, and biologics to treat a variety of medical conditions such as pain, spastisity, cancer, and many other conditions. The therapeutic substance delivery device has a permanent magnet solenoid pump that is energy efficient, accurate, small, compatible with therapeutic substances, and has many other improvements. The implantable therapeutic substance delivery device has a housing, a therapeutic substance reservoir, a power source, electronics, and a permanent magnet solenoid pump. The therapeutic substance reservoir is configured to contain a therapeutic substance and is coupled to the housing. The power source is carried in the housing to power the electronics and solenoid pump. The electronics are coupled to the solenoid pump and the solenoid pump is coupled to the therapeutic substance reservoir. The permanent magnet solenoid pump is configured for pumping therapeutic substance from the therapeutic substance reservoir through an infusion outlet at a programmed infusion rate. Many embodiments of the permanent magnet solenoid pump and its methods of operation are possible.

    Medication injecting implant has separating partition and sub-assemblies made in one piece from biocompatible material
    7.
    发明专利
    Medication injecting implant has separating partition and sub-assemblies made in one piece from biocompatible material 未知

    公开(公告)号：FR2808205A1

    公开(公告)日：2001-11-02

    申请号：FR0105396

    申请日：2001-04-20

    Applicant: MEDTRONIC INC

    Inventor： OLSEN JAMES M ,  CHRISTENSON STEVEN R ,  HEGLAND MICHAEL

    IPC: A61M5/142

    Abstract: Implant has a separating partition (10) containing at least two sub-assemblies and incorporating a filling orifice (21) and integral access orifice (40) for a catheter, made in one piece from a biocompatible material. It also has a cavity (32) for a filter, a chamber for a pump assembly, a cavity for a pressure overload safety mechanism and another chamber (13) for an electronic system. Implant has a separating partition (10) containing at least two sub-assemblies and incorporating a filling orifice (21) and integral access orifice (40) for a catheter, made in one piece from a biocompatible material, such as a plastic, stainless steel or titanium. It also has a cavity (32) for a filter, a chamber for a pump assembly, a cavity for a pressure overload safety mechanism, and another chamber (13) for an electronic system.

    8.
    发明专利
    未知

    公开(公告)号：DE10020495A1

    公开(公告)日：2001-03-08

    申请号：DE10020495

    申请日：2000-04-26

    Applicant: MEDTRONIC INC

    Inventor： ROGERS CHARLES ,  STARKEBAUM WARREN ,  OLSEN JAMES M

    IPC: A61M5/14 ,  A61M5/142 ,  A61M5/168 ,  A61M5/172 ,  A61M37/00 ,  A61M1/00 ,  G05D7/01

    Abstract: An implantable drug delivery device is provided with a passive flow control device is provided in the form of a valve which may assume two flow states. Flow control is achieved by duty cycling the valve using a control module which generates appropriate signals in response to an input telemetry signal corresponding to a desired flow rate. In another embodiment, a passively controlled bolus delivery device is provided to deliver a bolus of drug in addition to normal dosage.

    9.
    发明专利
    未知

    公开(公告)号：DE602005003355T2

    公开(公告)日：2008-09-11

    申请号：DE602005003355

    申请日：2005-06-07

    Applicant: MEDTRONIC INC

    Inventor： OLSEN JAMES M

    IPC: A61M5/142 ,  A61M5/145 ,  A61M5/148 ,  A61M5/168

    Abstract: A drug delivery system (10) has a positive pressure drug reservoir (15). A pump (19) is in fluid communication with the reservoir (15) via a first fluid passageway (18). The outlet (19b) of the pump (19) is in fluid communication with a first regulator (21). The regulator (21) includes a housing (24) that has a first subchamber (24a) and a second subchamber (24b). The second subchamber (24b) is divided into a lower chamber (28a) and a middle chamber (28b) by a diaphragm (28). A third fluid passageway (32) is positioned between the lower chamber (28a) and the drug reservoir (15), whereby accidental flow from the reservoir (15) to an outlet (21b) is prevented.

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