公开(公告)号：CA2808412C

公开(公告)日：2021-10-12

申请号：CA2808412

申请日：2011-08-18

Applicant: PRESSURE BIOSCIENCES INC

Inventor： LAZAREV ALEXANDER ,  TING EDMUND Y

IPC: G01N1/28 ,  C12M1/33 ,  C12M1/40

Abstract: Described herein is a sample preparation device including a sample delivery source, an inline means of transferring the sample from the sample source into a deformable channel within a pressure vessel, and out of the channel into downstream analysis components, a deformable channel disposed within the pressure vessel, the deformable channel having an inlet end and an outlet end fluidly connectable to high pressure valves and a means to measure the fluid pressure within the deformable channel, an external source of a controlled pressurized fluid fluidly connectable to the pressure vessel and a controller system that monitors and controls the sample fluid pressure by control of the external pressure vessel fluid.

公开(公告)号：AU2016318955A1

公开(公告)日：2018-04-26

申请号：AU2016318955

申请日：2016-09-08

Applicant: PRESSURE BIOSCIENCES INC

Inventor： TING EDMUND Y ,  LAZAREV ALEXANDER ,  MA JUN

IPC: F16K3/24 ,  F16K1/12 ,  F16K1/38 ,  F16K31/62

Abstract: A high pressure valve includes a lever and a variable force generator for facilitating control of opening and closing the valve at high pressures. The high pressure valve includes a housing having a chamber providing fluid communication between a first port and a second port, a pin movable within the chamber between an open position and a closed position. A first end of a lever is coupled to the pin and a second end of the lever is coupled to a variable force generator. The lever pivots about a pivot point. A controller coupled to the variable force generator is configured to adjust a force applied to the second end of the lever by the variable force generator to control the movement of the pin between the open position and the closed position.

公开(公告)号：CA2808412A1

公开(公告)日：2012-02-23

申请号：CA2808412

申请日：2011-08-18

Applicant: PRESSURE BIOSCIENCES INC

Inventor： LAZAREV ALEXANDER ,  TING EDMUND Y

IPC: G01N1/28 ,  C12M1/33 ,  C12M1/40

Abstract: Described herein is a sample preparation device including a sample delivery source, an inline means of transferring the sample from the sample source into a deformable channel within a pressure vessel, and out of the channel into downstream analysis components, a deformable channel disposed within the pressure vessel, the deformable channel having an inlet end and an outlet end fluidly connectable to high pressure valves and a means to measure the fluid pressure within the deformable channel, an external source of a controlled pressurized fluid fluidly connectable to the pressure vessel and a controller system that monitors and controls the sample fluid pressure by control of the external pressure vessel fluid.

公开(公告)号：CA2727246A1

公开(公告)日：2009-11-12

申请号：CA2727246

申请日：2009-05-07

Applicant: PRESSURE BIOSCIENCES INC

Inventor： TAO FENG ,  SCHUMACHER RICHARD ,  LAWRENCE NATHAN ,  GROSS VERA ,  SMEJKAL GARY ,  LAZAREV ALEXANDER ,  HAN RUI

IPC: C12N1/06 ,  B01D57/00 ,  C07K1/14 ,  C12M1/33 ,  C12N1/00 ,  C12N5/00 ,  C12N15/10 ,  C12Q1/68 ,  G01N1/28 ,  G01N1/34

Abstract: Extraction methods that allow a molecular complex (e.g., an organelle) to be extracted from a sample by employing pressure cycling are described.

公开(公告)号：AU2008259821A1

公开(公告)日：2008-12-11

申请号：AU2008259821

申请日：2008-06-02

Applicant: PRESSURE BIOSCIENCES INC

Inventor： LAZAREV ALEXANDER ,  GROSS VERA

IPC: B01D21/01

Abstract: Methods of extracting a component of interest from a plurality of components are described.