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21.发明专利
公开(公告)号：MD3313817T2
公开(公告)日：2021-01-31
申请号：MDE20180438
申请日：2016-06-22
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： BALINT BALAZS , CSEKEI MARTON , SZABO ZOLTAN , SZLAVIK ZOLTAN , KOTSCHY ANDRAS , CHANRION MAIA , GENESTE OLIVIER , CHEN I-JEN , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , SIPOS SZABOLCS , ONDI LEVENTE , PROSZENYAK AGNES
IPC: C07D209/12 , A61K31/381 , A61K31/4355 , A61K31/437 , A61P35/00 , C07D307/80 , C07D307/81 , C07D333/56 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/12 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04
Abstract: Compuşi cu formula (I): unde R1, R2, R3, R4, R5, R6, R7, R8, R14, W, A şi n sunt definiţi în descriere. Medicamente.
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公开(公告)号：HK1254656A1
公开(公告)日：2019-07-26
申请号：HK18113624
申请日：2018-10-24
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： BÁLINT BALÁZS , CSÉKEI MÁRTON , SZABÓ ZOLTÁN , SZLÁVIK ZOLTÁN , KOTSCHY ANDRÁS , CHANRION MAÏA , GENESTE OLIVIER , CHEN I-JEN , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , SIPOS SZABOLCS , ONDI LEVENTE , PROSZENYÁK ÁGNES
IPC: C07D20060101 , A61K20060101 , A61P20060101
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23.发明专利
公开(公告)号：TN2017000524A1
公开(公告)日：2019-04-12
申请号：TN2017000524
申请日：2016-06-22
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： BÁLINT BALÁZS , CHANRION MAÏA , CHEN I-JEN , CSÉKEI MÁRTON , DAVIDSON JAMES EDWARD PAUL , GENESTE OLIVIER , KOTSCHY ANDRÁS , MURRAY JAMES BROOKE , ONDI LEVENTE , PROSZENYÁK ÁGNES , SIPOS SZABOLCS , SZABÓ ZOLTÁN , SZLÁVIK ZOLTÁN
IPC: C07D209/12
Abstract: Compounds of formula (I): wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 14 , W, A and n are as defined in the description. Medicaments.
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24.发明专利
公开(公告)号：MD3313850T2
公开(公告)日：2019-02-28
申请号：MDE20180440
申请日：2016-06-22
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： SZLAVIK ZOLTAN , SZABO ZOLTAN , CSEKEI MARTON , PACZAL ATTILA , KOTSCHY ANDRAS , BRUNO ALAIN , GENESTE OLIVIER , CHEN I-JEN , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , ONDI LEVENTE , RADICS GABOR , SIPOS SZABOLCS , PROSZENYAK AGNES , PERRON-SIERRA FRANCOISE , BALINT BALAZS
IPC: C07D495/04 , A61K31/519 , A61P35/00 , A61P37/00
Abstract: Compuşii cu formula (I): în care R1, R2, R5, R6, R7, R12, X, Y, A, E şi n sunt definiţi în descriere. Medicamente.
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公开(公告)号：HK1250234A1
公开(公告)日：2018-12-07
申请号：HK18109702
申请日：2018-07-26
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： SZLÁVIK ZOLTÁN , SZABÓ ZOLTÁN , CSÉKEI MÁRTON , PACZAL ATTILA , KOTSCHY ANDRÁS , BRUNO ALAIN , GENESTE OLIVIER , CHEN I-JEN , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , ONDI LEVENTE , RADICS GÁBOR , SIPOS SZABOLCS , PROSZENYÁK ÁGNES , PERRON-SIERRA FRANÇOISE , BÁLINT BALÁZS
IPC: C07D20060101 , A61K20060101 , A61P20060101
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Patent Agency Ranking
公开(公告)号：CU20170163A7
公开(公告)日：2018-05-08
申请号：CU20170163
申请日：2016-06-22
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： BÁLINT BALÁZS , CHANRION MAÏA , CHEN I- JEN , CSÉKEI MÁRTON , DAVIDSON JAMES EDWARD PAUL , GENESTE OLIVIER , KOTSCHY ANDRÁS , MURRAY JAMES BROOKE , ONDI LEVENTE , PROSZENYÁK ÁGNES , SIPOS SZABOLCS , SZABÓ ZOLTÁN , SZLÁVIK ZOLTÁN
IPC: A61K31/381 , A61K31/4355 , A61P35/00 , C07D209/12 , C07D307/80 , C07D307/81 , C07D403/12 , C07D405/04 , C07D471/04
Abstract: Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.
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27.发明专利
公开(公告)号：MA42230A
公开(公告)日：2018-05-02
申请号：MA42230
申请日：2016-06-22
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： BÁLINT BALÁZS , CHANRION MAÏA , CHEN I-JEN , CSÉKEI MÁRTON , DAVIDSON JAMES EDWARD PAUL , GENESTE OLIVIER , KOTSCHY ANDRÁS , MURRAY JAMES BROOKE , ONDI LEVENTE , PROSZENYÁK ÁGNES , SIPOS SZABOLCS , SZABÓ ZOLTÁN , SZLÁVIK ZOLTÁN
IPC: A61K31/4355 , A61K31/381 , A61K31/437 , A61P35/00 , C07D209/12 , C07D307/80 , C07D307/81 , C07D333/56 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/12 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04
Abstract: Composés de formule (i) dans laquelle r1, r2, r3, r4, r5, r6, r7, r8, r14, w, a et n sont tels que définis dans la description. L'invention concerne également des médicaments.
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公开(公告)号：CO2017012832A2
公开(公告)日：2018-03-28
申请号：CO2017012832
申请日：2017-12-13
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： SZLÁVIK ZOLTÁN , KOTSCHY ANDRÁS , CHANRION MAÏA , GENESTE OLIVIER , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , BÁLINT BALÁZS , SZABÓ ZOLTÁN , CSÉKEI MÁRTON , CHEN I-JEN , ONDI LEVENTE , PROSZENYÁK ÁGNES , SIPOS SZABOLCS
IPC: C07D209/12 , A61K31/381 , A61K31/4355 , A61K31/437 , A61P35/00 , C07D307/80 , C07D307/81 , C07D333/56 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/12 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04
Abstract: La invención se refiere a nuevos derivados bicíclicos, a un proceso para su preparación y a composiciones farmacéuticas que los contienen. Particularmente, los nuevos derivados bicíclicos tienen la fórmula (I), en la que R1, R2, R3, R4, R5, R6, R7, R8, R14, W, A y n son como se han definido en la descripción. Los compuestos de la presente invención tienen propiedades pro-apoptóticas lo que hace posible usarlos en patologías que implican un defecto en la apoptosis, tal como, por ejemplo, en el tratamiento del cáncer y de enfermedades inmunes y auto-inmunes.
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公开(公告)号：FR3037956B1
公开(公告)日：2017-08-04
申请号：FR1555747
申请日：2015-06-23
Applicant: SERVIER LAB , VERNALIS (R&D) LTD
Inventor： SZLAVIK ZOLTAN , SZABO ZOLTAN , CSEKEI MARTON , PACZAL ATTILA , KOTSCHY ANDRAS , BRUNO ALAIN , GENESTE OLIVIER , CHEN I-JEN , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , ONDI LEVENTE , RADICS GABOR , SIPOS SZABOLCS , PROSZENYAK AGNES , PERRON SIERRA FRANCOISE , BALINT BALAZS
IPC: C07D487/04 , A61K31/519 , A61P35/00 , A61P37/00 , C07D239/04 , C07D333/04
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公开(公告)号：FR3037959A1
公开(公告)日：2016-12-30
申请号：FR1555750
申请日：2015-06-23
Applicant: SERVIER LAB , VERNALIS (R&D) LTD
Inventor： BALINT BALAZS , CSEKEI MARTON , SZABO ZOLTAN , SZLAVIK ZOLTAN , KOTSCHY ANDRAS , CHANRION MAIA , GENESTE OLIVIER , CHEN I-JEN , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , SIPOS SZABOLCS , ONDI LEVENTE , PROSZENYAK AGNES
IPC: C07D487/06 , A61K31/4436 , A61K31/519 , A61P35/00 , A61P37/00 , C07D207/30 , C07D213/02 , C07D239/24 , C07D307/34 , C07D333/04 , C07D471/06
Abstract: Composés de formule (I) : où R1, R2, R3, R4, R5, R6, R7, R8, R14, W, A et n sont tels que définis dans la description. Médicaments.
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