公开(公告)号：JP2003207443A

公开(公告)日：2003-07-25

申请号：JP2002004752

申请日：2002-01-11

Applicant: SHIMADZU CORP

Inventor： ODA ICHIRO ,  KONISHI IKUO ,  TAKEUCHI SADAO ,  SAKAUCHI HISAFUMI ,  WADA YUKIHISA

IPC: G01N21/17 ,  A61B10/00 ,  G01N21/27

Abstract: PROBLEM TO BE SOLVED: To obtain an optimum signal intensity level even if light reception/ transmission conditions such as a light transmission section, a light reception section, or an area between light transmitted/received light differs in a photometric apparatus having a plurality of light transmission points and a plurality of light reception points. SOLUTION: The photometric apparatus that applies light to a specimen and measures light that is discharged to the outside after light is transmitted or reflected in the inside of the specimen comprises a light transmission/reception means 2 having a plurality of light transmission sections for applying light having one or a plurality of wavelengths to the specimen and a plurality of light reception sections for receiving light that is radiated from the specimen, a plurality of amplifiers 4 for amplifying each of measured signals that are measured by each light reception section, and/or a plurality of attenuation means 8 for attenuating each light intensity that is applied to each light reception section. During measurement, each amplification factor in the amplification means and/or each attenuation rate in the attenuation means are changed. An optimum signal strength level is obtained by changing each amplification factor in the amplification means and each attenuation rate in the attenuation means according to light transmission/reception conditions that change during measurement. COPYRIGHT: (C)2003,JPO

公开(公告)号：JP2001324444A

公开(公告)日：2001-11-22

申请号：JP2000140663

申请日：2000-05-12

Applicant: SHIMADZU CORP

Inventor： ODA ICHIRO ,  TSUNASAWA YOSHIO

IPC: G01N21/17 ,  A61B10/00 ,  G06T1/00 ,  G06T7/00

Abstract: PROBLEM TO BE SOLVED: To display images at any arrangement position, without limiting an arrangement position of light transmission/detection points in a light-measuring apparatus and without being affected by a position relationship between an absorption (or absorption change) part inside of a body to be tested and the light transmission/detection point. SOLUTION: This light-measuring apparatus has a light transmission/detection means 2 for illuminating the body to be tested with a light from a plurality of light transmission points and detecting the light passing the body to be tested at a plurality of light detection points, a light intensity signal-measuring means 3 for measuring the light intensity signals of light signals detected by the light transmission/detection means, a sensitivity distribution-forming means 4 for forming for each set of the light transmission and the light detection points of the plurality of light transmission and light detection points a sensitivity distribution showing for each position in the body to be tested a weight to the light intensity signals, and an image-forming means 5 for operating image signals showing an internal state of the body to be tested with the use of the light intensity signals and the sensitivity distributions. The internal state of the body to be tested is displayed by images using the image signals obtained by the image-forming means 5.

公开(公告)号：JPH11230901A

公开(公告)日：1999-08-27

申请号：JP2724098

申请日：1998-02-09

Applicant: SHIMADZU CORP

Inventor： TSUNASAWA YOSHIO ,  ODA ICHIRO

IPC: G01N33/48 ,  A61B5/145 ,  G01N21/17 ,  G01N21/35 ,  G01N21/359 ,  G01N33/02 ,  A61B5/14

Abstract: PROBLEM TO BE SOLVED: To provide a measuring apparatus, for the reflection of light, by which information on a deep part inside an object to be inspected can be measured by using light in a wavelength region having a small penetration depth and by which a component in an organism such as fat, protein, sugar or the like absorbed in a wavelength region of 1000 to about 2500 nm is detected more precisely. SOLUTION: A measuring apparatus is provided with an irradiation part A in which reflected light from the irradiated part of a sample S is not made incident on a detector, in which only light radiated after it is passed through the inside of the sample S so as to be scattered is used as detecting light, in which a deep part can be measured, in which a component in an organism such as fat, protein, sugar or the like absorbed in a wavelength region of 1000 to about 2500 nm can be detected more precisely and in which the sample S is irradiated with light, a detection part B which detects light from the sample S and a light shielding part C which is installed between the irradiation part A and the detection part B. The light shielding part C shields reflected light which is directly incident on the detection part B from the surface of the sample S, and the detection part B detects only scattered light from the inside of the sample S radiated from the surface of the sample S on a side different from the irradiation part A with reference to the light shielding part C.

公开(公告)号：JPH04226641A

公开(公告)日：1992-08-17

申请号：JP41906990

申请日：1990-12-29

Applicant: SHIMADZU CORP

Inventor： ODA ICHIRO ,  ITOI HIROTO

IPC: A61B6/00 ,  A61B6/03 ,  G01N23/00

Abstract: PURPOSE:To eliminate the influence of the motion of a testee body by detecting the motion of the testee body during the operating time of a tomographic device, and subjecting the motion of an operating means to the correction by the motion of the testee body in real time. CONSTITUTION:The noncorrected positions (d), phi of a ray source P and a sensor D are the positions when the positions of the testee body M can be expressed by (X0, Y0, theta0) and, therefore, these positions are corrected by (X-X0, Y-Y0, theta0). The correction of the angle position phi can be executed simply by subtracting the rotation (theta-theta0) of the testee body M therefrom and the corrected angle position is phi-(theta-theta0). Since the displacement position in the beam direction of the testee body M does not affect the result, the position d' obtd. by subtracting the component of the direction perpendicular to the beam in the angle position phi-(theta-theta0) of the displacement vector (X-X0, Y-Y0) at the center of the testee body M from the value (d) is the position on the guide of the ray source P and the sensor D. The angle position phi of the operating device and the position (d) on the guide of the ray source P and the sensor D are corrected at every sampling of the output of the sensor D in such a manner.

公开(公告)号：JP2009257777A

公开(公告)日：2009-11-05

申请号：JP2008103759

申请日：2008-04-11

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： ODA ICHIRO ,  YAJIMA ATSUSHI ,  HASHIZUME KENTARO ,  TSUNASAWA YOSHIO

IPC: G01N21/64

Abstract: PROBLEM TO BE SOLVED: To provide a fluorescence imaging device for imaging in a condition corresponding to a position of a portion to be measured in a biosample.
SOLUTION: An imaging part 2 includes a two-dimensional detector or an optical system for guiding light of an image of the biosample 4 into the two-dimensional detector. A light source device 6 irradiates excitation light selectively from a plurality of mutually different directions to the biosample 4. An imaging operation of the imaging part 2 or a light irradiation operation of the light source device 6 is controlled by a control part 8. An imaging condition setting part 14 for setting an observation direction in which imaging is performed by an operator or an irradiation direction of the excitation light as an imaging condition is provided. The control part 8 controls the imaging part 2 or the light source device 6 so that imaging is performed in the imaging condition set by the imaging condition setting part 14.
COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：提供一种用于在与生物样品中待测量部分的位置相对应的条件下成像的荧光成像装置。 解决方案：成像部件2包括用于将生物样品4的图像的光引导到二维检测器中的二维检测器或光学系统。 光源装置6从多个相互不同的方向选择性地将激发光照射到生物样品4.成像部2的成像操作或光源装置6的光照射操作由控制部8控制。成像 提供用于设置由操作者进行成像的观察方向的条件设定部14或作为成像条件的激发光的照射方向。 控制部分8控制成像部分2或光源装置6，以便在由成像条件设置部分14设置的成像条件下执行成像。（C）2010，JPO＆INPIT

公开(公告)号：JP2009229290A

公开(公告)日：2009-10-08

申请号：JP2008075997

申请日：2008-03-24

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： YAJIMA ATSUSHI ,  HIZUME KENTARO ,  ODA ICHIRO ,  TSUNASAWA YOSHIO

IPC: G01N21/01 ,  A61B10/00 ,  G01N21/17 ,  G01N21/64 ,  G03B15/00

Abstract: PROBLEM TO BE SOLVED: To provide a biological image acquisition apparatus capable of performing multi-directional and simultaneous observations and measurements in a short time and to provide a sample holding apparatus for implementing the biological image acquisition apparatus. SOLUTION: A sample holding member 2 is supported by a supporting mechanism 12. The supporting mechanism 12 supports a pair of opposed end parts of the sample holding member 2. Gaps 14 are provided between unsupported end parts of the sample holding member 2 and the supporting mechanism 12. The gaps 14 are light-passing regions for passing reflected light from reflecting mirrors M3 and M4 on the back side of the sample holding member 2. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 解决的问题：提供能够在短时间内执行多方向同时观测和测量并提供用于实施生物图像获取装置的样本保持装置的生物图像获取装置。 解决方案：样品保持构件2由支撑机构12支撑。支撑机构12支撑样品保持构件2的一对相对端部。间隙14设置在样品保持构件2的未支撑的端部之间 间隙14是用于使来自反射镜M3和M4的反射光通过样品保持构件2背面的光通过区域。（C）2010，JPO＆INPIT

公开(公告)号：JP2007263865A

公开(公告)日：2007-10-11

申请号：JP2006091620

申请日：2006-03-29

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： KITAMURA KEIJI ,  YOSHIZAWA MASAYUKA ,  ODA ICHIRO

IPC: G01T1/161

Abstract: PROBLEM TO BE SOLVED: To radiograph an RI distribution image of a specimen with full sensitivity.
SOLUTION: In this nuclear medicine diagnosis device, before radiographing the RI distribution image, a first C-shaped arm member 5 on which a first γ-ray detector 1 is mounted by an arm member moving mechanism 7 and a second C-shaped arm member 6 on which a second γ-ray detector 2 is mounted thereby are moved in the direction wherein both arm members 5, 6 are brought close, to thereby bring the first and second both γ-ray detectors 1, 2 close to the specimen M. Each tilt angle of the first and second both γ-ray detectors 1, 2 is changed by a detector angle adjusting mechanism 8, to acquire each γ-ray detection attitude. Hereby, the RI distribution image is radiographed, in a state where the first and second both γ-ray detectors 1, 2 are brought sufficiently close to the specimen M, beforehand. As a result, since the number of γ-rays entering γ-ray incident faces 1A, 2A of the first and second both γ ray detectors 1, 2 is increased during radiographing of the RI distribution image, detection sensitivity of the γ-rays is enhanced, and the RI distribution image of the specimen can be radiographed with full sensitivity.
COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：以全面灵敏度对样本的RI分布图像进行放射照相。 解决方案：在该核医学诊断装置中，在对RI分布图像进行X射线照相之前，通过臂部件移动机构7安装有第一γ射线检测器1的第一C形臂部件5， 在其上安装有第二γ射线检测器2的形状的臂构件6沿其两个臂构件5,6的靠近的方向移动，从而使第一和第二两个γ射线检测器1,2接近 试样M.通过检测器角度调整机构8改变第一和第二两个γ射线检测器1,2的每个倾斜角度，以获得每个γ射线检测姿态。 因此，预先在第一和第二两个γ射线检测器1,2充分接近样本M的状态下对RI分布图像进行射线照相。 结果，由于在RI分布图像的X射线照射期间，进入第一和第二γ射线检测器1,2的γ射线入射面1A，2A的γ射线的数量增加，所以γ射线的检测灵敏度为 增强，并且样品的RI分布图像可以以全灵敏度进行射线照相。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2004317396A

公开(公告)日：2004-11-11

申请号：JP2003113811

申请日：2003-04-18

Applicant: Natl Rehabilitation Center For The Disabled ,  Shimadzu Corp ,  国立身体障害者リハビリテーションセンター総長 ,  株式会社島津製作所

Inventor： MORI KOICHI ,  KONISHI IKUO ,  ODA ICHIRO

IPC: G01N21/17 ,  A61B10/00

Abstract: PROBLEM TO BE SOLVED: To allow measurement by a different distance between transmission/reception terminals, and to densify measuring points to obtain a uniform data distribution, in distribution measurement in a projection plane.
SOLUTION: In a means for measuring a plane distribution projected in a measuring objective area by arranging the plurality of transmission terminals and reception terminals plane-likely to measure signals propagated through a measuring object between the transmission terminal and the reception terminal, transmission/reception are conducted using combination of the transmissions terminal and the reception terminals different in the distance between transmission/reception terminals, and a signal different in a propagation distance is detected from the reception terminal. A measured value of the different distance between transmission/reception terminals is thereby acquired in the projected plane in the measuring objective area. The arrangement of the measuring points within the measuring objective area is densified to obtain a uniform data, by combining the plurality of different distances between transmission/reception terminals.
COPYRIGHT: (C)2005,JPO&NCIPI

公开(公告)号：JP2004097590A

公开(公告)日：2004-04-02

申请号：JP2002265111

申请日：2002-09-11

Applicant: Shimadzu Corp ,  Yukio Takashima ,  株式会社島津製作所 ,  高嶋 幸男

Inventor： KONISHI IKUO ,  ODA ICHIRO ,  TAKASHIMA YUKIO

IPC: G01N21/17 ,  A61B5/0408 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/0492 ,  A61B5/145 ,  A61B5/1455 ,  A61B10/00

Abstract: PROBLEM TO BE SOLVED: To provide a probe for somatometry and a probe holder for the somatometry which realize simultaneous measurement by a probe for different kinds of measurement by an electrode and an optical probe. SOLUTION: In the probe for the somatometry, the electrode and the optical probe are provided in the same measuring probe to perform simultaneous measurement by the electrode and the optical probe. In the probe holder for the somatometry, a fitting hole to/from which the probe for the somatometry can freely be attached and detached is bored at a prescribed position to realize the simultaneous measurement by the electrode and the optical probe. COPYRIGHT: (C)2004,JPO

Abstract translation: 要解决的问题：提供用于躯体测量的探针和用于通过电极和光学探针实现用于不同种类的测量的探针的同时测量的体细胞仪的探针保持器。 解决方案：在用于体积测量的探针中，电极和光学探针设置在同一测量探头中，以通过电极和光学探头同时进行测量。 在用于体积测量的探针支架中，可以在规定位置钻出用于体积测量法的探针可以自由地附接和分离的装配孔，以实现由电极和光学探针的同时测量。 版权所有（C）2004，JPO

公开(公告)号：JP2003175019A

公开(公告)日：2003-06-24

申请号：JP2001375732

申请日：2001-12-10

Applicant: SHIMADZU CORP

Inventor： TAKEUCHI SADAO ,  KONISHI IKUO ,  ODA ICHIRO ,  WADA YUKIHISA

IPC: G01N21/17 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/35 ,  G01N21/359

Abstract: PROBLEM TO BE SOLVED: To obtain measurement data by performing one or a plurality of task measurements in accordance with the reaction of a testee without depending on predetermined measurement procedures in optical bioinstrumentation measurements. SOLUTION: Light obtained from an organism by light irradiation is measured, and the measured data are recorded during the measurements. When each of measurement tasks occurs, the task occurrence time of this measurement task is recorded in relation with a task class. The recorded measured data are extracted by using the task class or task occurrence time as an extraction index. When extracting the measured data of a prescribed task class, for example, the task occurrence time is found with the task class as an extraction index and further, the measured data corresponding to this task occurrence time are extracted with this time as an extraction index. Thus, the measurements can be performed without predetermining the measurement procedures of the task measurements and the measured data of the prescribed task class can be extracted. COPYRIGHT: (C)2003,JPO