公开(公告)号：JP2001324444A

公开(公告)日：2001-11-22

申请号：JP2000140663

申请日：2000-05-12

Applicant: SHIMADZU CORP

Inventor： ODA ICHIRO ,  TSUNASAWA YOSHIO

IPC: G01N21/17 ,  A61B10/00 ,  G06T1/00 ,  G06T7/00

Abstract: PROBLEM TO BE SOLVED: To display images at any arrangement position, without limiting an arrangement position of light transmission/detection points in a light-measuring apparatus and without being affected by a position relationship between an absorption (or absorption change) part inside of a body to be tested and the light transmission/detection point. SOLUTION: This light-measuring apparatus has a light transmission/detection means 2 for illuminating the body to be tested with a light from a plurality of light transmission points and detecting the light passing the body to be tested at a plurality of light detection points, a light intensity signal-measuring means 3 for measuring the light intensity signals of light signals detected by the light transmission/detection means, a sensitivity distribution-forming means 4 for forming for each set of the light transmission and the light detection points of the plurality of light transmission and light detection points a sensitivity distribution showing for each position in the body to be tested a weight to the light intensity signals, and an image-forming means 5 for operating image signals showing an internal state of the body to be tested with the use of the light intensity signals and the sensitivity distributions. The internal state of the body to be tested is displayed by images using the image signals obtained by the image-forming means 5.

公开(公告)号：JP2001204685A

公开(公告)日：2001-07-31

申请号：JP2000021440

申请日：2000-01-31

Applicant: SHIMADZU CORP

Inventor： TAMAI TETSUO ,  TSUNASAWA YOSHIO ,  KONISHI IKUO ,  ITO YASUNOBU ,  KOBAYASHI MANAMI

IPC: A61B10/00 ,  A61B1/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1495 ,  G01N33/72

Abstract: PROBLEM TO BE SOLVED: To provide a transvaginal observation device capable of measuring an object without pressing a tissue and obtaining face information with high precision and correctness, and to provide a diagnostic device capable of indicating results by scores with high objectively and without depending on experiences. SOLUTION: The transvaginal observation device is constituted by an optical viewing tube 5 for introducing a light to irradiate and introducing a light emitted from the transvaginal by irradiation, and an optical image measuring means 2 for processing the image of the introduced light to determine a biological information of the transvaginal. The optical image measuring means is provided with an image measuring part for detecting the introduced light with a two-dimensional detector and measuring image data having a plurality of wavelengths with time, and an image computation part for performing image computation using a plurality of image data having different measured wavelengths and measured time. The biological information of the transvaginal is obtained by the image computation. The diagnostic device is provided with, in addition to the transvaginal observation device, an evaluation means for making physiological inflamations in the transvaginal numerical based on the biological information obtained by the image computation and evaluating the figure as a diagnostic criteria for parturition time.

公开(公告)号：JP2001174403A

公开(公告)日：2001-06-29

申请号：JP35859799

申请日：1999-12-17

Applicant: SHIMADZU CORP

Inventor： ITO YASUNOBU ,  KOBAYASHI MANAMI ,  KONISHI IKUO ,  TSUNASAWA YOSHIO ,  TAMAI TETSUO

IPC: A61B5/145 ,  A61B5/1455 ,  G01N21/17 ,  G01N33/72

Abstract: PROBLEM TO BE SOLVED: To enhance the accuracy of a change of a concerned region with time or a change of image-picking up order by correcting the positional shift of an image to be measured due to the movement of a subject. SOLUTION: The apparatus for irradiating a living body with light and detecting the light emitted from the living body with a two-dimensional detector and using the detected image to obtain living body data is equipped with an image measuring means 2 for measuring the two-dimensional measuring image data of the living body including wavelength image data due to a plurality of measuring wavelengths, a correction means 3 for correcting the positional shift of an image between a plurality of measuring image data, a distribution image forming means 5 for calculating the distribution image data related to living body tissue from a plurality of the wavelength image data, an operation means 6 for operating the distribution image data and a display means 7 for displaying the distribution image data and the operation result. The correction means 3 has a function 3a for extracting the position standard on the subject from the measuring image data, a function 3b for calculating the corresponding relation of the position between a plurality of measured images using the position standard and a function 3c for converting the measured images to a standard position using the corresponding relation.

公开(公告)号：JP2001153796A

公开(公告)日：2001-06-08

申请号：JP33396799

申请日：1999-11-25

Applicant: SHIMADZU CORP

Inventor： ITO YASUNOBU ,  KOBAYASHI MANAMI ,  KONISHI IKUO ,  TSUNASAWA YOSHIO ,  TAMAI TETSUO

IPC: A61B5/145 ,  A61B5/1455 ,  A61B5/1495 ,  G01N21/17

Abstract: PROBLEM TO BE SOLVED: To enhance reliability on measured data by compensating for effects by a change in quantity of light detected by a detector in an optical apparatus for measuring a living matter. SOLUTION: In the optical apparatus 1 for measuring the living matter, a light source 2 irradiates a body 10 to be inspected such as the living matter or the like with light, a spectroscopic means 3 spectroscopically measures the light emitted from the living matter, and a two-dimensional detector 4 detects the spectroscopically measured light and obtains spectroscopic pickup images. A control device 5 obtains information on the living matter by processing the spectroscopic pickup images. The optical apparatus 1 is constituted to compensate for effects by a change in quantity of light, with including a detecting means 6 for detecting a quantity of light emitted from the body 10 to be inspected and a compensating means 7 for compensating for the change in quantity of light based on a detected quantity of light.

公开(公告)号：JP2001033381A

公开(公告)日：2001-02-09

申请号：JP21086799

申请日：1999-07-26

Applicant: SHIMADZU CORP

Inventor： KOBAYASHI MANAMI ,  TSUNASAWA YOSHIO ,  ITO YASUNOBU ,  KONISHI IKUO

IPC: A61B5/145 ,  A61B5/1455 ,  G01N21/17 ,  G06T1/00

Abstract: PROBLEM TO BE SOLVED: To simply obtain an absolute value when measured from two-dimensional image information of a specimen obtained by a single two-dimensional detector by multiplying both measured and reference image data by a given weight different at a pixel unit at each measuring wavelength and adding the resultant data. SOLUTION: Radiant rays from a specimen 10unk and a reference material 10std having a constant reflectivity from a light source 11 are detected by a two-dimensional detector 21. Then, measured image data D1(unk) to Dn(unk) having wavelengths λ1 to λn are obtained from the sample 10unk, and reference image data D1(std) to Dn(std) are similarly obtained from the material 10std. A given weight is multiplied by both the image data at each different measured wavelength, and the multiplied data are added at each pixel unit. E.g. a calculation (f) multiplies a given weight by different wavelengths of a difference of both the image data D1 to Dm having wavelengths λ1 to λm from both the image data having the wavelengths λ1 to λn, and adds the multiplied data. Two-dimensional information of an absolute value regarding an organism tissue based on it is obtained. Thus, even if the measured image data is changed due to a change in measuring conditions, the reference data of the same change compensates the change in the conditions.

公开(公告)号：JPH11295218A

公开(公告)日：1999-10-29

申请号：JP9473598

申请日：1998-04-07

Applicant: SHIMADZU CORP

Inventor： TAKEUCHI SADAO ,  TSUNASAWA YOSHIO

IPC: G01N21/27 ,  A61B5/145 ,  A61B5/1495 ,  G01N21/17 ,  A61B5/14

Abstract: PROBLEM TO BE SOLVED: To obtain information from a different depth by one measurement device. SOLUTION: A device is provided with a measurement probe 1 that includes a light emission part 2 for applying light to a specimen and a light reception part 3 including at least two photodetectors 31a and 31b, and a signal processing part 5 that allows a detection signal detected by the light reception part 3 to be subjected to signal processing. The light reception part 3 makes constant the distance between the photodetectors 31a and 31b, and at the same time makes variable the distance to the light emission part 2. The signal processing part 5 uses the distance between the light reception part 3 and the light emission part 2 as a parameter for performing signal processing. For the light reception part 3, the distance between the photodetectors is fixed at fixed distance intervals, and the distance to the light emission part 2 is allowed to be variable in one piece, thus simplifying the configuration of the measurement probe 1, at the same time, performing signal processing for obtaining the optical characteristics of the specimen by one parameter, and simplifying the signal processing.

公开(公告)号：JPH11230901A

公开(公告)日：1999-08-27

申请号：JP2724098

申请日：1998-02-09

Applicant: SHIMADZU CORP

Inventor： TSUNASAWA YOSHIO ,  ODA ICHIRO

IPC: G01N33/48 ,  A61B5/145 ,  G01N21/17 ,  G01N21/35 ,  G01N21/359 ,  G01N33/02 ,  A61B5/14

Abstract: PROBLEM TO BE SOLVED: To provide a measuring apparatus, for the reflection of light, by which information on a deep part inside an object to be inspected can be measured by using light in a wavelength region having a small penetration depth and by which a component in an organism such as fat, protein, sugar or the like absorbed in a wavelength region of 1000 to about 2500 nm is detected more precisely. SOLUTION: A measuring apparatus is provided with an irradiation part A in which reflected light from the irradiated part of a sample S is not made incident on a detector, in which only light radiated after it is passed through the inside of the sample S so as to be scattered is used as detecting light, in which a deep part can be measured, in which a component in an organism such as fat, protein, sugar or the like absorbed in a wavelength region of 1000 to about 2500 nm can be detected more precisely and in which the sample S is irradiated with light, a detection part B which detects light from the sample S and a light shielding part C which is installed between the irradiation part A and the detection part B. The light shielding part C shields reflected light which is directly incident on the detection part B from the surface of the sample S, and the detection part B detects only scattered light from the inside of the sample S radiated from the surface of the sample S on a side different from the irradiation part A with reference to the light shielding part C.

公开(公告)号：JPH08184593A

公开(公告)日：1996-07-16

申请号：JP33920194

申请日：1994-12-29

Applicant: SHIMADZU CORP

Inventor： TSUNASAWA YOSHIO ,  EDA HIDEO ,  IWAMOTO SHINICHI ,  KATSUTA NOBUYUKI ,  YAMAGUCHI TAKESHI ,  TSUNEISHI SHOICHI ,  TAMURA TOMOMI

IPC: G01N33/483 ,  A61B5/145 ,  A61B5/1455 ,  A61B10/00

Abstract: PURPOSE: To obtain an optical probe device whose optical intensity is large and which is disposable. CONSTITUTION: A prism 12 as a light-sending part and a photodiode 13 which is in a position at distance of 3cm from it are installed at a probe 11 so as to be capable of coming into contact with a living body 6. In order to guide light with a plurality of wavelengths to the prism 12, one end of a plastic fibercord 16 as a transmission line is coupled to the prism 12, and the cross-sectional area of the optical fiber 16 is larger than the cross-sectional area of an optical fiber bundle 20 which has bundled quartz fiber cords 20-1 to 20-4. An optical connector part 18 in which both edges are opposed to each other and brought into contact with each other so that the edge of the optical fiber bundle 20 is positioned inside the edge of the optical fiber 16 and which is connected so as to be attachable/detachable is installed at the other end of the optical fiber 16. A signal cable 17 which guides a detection signal to a somatometry apparatus body 40 is connected to the detector 13, and a signal connector part 19 which is connected to the somatometry apparatus body 40 so as to be attachable/detachable is installed at the tip of the signal cable 17.

公开(公告)号：JPH08150135A

公开(公告)日：1996-06-11

申请号：JP32370594

申请日：1994-11-30

Applicant: SHIMADZU CORP

Inventor： WADA YUKIHISA ,  TSUNASAWA YOSHIO ,  IWAMOTO SHINICHI

IPC: G01N1/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B10/00 ,  G01N21/17 ,  A61B5/14

Abstract: PURPOSE: To enable light absorption coefficient and scattering coefficient to be adjusted independently, and also, to enable both to be set accurately, changing the scattering coefficient and the absorption efficient freely, by circulating light absorbing liquid within many tubes, and light scattering liquid outside the tubes, respectively, and passing them measuring sections. CONSTITUTION: A light absorbing liquid supply part 6, a gas exchange part 8 for adjusting the saturation of the oxygen of the light absorber, and a measuring section 10, where the measurement is made by an organism measuring device, are arranged in order along the passage 4 equipped with liquid feed pumps 2a and 2b. And, by adjusting the flow of the pumps 2a and 2b in the light absorbing liquid supply part 6, the concentration of the light absorber of the light absorbing liquid supplied to the passage 4 is adjusted. Moreover, the gas exchange part 8 consists of a gas exchange vessel 30 and a bundle of thin porous pipes 32 which pass therein and allow liquid to pass but do not allow gas to pass through themselves, and light absorbing liquid is circulating in the fine pipe 32, and it is adjusted to light absorbing liquid in desired oxygen saturation by contacting with the gas being adjusted to specified oxygen partial pressure within the gas exchange vessel 30.

公开(公告)号：JPH03230000A

公开(公告)日：1991-10-11

申请号：JP2340890

申请日：1990-01-31

Applicant: SHIMADZU CORP

Inventor： KUSHIDA YUKIFUMI ,  OKUNO YASUHIRO ,  KOBAYASHI MASAO ,  TANIMIZU HIROHARU ,  TSUNASAWA YOSHIO

IPC: G01N1/00 ,  B01L99/00 ,  F04F1/06 ,  F04F3/00

Abstract: PURPOSE:To enable continuous operation by connecting a primary container which is provided with a suction port and whose pressure is reduced at all times and a secondary container which is provided and opening/closing valve which enables to change over into a lower pressure than the primary container and atmospheric pressure of more in series via a valve. CONSTITUTION:A tube 8 provided with a suction nozzle 10 is connected with a primary pressure-reducing bottle 2 which is vacuum-suctioned and whose pressure is reduced at all times via an opening/closing valve Va to such liquid of a reaction tube 12. The primary pressure-reducing bottle 2 is connected with a secondary pressure-reducting bottle 4 via an opening/closing valve Vd from the bottom of the primary pressure-reducing bottle 2. The secondary pressure-reducing bottle 4 discharges liquid in the reaction tube 12 toward outside via an opening/closing valve Vb. The secondary pressure-reducing bottle 4 is connected with a three-way valve Vc which changes over into vacuum suction and atmospheric pressure or pressurization by means of a tube 5. Usually, the opening/closing valves Va, Vd are opened, the opening/closing valve Vb is closed, and the pressure-reducing bottles 2, 4 are operated in a vacuum to such liquid in the reaction tube 12. When liquid is discharged from the pressure-reducing bottle 4, the opening/closing valve Vd is closed, the valve Vb is opened, and the three-way valve Vc is changed over into pressurization condition. Consequently, liquid is discharged while liquid in the reaction tube 12 is continuously suctioned without interruption.