公开(公告)号：DE10348298A1

公开(公告)日：2005-05-19

申请号：DE10348298

申请日：2003-10-17

Applicant: SOLVAY PHARM GMBH

Inventor： SYKES DAVID ,  MOLONEY BRIAN ,  MARRISON LESTER ,  ZIEGLER DIETER ,  MLINARIC MICHAEL ,  BOECKER CHRISTIANE ,  BRUECKNER REINHARD ,  WESKE MICHAEL ,  WITTE KLAUS ,  FISCHER YVAN

IPC: A61K31/353 ,  C07D311/68 ,  C07D407/12 ,  A61K31/352

Abstract: The invention relates to compounds of general formula (I), wherein the meaning of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.

公开(公告)号：AU2004281195A2

公开(公告)日：2005-04-28

申请号：AU2004281195

申请日：2004-10-14

Applicant: SOLVAY PHARM GMBH

Inventor： MOLONEY BRIAN ,  WESKE MICHAEL ,  SYKES DAVID ,  FISCHER YVAN ,  MLINARIC MICHAEL ,  BOECKER CHRISTIANE ,  BRUECKNER REINHARD ,  WITTE KLAUS ,  MARRISON LESTER ,  ZIEGLER DIETER

IPC: A61K31/353 ,  C07D311/68 ,  C07D407/12

Abstract: The invention relates to compounds of general formula (I), wherein the meaning of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.

公开(公告)号：UA96734C2

公开(公告)日：2011-12-12

申请号：UAA200712393

申请日：2006-04-11

Applicant: SOLVAY PHARM GMBH

Inventor： MOLONEY BRIAN ,  MARRISON LESTER ,  CYGLER DITER ,  MLINARIC MICHAEL ,  BOECKER CHRISTIANE ,  WESKE MICHAEL ,  WITTE KLAUS ,  FISCHER YVAN ,  BRUCKNER RAINHARD

IPC: C07D311/68 ,  A61K31/353 ,  A61K31/4025 ,  A61K31/497 ,  A61K31/5355 ,  A61P9/00 ,  C07D405/12 ,  C07D413/12

Abstract: Взаявкеописанысоединенияобщейформулы I, (I)вкоторой R, R, R, R, R, R, R, R, R, Rи n имеютзначения, указанныев описании, которыеимеютсердечно-сосудистуюактивность, атакжеспособполученияэтихсоединенийи промежуточныепродукты. Крометого, описаныфармацевтическиекомпозиции, которыесодержатсоединенияформулы I.

公开(公告)号：HRP20080602T3

公开(公告)日：2008-12-31

申请号：HRP20080602

申请日：2008-11-20

Applicant: SOLVAY PHARM GMBH

Inventor： SYKES DAVID ,  MOLONEY BRIAN ,  MARRISON LESTER ,  ZIEGLER DIETER ,  MLINARIC MICHAEL ,  BOECKER CHRISTIANE ,  BRUECKNER REINHARD ,  WESKE MICHAEL ,  WITTE KLAUS ,  FISCHER YVAN

IPC: C07D201/00 ,  A61K31/353 ,  C07D311/68 ,  C07D407/12

Abstract: The invention relates to compounds of general formula (I), wherein the meaning of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.

公开(公告)号：PT1678130E

公开(公告)日：2008-10-08

申请号：PT04817204

申请日：2004-10-14

Applicant: SOLVAY PHARM GMBH

Inventor： ZIEGLER DIETER ,  MOLONEY BRIAN ,  SYKES DAVID ,  MARRISON LESTER ,  MLINARIC MICHAEL ,  BOECKER CHRISTIANE ,  BRUECKNER REINHARD ,  WESKE MICHAEL ,  WITTE KLAUS ,  FISCHER YVAN

IPC: C07D201/00 ,  A61K31/353 ,  C07D311/68 ,  C07D407/12

公开(公告)号：DE502004007916D1

公开(公告)日：2008-10-02

申请号：DE502004007916

申请日：2004-10-14

Applicant: SOLVAY PHARM GMBH

Inventor： SYKES DAVID ,  MOLONEY BRIAN ,  MARRISON LESTER ,  ZIEGLER DIETER ,  MLINARIC MICHAEL ,  BOECKER CHRISTIANE ,  BRUECKNER REINHARD ,  WESKE MICHAEL ,  WITTE KLAUS ,  FISCHER YVAN

IPC: C07D201/00 ,  A61K31/353 ,  C07D311/68 ,  C07D407/12

Abstract: The invention relates to compounds of general formula (I), wherein the meaning of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.

公开(公告)号：BRPI0415523A

公开(公告)日：2006-12-26

申请号：BRPI0415523

申请日：2004-10-14

Applicant: SOLVAY PHARM GMBH

Inventor： SYKES DAVID ,  MOLONEY BRIAN ,  MARRISON LESTER ,  ZIEGLER DIETER ,  MLINARIC MICHAEL ,  BOECKER CHRISTIANE ,  BRUECKNER REINHARD ,  WESKE MICHAEL ,  WITTE KLAUS ,  FISCHER YVAN

IPC: A61K31/353 ,  C07D311/68 ,  C07D407/12

Abstract: The invention relates to compounds of general formula (I), wherein the meaning of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.

公开(公告)号：CA2604356A1

公开(公告)日：2006-10-19

申请号：CA2604356

申请日：2006-04-11

Applicant: SOLVAY PHARM GMBH

Inventor： BRUECKNER REINHARD ,  MLINARIC MICHAEL ,  MOLONEY BRIAN ,  BOECKER CHRISTIANE ,  FISCHER YVAN ,  MARRISON LESTER ,  ZIEGLER DIETER ,  WITTE KLAUS ,  WESKE MICHAEL

IPC: C07D311/68 ,  A61K31/353 ,  A61K31/4025 ,  A61K31/453 ,  A61K31/497 ,  A61K31/5355 ,  A61P9/00 ,  C07D405/12 ,  C07D413/12

Abstract: Cardiovascular active compounds of the general formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process are described. Furthermore, pharmaceutical compositions comprising the compounds of Formula (I) are specified.

公开(公告)号：CA2542813A1

公开(公告)日：2005-04-28

申请号：CA2542813

申请日：2004-10-14

Applicant: SOLVAY PHARM GMBH

Inventor： BOECKER CHRISTIANE ,  BRUECKNER REINHARD ,  MLINARIC MICHAEL ,  ZIEGLER DIETER ,  MARRISON LESTER ,  MOLONEY BRIAN ,  WESKE MICHAEL ,  SYKES DAVID ,  WITTE KLAUS ,  FISCHER YVAN

IPC: C07D311/70 ,  A61K31/353 ,  A61P9/00 ,  A61P37/00 ,  C07D311/68 ,  C07D407/12

Abstract: The invention relates to compounds of general formula (I), wherein the meani ng of R1, R2, R3, R4, R5 and R6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.