公开(公告)号：WO1994006922A1

公开(公告)日：1994-03-31

申请号：PCT/US1993009031

申请日：1993-09-23

Applicant: THE UNIVERSITY OF CONNECTICUT

Inventor： THE UNIVERSITY OF CONNECTICUT ,  WU, George, Y. ,  WU, Catherine, H.

IPC: C12N15/87

CPC classification number: C12N15/87 ,  A61K48/00

Abstract: The expression of polynucleotide introduced into a cell by means of a targeted complex of the polynucleotide linked to a cell-specific binding agent can be enhanced and prolonged by inhibiting translocation or fusion of endosomes to lysosomes.

Abstract translation: 通过与细胞特异性结合剂连接的多核苷酸的靶向复合物引入细胞的多核苷酸的表达可以通过抑制内体与溶酶体的易位或融合来增强和延长。

公开(公告)号：WO1993001612A1

公开(公告)日：1993-01-21

申请号：PCT/US1992005765

申请日：1992-07-09

Applicant: THE UNIVERSITY OF CONNECTICUT

Inventor： THE UNIVERSITY OF CONNECTICUT ,  NUDELMAN, Sol ,  OUIMETTE, Donald, R.

IPC: H01J29/39

CPC classification number: H01J31/38 ,  H01J29/39 ,  H04N5/32

Abstract: A large area video camera is suitable for high energy imaging applications. The sensor-target of the camera tube is composed of TlBr or a two layer structure comprising CsI and a phototconductive layer of materials such as amorphous silicon, amorphous selenium, cadmium sulphide, antimony trisulphide or antimony sulphide oxysulphide. A disclosed tube incorporates various modifications for dealing with problems associated with stray capacitance.