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21.发明专利
公开(公告)号：DK2230308T3
公开(公告)日：2013-05-06
申请号：DK09176251
申请日：2001-06-05
Applicant: UCB PHARMA SA
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22.发明专利
公开(公告)号：PT2230308E
公开(公告)日：2013-05-03
申请号：PT09176251
申请日：2001-06-05
Applicant: UCB PHARMA SA
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23.发明专利
公开(公告)号：IS2808B
公开(公告)日：2012-09-15
申请号：IS6217
申请日：2002-01-03
Applicant: UCB PHARMA SA
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24.发明专利
公开(公告)号：HK1148776A1
公开(公告)日：2011-09-16
申请号：HK11102887
申请日：2011-03-22
Applicant: UCB PHARMA SA
Inventor： ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL , KING DAVID JOHN
IPC: C12N20060101 , A61K39/395 , C12N15/09 , A61K47/48 , A61P20060101 , A61P19/02 , A61P29/00 , A61P37/06 , C07K20060101 , C07K16/24 , C07K16/46 , C12N1/21 , C12N15/13 , C12P21/02 , C12P21/08
Abstract: There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNF± There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNF±
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25.发明专利
公开(公告)号：HK1051385A1
公开(公告)日：2003-08-01
申请号：HK03103635
申请日：2003-05-22
Applicant: UCB PHARMA SA
Inventor： ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL , KING DAVID JOHN
IPC: C12N15/09 , A61K39/395 , A61K47/48 , A61P20100101 , A61P19/02 , A61P29/00 , A61P37/06 , C07K20100101 , C07K16/24 , C07K16/46 , C12N20100101 , C12N1/21 , C12N15/13 , C12P21/02 , C12P21/08
Abstract: There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNF± There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNF±
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Patent Agency Ranking
公开(公告)号：NO20160694A1
公开(公告)日：2002-04-08
申请号：NO20160694
申请日：2016-04-26
Applicant: UCB PHARMA SA
Inventor： KING DAVID JOHN , ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL
IPC: C07K16/24 , A61K39/395 , C12N15/09 , A61K47/48 , A61P19/02 , A61P29/00 , A61P37/06 , C07K16/46 , C12N1/21 , C12N15/13 , C12P21/02 , C12P21/08
Abstract: Oppfinnelsen angår et antistoffmolekyl med spesifisitet for human TNFa, og angår også DNA sekvenser som koder for kjedene til antistoffmolekylet, vektorer, transformerte vertceller, fremgangsmåte for fremstilling av antistoffmolekylet, et terapeutisk/diagnostisk preparat samt anvendelser av antistoffmolekylet for behandling av sykdommer mediert ved TNFa.
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27.发明专利
公开(公告)号：NO20131316L
公开(公告)日：2002-04-08
申请号：NO20131316
申请日：2013-10-01
Applicant: UCB PHARMA SA
Inventor： KING DAVID JOHN , ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL
IPC: C07K16/24 , A61K39/395 , C12N15/09 , A61K47/48 , A61P19/02 , A61P29/00 , A61P37/06 , C07K16/46 , C12N1/21 , C12N15/13 , C12P21/02 , C12P21/08
Abstract: Oppfinnelsen angår et antistoffmolekyl med spesifisitet for human TNFa, og angår også DNA sekvenser som koder for kjedene til antistoffmolekylet, vektorer, transformerte vertceller, fremgangsmåte for fremstilling av antistoffmolekylet, et terapeutisk/diagnostisk preparat samt anvendelser av antistoffmolekylet for behandling av sykdommer mediert ved TNFa.
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28.发明专利
公开(公告)号：CY1118220T1
公开(公告)日：2017-06-28
申请号：CY161101159
申请日：2016-11-10
Applicant: UCB PHARMA SA
Inventor： ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL , KING DAVID JOHN
IPC: C12N15/09 , C12N15/13 , A61K39/395 , A61K47/48 , A61P19/02 , A61P29/00 , A61P37/06 , C07K16/24 , C07K16/46 , C07K19/00 , C12N1/21 , C12N15/62 , C12N15/70 , C12P21/02 , C12P21/08
Abstract: Περιγράφονταιμόριααντισωμάτωνπουπεριέχουντουλάχιστονένα CDR προερχόμενοαπόμονοκλωνικάαντισώματαποντικού, μεειδικότηταπροςτονανθρώπινο TNFa. Περιγράφεταιεπίσηςένααντίσωμαμεμοσχευμένα CDR στοοποίοτουλάχιστονέναεκτων CDR είναιέναυβριδικό CDR. Περιγράφονταιεπιπλέοναλληλουχίες DNA πουκωδικοποιούντιςαλυσίδεςτωναντισωμάτων, φορείς, μετασχηματισμένακύτταραξενιστέςκαιχρήσειςτωναντισωμάτωνστηναντιμετώπισηνοσημάτωνπουεξαρτώνταιαπότον TNFa.
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29.发明专利
公开(公告)号：SK288343B6
公开(公告)日：2016-04-01
申请号：SK3152002
申请日：2001-06-05
Applicant: UCB PHARMA SA
Inventor： ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL , KING DAVID JOHN
IPC: A61K39/395 , C07K16/24 , A61K47/48 , C12N15/09 , A61P19/02 , A61P29/00 , A61P37/06 , C07K16/46 , C07K19/00 , C12N1/21 , C12N15/13 , C12N15/62 , C12N15/70 , C12P21/02 , C12P21/08
Abstract: Predložený vynález sa týka protilátkových molekúl, ktoré sú špecifické pre antigénne determinanty nádorového nekrotického faktoru alfa (TNF?) a ktoré obsahujú aspoň jeden úsek CDR z myšej monoklonálnej protilátky. Predložený vynález sa tiež týka tzv. CDR-očkovaných protilátok, kde aspoň jeden z úsekov CDR je hybridný CDR. Ďalej je predmetom DNA sekvencia kódujúca reťazce molekuly protilátky a tiež vektory a transformované hostiteľské bunky. Vynález sa ďalej týka terapeutického využitia protilátkových molekúl na liečenie chorôb sprostredkovaných TNF?.
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公开(公告)号：PL218516B1
公开(公告)日：2014-12-31
申请号：PL39935101
申请日：2001-06-05
Applicant: UCB PHARMA SA
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