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21.
公开(公告)号:DK2230308T3
公开(公告)日:2013-05-06
申请号:DK09176251
申请日:2001-06-05
Applicant: UCB PHARMA SA
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22.
公开(公告)号:PT2230308E
公开(公告)日:2013-05-03
申请号:PT09176251
申请日:2001-06-05
Applicant: UCB PHARMA SA
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23.
公开(公告)号:IS2808B
公开(公告)日:2012-09-15
申请号:IS6217
申请日:2002-01-03
Applicant: UCB PHARMA SA
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24.
公开(公告)号:HK1148776A1
公开(公告)日:2011-09-16
申请号:HK11102887
申请日:2011-03-22
Applicant: UCB PHARMA SA
Inventor: ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL , KING DAVID JOHN
IPC: C12N20060101 , A61K39/395 , C12N15/09 , A61K47/48 , A61P20060101 , A61P19/02 , A61P29/00 , A61P37/06 , C07K20060101 , C07K16/24 , C07K16/46 , C12N1/21 , C12N15/13 , C12P21/02 , C12P21/08
Abstract: There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNF± There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNF±
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25.
公开(公告)号:HK1051385A1
公开(公告)日:2003-08-01
申请号:HK03103635
申请日:2003-05-22
Applicant: UCB PHARMA SA
Inventor: ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL , KING DAVID JOHN
IPC: C12N15/09 , A61K39/395 , A61K47/48 , A61P20100101 , A61P19/02 , A61P29/00 , A61P37/06 , C07K20100101 , C07K16/24 , C07K16/46 , C12N20100101 , C12N1/21 , C12N15/13 , C12P21/02 , C12P21/08
Abstract: There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNF± There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNF±
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公开(公告)号:NO20160694A1
公开(公告)日:2002-04-08
申请号:NO20160694
申请日:2016-04-26
Applicant: UCB PHARMA SA
Inventor: KING DAVID JOHN , ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL
IPC: C07K16/24 , A61K39/395 , C12N15/09 , A61K47/48 , A61P19/02 , A61P29/00 , A61P37/06 , C07K16/46 , C12N1/21 , C12N15/13 , C12P21/02 , C12P21/08
Abstract: Oppfinnelsen angår et antistoffmolekyl med spesifisitet for human TNFa, og angår også DNA sekvenser som koder for kjedene til antistoffmolekylet, vektorer, transformerte vertceller, fremgangsmåte for fremstilling av antistoffmolekylet, et terapeutisk/diagnostisk preparat samt anvendelser av antistoffmolekylet for behandling av sykdommer mediert ved TNFa.
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27.
公开(公告)号:NO20131316L
公开(公告)日:2002-04-08
申请号:NO20131316
申请日:2013-10-01
Applicant: UCB PHARMA SA
Inventor: KING DAVID JOHN , ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL
IPC: C07K16/24 , A61K39/395 , C12N15/09 , A61K47/48 , A61P19/02 , A61P29/00 , A61P37/06 , C07K16/46 , C12N1/21 , C12N15/13 , C12P21/02 , C12P21/08
Abstract: Oppfinnelsen angår et antistoffmolekyl med spesifisitet for human TNFa, og angår også DNA sekvenser som koder for kjedene til antistoffmolekylet, vektorer, transformerte vertceller, fremgangsmåte for fremstilling av antistoffmolekylet, et terapeutisk/diagnostisk preparat samt anvendelser av antistoffmolekylet for behandling av sykdommer mediert ved TNFa.
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28.
公开(公告)号:SK288706B6
公开(公告)日:2019-10-02
申请号:SK500812015
申请日:2001-06-05
Applicant: UCB PHARMA SA
Inventor: ATHWAL DILJEET SINGH , BROWN DEREK THOMAS , WEIR ANDREW NEIL CHARLES , POPPLEWELL ANDREW GEORGE , CHAPMAN ANDREW PAUL , KING DAVID JOHN
IPC: C07K16/24 , A61K39/395 , A61K47/68 , A61P19/02 , A61P37/06 , C07K16/46 , C07K19/00 , C12N1/21 , C12N15/13 , C12N15/62 , C12N15/70
Abstract: Vynález sa týka protilátkových molekúl, ktoré sú špecifické pre antigénne determinanty nádorového nekrotického faktora alfa (TNFα). Na C-konci ťažkého reťazca týchto molekúl je pripojená efektorová alebo reportérová molekula, výhodne metoxypoly(etylénglykol). Vynález sa ďalej týka terapeutického použitia protilátkových molekúl na liečenie chorôb sprostredkovaných TNFα.
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29.
公开(公告)号:DK3059314T3
公开(公告)日:2019-02-18
申请号:DK16154916
申请日:2001-06-05
Applicant: UCB PHARMA SA
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公开(公告)号:HU230561B1
公开(公告)日:2016-12-28
申请号:HU0202346
申请日:2001-06-05
Applicant: UCB PHARMA SA
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