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公开(公告)号：DE60237778D1
公开(公告)日：2010-11-04
申请号：DE60237778
申请日：2002-10-10
Applicant: UCB PHARMA SA
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公开(公告)号：AT482234T
公开(公告)日：2010-10-15
申请号：AT02800666
申请日：2002-10-10
Applicant: UCB PHARMA SA
Inventor： POPPLEWELL ANDREW GEORGE , TICKLE SIMON PETER , ZINKEWICH-PEOTTI KAREN , MORRISON ROBERT KENDALL
IPC: C07K16/28 , C12N15/09 , A61K39/395 , A61K47/48 , A61P17/00 , A61P17/06 , A61P19/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P37/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/13 , C12P21/02 , C12P21/08
Abstract: There are disclosed antibody molecules containing at least on CDR derived from a mouse monoclonal antibody having specificity for human KDR. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases in which VEGF and/or KDR are implicated.
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公开(公告)号：ES2341708T3
公开(公告)日：2010-06-25
申请号：ES03718974
申请日：2003-05-02
Applicant: UCB PHARMA SA
IPC: C07K16/18 , C07K16/28 , A61K31/7088 , A61K38/16 , A61K39/395 , A61P35/00 , C12N5/10 , C12N15/13 , C12N15/63 , C12N15/85 , C12P21/00
Abstract: Una molécula de anticuerpo que tiene especificidad para el CD22 humano, que comprende una cadena pesada en la que el dominio variable comprende la SEQ ID NO: 1 para CDR-H1, la secuencia GINPGNNYATYRRKFQG de gH7 de la Figura 6 o la SEQ ID NO: 2 o la SEQ ID NO: 13 o la SEQ ID NO: 15 o la SEQ ID NO: 16 para CDR-H2, y la SEQ ID NO: 3 para CDR-H3, y una cadena ligera en la que el dominio variable comprende la SEQ ID NO: 4 para CDR-L1, la SEQ ID NO: 5 para CDR-L2 y la SEQ ID NO: 6 para CDR-L3.
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公开(公告)号：AT462729T
公开(公告)日：2010-04-15
申请号：AT03718974
申请日：2003-05-02
Applicant: UCB PHARMA SA
IPC: C07K16/18 , C07K16/28 , A61K31/7088 , A61K38/16 , A61K39/395 , A61P35/00 , C12N5/10 , C12N15/13 , C12N15/63 , C12N15/85 , C12P21/00
Abstract: There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human CD22. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a modified CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by cells expressing CD22.
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公开(公告)号：HK1071762A1
公开(公告)日：2005-07-29
申请号：HK05104462
申请日：2005-05-27
Applicant: UCB PHARMA SA
IPC: C07K16/18 , A61K20060101 , A61K38/16 , A61K39/395 , A61P20060101 , A61P35/00 , C07K20060101 , C07K16/28 , C12N20060101 , C12N15/13 , C12N15/63 , C12P21/00
Abstract: There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human CD22. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a modified CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by cells expressing CD22.
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Patent Agency Ranking
公开(公告)号：CA2584222C
公开(公告)日：2016-01-05
申请号：CA2584222
申请日：2005-11-16
Applicant: UCB PHARMA SA
Inventor： ADAMS RALPH , POPPLEWELL ANDREW GEORGE , RAPECKI STEPHEN EDWARD , TICKLE SIMON PETER
IPC: C12N15/13 , A61K39/395 , A61K47/48 , A61P29/00 , A61P37/02 , A61P43/00 , C07K14/54 , C07K16/24 , C12N5/16 , C12N15/63 , C12P21/08
Abstract: The invention relates to an antibody molecule having specificity for antigenic determinants of IL- 17, therapeutic uses of the antibody molecule and methods for producing said antibody molecule.
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公开(公告)号：NO336201B1
公开(公告)日：2015-06-15
申请号：NO20044742
申请日：2004-11-02
Applicant: UCB PHARMA SA
Abstract: SAMMENDRAG Oppfinnelsen vedrører antistoffmolekyler inneholdende minst ett CDR avledet fra et mus monoklonalt antistoff med spesifisitet for humant CD22. Oppfinnelsen vedrører også et CDR-podet antistoff hvor minst ett av CDR'ene er et modifisert CDR. Videre vedrører oppfinnelsen DNA-sekvenser som koder for kjedene til antistoffmolekylene, vektorer, transformerte vertsceller og anvendelser av antistoffmolekylene for behandling av sykdommer mediert ved celler som uttrykker CD22.
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公开(公告)号：RS53215B
公开(公告)日：2014-08-29
申请号：RSP20140125
申请日：2005-11-16
Applicant: UCB PHARMA SA
Inventor： ADAMS RALPH , POPPLEWELL ANDREW GEORGE , RAPECKI STEPHEN EDWARD , TICKLE SIMON PETER
Abstract: The invention relates to an antibody molecule having specificity for antigenic determinants of IL-17, therapeutic uses of the antibody molecule and methods for producing said antibody molecule.
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公开(公告)号：PL1814915T3
公开(公告)日：2014-06-30
申请号：PL05803526
申请日：2005-11-16
Applicant: UCB PHARMA SA
Inventor： ADAMS RALPH , POPPLEWELL ANDREW GEORGE , RAPECKI STEPHEN EDWARD , TICKLE SIMON PETER
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30.发明专利
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