公开(公告)号：EP2876432A1

公开(公告)日：2015-05-27

申请号：EP13819199.4

申请日：2013-07-17

Applicant: Universal Bio Research Co., Ltd.

Inventor： TAJIMA Hideji ,  SUGIMOTO Takaki ,  MATSUKUBO Yu ,  KOBAYASHI Shuuichi ,  UEDA Tetsuya

IPC: G01N21/64 ,  G01N21/78 ,  G01N35/10

Abstract: The invention relates to a light measurement apparatus for a reaction vessel, and a light measurement method, whereby the optical state on the inside of a reaction vessel can be measured efficiently and reliably.
The light measurement apparatus includes: a plurality of linking portions to which is provided front ends of light guide portions that optically connect with the interior of the reaction vessel that is linkable with reaction vessels; a connecting end arranging body that has an arranging surface that arranges and supports along a predetermined path, a plurality of connecting ends to which is provided back ends of the light guide portions, in which the front ends thereof are provided to the linking portions, the connecting ends are provided corresponding to the respective linking portions; a measurement device that has measuring ends that are successively optically connectable with the respective connecting ends, and in which light based on the optical state is receivable by means of optical connections between the connecting ends and the measuring ends; and a light guide switching mechanism that successively optically connects the respective connecting ends and the respective measuring ends.

Abstract translation: 本发明涉及一种用于反应容器的光测量装置和光测量方法，由此能够有效且可靠地测量反应容器内部的光学状态。 光测量装置包括：多个连接部分，其设置在与反应容器可连接的反应容器的内部光学连接的导光部分的前端; 具有沿预定路径布置和支撑的布置表面的连接端布置体，多个连接端设置在其前端设置到连接部分的导光部的后端， 对应于相应的连接部分设置连接端; 测量装置，其具有可以与各个连接端连续光学连接的测量端，并且其中基于光学状态的光可以通过连接端和测量端之间的光学连接而被接收; 以及导光切换机构，其连续地连接各个连接端和相应的测量端。

公开(公告)号：EP2679664A1

公开(公告)日：2014-01-01

申请号：EP11859097.5

申请日：2011-08-19

Applicant: Universal Bio Research Co., Ltd.

Inventor： TAJIMA Hideji

IPC: C12M1/00 ,  C12M1/34 ,  C12M1/38 ,  G01N1/10 ,  G01N35/02

CPC classification number: B65D7/12 ,  B01L3/50855 ,  B01L3/523 ,  B01L3/5635 ,  B01L7/52 ,  B01L2200/028 ,  B01L2300/044 ,  B01L2300/0832 ,  B01L2300/1805 ,  B01L2300/1822 ,  G01N2201/0826

Abstract: The invention relates to a reaction container and a method for producing the reaction container, and provides a low-cost reaction container which is capable of consistently, quickly, and efficiently performing a process that includes a reaction such as extraction or amplification of a nucleic acid, while saving user's trouble without increasing the scale of the device.
The reaction container is configured to comprise: one or two or more housing parts for reactions comprising: a narrow-mouthed piping part in which a reaction reagent or a portion thereof is housed or is housable; a wide-mouthed piping part that is communicated with the narrow-mouthed piping part and provided on an upper side of the narrow-mouthed piping part, and has an aperture that is wider than an aperture of the narrow-mouthed piping part; and a punchable film provided such that it partitions an interval between the wide-mouthed piping part and the narrow-mouthed piping part.

Abstract translation: 本发明涉及反应容器和反应容器的制造方法，提供一种低成本的反应容器，其能够一贯，快速，有效地进行包括反应的过程，例如提取或扩增核酸 同时在不增加设备规模的同时节省用户的麻烦。 反应容器被构造成包括：用于反应的一个或两个或更多个壳体部分，包括：其中容纳有反应试剂或其一部分或可容纳的窄口管道部分; 与狭窄的管道部分连通并设置在狭窄的管道部分的上侧的宽口管部分，并且具有比狭窄的管道部分的孔宽的孔; 以及设置成使得其分开宽口管道部分和窄口管道部分之间的间隔的可冲压膜。

公开(公告)号：EP2672250A1

公开(公告)日：2013-12-11

申请号：EP12742612.0

申请日：2012-02-06

Applicant: Universal Bio Research Co., Ltd.

Inventor： TAJIMA Hideji

IPC: G01N21/13 ,  C12Q1/68 ,  G01N21/15 ,  G01N21/64 ,  G01N35/00 ,  G01N35/02 ,  G01N35/10

Abstract: The invention relates to an automatic response/light measurement device and a method therefor, and the purpose is to effectively and quickly perform an optical measurement relating to a reaction with high reliability without increasing a device size. The device is configured to have: a container group in which a plurality of reaction containers are arranged; a measurement mount provided with a plurality of coupling ends that are joinable with apertures of the reaction containers, and have light guide portions that optically connect with the interior of the joined reaction containers; a mount transfer mechanism; a measuring device provided on the mount and having a measuring end having at least one light guide portion that is optically connectable to the light guide portions of the coupling ends, that is able to receive light based on an optical state within the reaction containers via the measuring end; an on-mount measuring end transfer mechanism that makes the measuring end movable on the mount; and a measurement control portion that, following control of the mount transfer mechanism such that the coupling ends are simultaneously joined with the apertures of the reaction containers, controls the on-mount measuring end transfer mechanism such that the light guide portions of the coupling ends and the light guide portion of the measuring end are successively optically connected, and instructs a measurement by the measuring device.

Abstract translation: 本发明涉及一种自动响应/光测量装置及其方法，其目的是在不增加设备尺寸的情况下有效且快速地执行与高可靠性的反应有关的光学测量。 该装置被配置为具有：多个反应容器布置在其中的容器组; 测量座，其具有可与所述反应容器的孔连接的多个连接端，并且具有与所述连接的反应容器的内部光学连接的导光部; 安装传送机构; 测量装置，其设置在所述安装件上，并且具有测量端，所述测量端具有至少一个导光部分，所述至少一个导光部分可光学地连接到所述耦合端的导光部分，所述光导部分能够基于所述反应容器内的所述光学状态 测量端 安装测量端传送机构，使得测量端能够在安装座上移动; 以及测量控制部分，其中，随着所述安装传送机构的控制使得所述联接端部与所述反应容器的孔同时连接，控制所述安装的测量端传送机构，使得所述联接器的导光部分终止， 测量端的导光部分依次光学连接，并指示测量装置的测量。

公开(公告)号：EP2500101A1

公开(公告)日：2012-09-19

申请号：EP10830035.1

申请日：2010-11-12

Applicant: Universal Bio Research Co., Ltd.

Inventor： TAJIMA Hideji

IPC: B03C1/00 ,  B01J20/28 ,  G01N33/543 ,  G01N33/553

CPC classification number: B03C1/015 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N33/54326

Abstract: The present invention relates to a magnetic reagent, a magnetic reagent kit, a method for treating magnetic carriers, and a treatment device therefor, with an object of quickly and efficiently treating magnetic carriers of a micro particle diameter including nanosized magnetic carriers.
The magnetic reagent or magnetic reagent kit includes: a plurality of magnetic carriers which can be magnetized by being exposed to a magnetic field, can be bonded to a predetermined chemical substance or living organism in a liquid, and that have a particle diameter that enables them to be suspended in the liquid; and a plurality of treatment promoting magnetic particles which can be magnetized by being exposed to a magnetic field and thus can have the magnetic carriers adsorbed on the surface thereof, are formed so that they can be moved within the liquid by movement of the liquid or by a magnetic field, and promote a treatment for capturing or re-suspension of the magnetic carriers.

Abstract translation: 本发明涉及一种磁性试剂，磁性试剂盒，用于治疗的磁性载体的方法，以及一处理装置为此，与快速的对象和高效处理包括纳米尺寸的磁性载体微颗粒直径的磁载体。 磁性试剂或磁性试剂盒，包括：磁性载体的多个可以通过被暴露于磁场中磁化，可键合至在液体中的预定化学物质或生物体，并且也有一个颗粒直径确实使它们 被悬浮在液体中; 和治疗促销婷磁性颗粒的多个可以通过被暴露于磁场中磁化，因此可具有吸附在其表面上的磁性载体中，形成这样thatthey可以在液体内通过液体或通过移动而移动 一个磁场，并促进用于捕获或磁性载体的再悬浮的处理。

公开(公告)号：EP2439537A1

公开(公告)日：2012-04-11

申请号：EP10783462.4

申请日：2010-06-04

Applicant: Universal Bio Research Co., Ltd.

Inventor： TAJIMA Hideji

IPC: G01N35/00 ,  C12M1/34 ,  C12Q1/06 ,  G01N35/02

CPC classification number: G01N35/026 ,  G01N2035/0436

Abstract: The present invention relates to a specimen testing device and method thereof, and it is an object of the present invention to provide a compact and reliable specimen testing device and method thereof. The specimen testing device includes one, two or more test cartridge containers which comprise a plurality of accommodation parts which accommodate or can accommodate a specimen and one, two or more reagent solutions or testing tools used for testing the specimen, and which visibly display specimen information for identifying or managing the specimen and test information showing test content; an automatic testing unit which is attached with or supports the testing tools and which causes a reaction of the specimen and the reagent solution accommodated in the test cartridge containers to obtain a predetermined optical state; an optical measurement unit which measures the optical state obtained by the automatic testing unit; and a digital camera which captures an image of content including the specimen information and the test information and displayed on the one, two or more test cartridge containers to obtain image data.

Abstract translation: 试样检测装置及其方法技术领域本发明涉及试样检测装置及其方法，其目的在于提供一种紧凑可靠的试样检测装置及其方法。 样本测试装置包括一个，两个或更多个测试盒容器，其包括容纳或可容纳样本的多个容纳部分和用于测试样本的一个，两个或更多个试剂溶液或测试工具，并且可视地显示样品信息 用于识别或管理标本和测试显示测试内容的信息; 自动测试单元，其附接或支撑测试工具，并且引起样品和容纳在测试盒容器中的试剂溶液的反应以获得预定的光学状态; 光学测量单元，其测量由所述自动测试单元获得的光学状态; 以及数码相机，其捕获包括样本信息和测试信息的内容的图像，并显示在一个，两个或更多个测试盒容器上以获得图像数据。

公开(公告)号：EP4261546A1

公开(公告)日：2023-10-18

申请号：EP21906402.9

申请日：2021-12-06

Applicant: Universal Bio Research Co., Ltd.

Inventor： TAJIMA Hideji

IPC: G01N35/10

Abstract: A sample pooling system 1000 comprises a sample pooling device 200 that pools samples, a first PCR device 300 that performs a PCR on mixed samples, and a second PCR device 400 that performs a PCR on individual samples. The sample pooling device 200 comprises a single first rack 700a that accommodates a plurality of mixed sample containers in a row in the y direction; a plurality of second racks 700c that accommodate a plurality of individual sample containers in a row in the x direction; and a plurality of dispensation nozzles 240 that dispense a plurality of individual samples from the plurality of individual sample containers accommodated by a respective second rack 700c into a respective mixed sample container. The plurality of individual sample containers accommodated by one of the second racks 700c are aligned in the x direction with one of the plurality of mixed sample containers accommodated by the first rack 700a.

公开(公告)号：EP2679664B1

公开(公告)日：2019-10-09

申请号：EP11859097.5

申请日：2011-08-19

Applicant: Universal Bio Research Co., Ltd.

Inventor： TAJIMA Hideji

IPC: C12M1/00 ,  C12M1/34 ,  C12M1/38 ,  G01N1/10 ,  G01N35/02

公开(公告)号：EP3502710A1

公开(公告)日：2019-06-26

申请号：EP17843499.9

申请日：2017-08-18

Applicant: Universal Bio Research Co., Ltd.

Inventor： TAJIMA Hideji ,  NAKAMURA Kazuhiro ,  SUGIYAMA Yu

IPC: G01N35/10 ,  B01J4/02 ,  B01L3/02 ,  G01N1/00

Abstract: The present invention relates to a dispensing cylinder, and a dispensing device and a dispensing treatment method using the dispensing cylinder. An object of the present invention is to provide a compact, easily handled, and highly accurate dispensing cylinder capable of performing a dispensing treatment for both a minute amount of liquid and a large amount of liquid using a single mechanism, and a dispensing device and a dispensing treatment method using the dispensing cylinder.
The dispensing cylinder includes: a cylinder having a cavity therein; a nozzle provided at one end of the cylinder, having a through hole communicating with the cavity and extending in an axial direction of the cavity, and making a dispensing tip attachable to an outside thereof; and a plunger provided so as to be slidable in the cavity in the axial direction. The cavity has a large diameter region having a large diameter inner peripheral surface and a small diameter region provided so as to be closer to a nozzle than the large diameter region and having a small diameter inner peripheral surface. The plunger has a thick shaft portion provided so as to be slidable in the large diameter region and a thin shaft portion protruding from a distal end of the thick shaft portion in the axial direction and provided so as to be slidable in the small diameter region.

公开(公告)号：EP2628786B1

公开(公告)日：2019-01-02

申请号：EP11832627.1

申请日：2011-10-14

Applicant: Universal Bio Research Co., Ltd.

Inventor： TAJIMA Hideji

IPC: C12M1/00 ,  C12N15/09 ,  C12Q1/68 ,  B01L3/02 ,  B01L7/00

公开(公告)号：EP3321669A1

公开(公告)日：2018-05-16

申请号：EP16824372.3

申请日：2016-07-07

Applicant: Universal Bio Research Co., Ltd.

Inventor： TAJIMA Hideji

IPC: G01N27/02 ,  G01N27/27 ,  G01N27/28 ,  G01N35/10

CPC classification number: G01N27/02 ,  G01N27/27 ,  G01N27/28 ,  G01N35/10

Abstract: The present invention relates to a device for electrical measurement of a target chemical substance, and a method therefor, and an object of the present invention is to provide a compact, inexpensive, and highly reliable device.
A device for electrical measurement of a target chemical substance includes : an electrode array element including a base, an electrode array section in which electrodes which are disposed on the base and to each of which a test substance is fixed or can be fixed are arrayed, and a terminal array section in which terminals disposed on the base so as to correspond to the electrodes and electrically connected to the electrodes are arrayed; a processing head having an electrode array element support section supporting the electrode array element detachably to make electrical connection to the terminals possible; a container group including a liquid storing section and a measurement container; a support section moving mechanism capable of relatively moving the electrode array element support section with respect to the container group; and a measurement section capable of measuring a signal generated by applying a predetermined voltage to a test substance fixed to each of the electrodes in the measurement container. The container group includes a storing section storing or capable of storing the electrode array element such that the electrode array element can be supported by the electrode array element support section due to the support section moving mechanism.

Abstract translation: 目标化学物质的电测量装置及其方法技术领域本发明涉及一种用于目标化学物质的电测量装置及其方法，并且本发明的目的是提供一种紧凑，廉价且高度可靠的装置。 目标化学物质的电测量装置包括：电极阵列元件，该电极阵列元件包括：基座;电极阵列部分，在该电极阵列部分中布置在基座上并且被测物质被固定或可以被固定的每个电极; 以及端子阵列部分，其中布置在基底上以便与电极对应并电连接到电极的端子排列; 具有电极阵列元件支撑部分的加工头，所述电极阵列元件支撑部分可拆卸地支撑所述电极阵列元件以与所述端子电连接; 包括液体储存部分和测量容器的容器组; 支撑部移动机构，其能够相对于所述容器组使所述电极阵列元件支撑部相对移动; 以及测量部分，能够测量通过向固定到测量容器中的每个电极的测试物质施加预定电压而产生的信号。 容器组包括存储或能够存储电极阵列元件的存储部分，使得电极阵列元件可以由于支撑部分移动机构而由电极阵列元件支撑部分支撑。