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公开(公告)号:EP2083848A1
公开(公告)日:2009-08-05
申请号:EP07815590.0
申请日:2007-11-21
Applicant: Melbourne Health
Inventor: JANE, Stephen M , ZHAO, Quan , RANK, Gerhard
IPC: A61K38/43 , A61K39/395 , A61P7/06
CPC classification number: C12N15/1137 , C12N2310/11 , C12N2310/12 , C12N2310/14 , C12Y201/01125
Abstract: The present invention relates generally to a method for the treatment of a hemoglobinopathic condition in mammalian subjects such as humans and medicaments useful for same.
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22.
公开(公告)号:KR101771851B1
公开(公告)日:2017-08-25
申请号:KR1020160057891
申请日:2016-05-12
Applicant: 서울대학교산학협력단
IPC: G01N33/68 , C12N9/10 , C07K14/47 , A61K31/366
CPC classification number: G01N33/68 , A61K31/366 , C07K14/4702 , C12N9/1007 , C12Y201/01125 , G01N33/5005 , G01N33/6854 , G01N2440/12 , G01N2500/00 , G01N2500/10
Abstract: 본원은핵내에서작용하는 AMPK-FOXO3a-SKP2 신호전달체계를표적으로하는자가포식조절방법, 또는자가포식조절제스크리닝방법을개시한다. 본원에따른방법은상기기전축을중심으로다양한수준에서자가포식조절문제로인한다양한질환의치료제개발에유용하게사용될수 있다.
Abstract translation: 本申请公开了靶向作用于细胞核中的AMPK-FOXO3a-SKP2信号系统的自泳调节方法或自泳电泳调节剂筛选方法。 根据本发明的方法可以有效地用于开发各种疾病的治疗剂,这是由于在机构轴线周围的各种级别的自动控制的问题。
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