公开(公告)号：US09274056B2

公开(公告)日：2016-03-01

申请号：US12315413

申请日：2008-12-03

Applicant: Robert Hudak ,  Ian Buchanan

Inventor： Robert Hudak ,  Ian Buchanan

IPC: G01N33/558 ,  G01N21/64 ,  G01N21/84 ,  G01N33/58

CPC classification number: G01N21/6428 ,  G01N21/645 ,  G01N21/8483 ,  G01N33/558 ,  G01N33/582 ,  G01N2201/062 ,  G01N2201/0693 ,  G01N2201/0696

Abstract: The present invention includes an assay method for detecting an analyte in a sample. The assay includes a solid surface such as a nitrocellulose membrane. It also includes providing a sample is applied to the solid surface and detecting the presence or absence of the analyte using a fluorescent label from a lanthanide label. The invention also includes a device for detecting the fluorescence in or on an assay test strip. The device includes a housing, a solid surface and an ultraviolet radiation emitting LED.

Abstract translation: 本发明包括用于检测样品中的分析物的测定方法。 该测定包括固体表面，例如硝酸纤维素膜。 它还包括提供将样品应用于固体表面并使用来自镧系元素标签的荧光标记来检测分析物的存在或不存在。 本发明还包括用于检测测定条带中或上的荧光的装置。 该装置包括壳体，固体表面和紫外线发射LED。

公开(公告)号：US20150330955A1

公开(公告)日：2015-11-19

申请号：US14713328

申请日：2015-05-15

Applicant: BRIGHAM YOUNG UNIVERSITY

Inventor： Paul B. Farnsworth ,  Sonika Sharma ,  H. Dennis Tolley ,  Milton L. Lee

IPC: G01N30/74 ,  G01N21/05

CPC classification number: G01N30/74 ,  G01N21/05 ,  G01N21/33 ,  G01N2021/0346 ,  G01N2201/0221 ,  G01N2201/0621 ,  G01N2201/0693

Abstract: A system and method for performing UV LED-based absorption detection for capillary liquid chromatography for detecting and quantifying compounds in a liquid, wherein a simplified system eliminates the need for a beam splitter and a reference cell by using a stable UV source, and power requirements are reduced, resulting in a portable and substantially smaller system with relatively low detection limits.

Abstract translation: 一种用于对毛细管液相色谱进行UV基于LED的吸收检测以检测和定量液体中的化合物的系统和方法，其中简化的系统通过使用稳定的UV源而消除了对分束器和参考电池的需要以及功率要求 被减少，导致具有相对较低检测限的便携式和基本上较小的系统。

公开(公告)号：US08436994B2

公开(公告)日：2013-05-07

申请号：US12930762

申请日：2011-01-15

Applicant: Martin M. Liphardt ,  Jeffrey S. Hale ,  Ping He ,  Galen L. Pfeiffer

Inventor： Martin M. Liphardt ,  Jeffrey S. Hale ,  Ping He ,  Galen L. Pfeiffer

IPC: G01J4/00

CPC classification number: G01N21/01 ,  G01N21/21 ,  G01N21/211 ,  G01N21/55 ,  G01N2021/151 ,  G01N2021/212 ,  G01N2021/213 ,  G01N2021/214 ,  G01N2201/021 ,  G01N2201/0693

Abstract: A sample investigation system (ES) in functional combination with an alignment system (AS), and methodology of enabling calibration and very fast, (eg. seconds), sample height, angle-of-incidence and plane-of-incidence adjustments, with application in mapping ellipsometer or the like systems.

Abstract translation: 与对准系统（AS）功能组合的样本调查系统（ES）以及启用校准和非常快速（例如秒），样本高度，入射角度和入射平面调整的方法，具有 映射椭偏仪等应用。

公开(公告)号：US20090103093A1

公开(公告)日：2009-04-23

申请号：US12313760

申请日：2008-11-25

Applicant: Martin M. Liphardt ,  Jeffrey S. Hale ,  Ping He ,  Galen L. Pfeiffer

Inventor： Martin M. Liphardt ,  Jeffrey S. Hale ,  Ping He ,  Galen L. Pfeiffer

IPC: G01N21/21

CPC classification number: G01N21/211 ,  G01N21/01 ,  G01N21/21 ,  G01N21/55 ,  G01N2021/151 ,  G01N2021/212 ,  G01N2021/213 ,  G01N2021/214 ,  G01N2201/021 ,  G01N2201/0693

Abstract: A sample investigation system (ES) in functional combination with an alignment system (AS), and methodology of enabling very fast, (eg. seconds), sample height, angle-of-incidence and plane-of-incidence adjustments, with application in mapping ellipsometer or the like systems.

Abstract translation: 与对准系统（AS）功能组合的样本调查系统（ES）以及启用非常快速（例如秒），样本高度，入射角度和入射平面调整的方法，应用于 映射椭偏仪等。

公开(公告)号：US20070247844A1

公开(公告)日：2007-10-25

申请号：US11695894

申请日：2007-04-03

Applicant: Jack Brass ,  Richard Doran ,  Donald Klipstein ,  Thomas Lemons ,  Bjarki Hallgrimson ,  Sarah Dobbin

Inventor： Jack Brass ,  Richard Doran ,  Donald Klipstein ,  Thomas Lemons ,  Bjarki Hallgrimson ,  Sarah Dobbin

IPC: F21V9/00

CPC classification number: G01N21/6428 ,  G01N21/31 ,  G01N21/6402 ,  G01N21/6447 ,  G01N21/8803 ,  G01N2201/0221 ,  G01N2201/0612 ,  G01N2201/0621 ,  G01N2201/0627 ,  G01N2201/0638 ,  G01N2201/0693 ,  Y10S362/80

Abstract: An LED inspection lamp has plurality of LED sources for emitting electromagnetic radiation at different peak wavelengths for causing visible fluorescence in different leak detection dyes. A lens is associated with each LED. Radiation passing through lenses is superimposed in target area at target distance. Another LED inspection lamp has plurality of LEDs emitting electromagnetic radiation at a peak wavelength. A lens adaptor has lens housing for attachment to LED inspection lamp with a single LED for causing visible fluorescence, and a lens. Substantially all of the radiation from the LED passes through the lens and is focused in a target area at a target distance from the lenses. LED spot lights have a similar configuration. The LEDs may produce white light from distinct LEDs or from white LEDs. The light may be a flashlight or fixed spot light.

Abstract translation: LED检查灯具有多个LED源，用于发射不同峰值波长的电磁辐射，以引起不同的检漏染料中的可见荧光。 镜头与每个LED相关联。 通过透镜的辐射以目标距离叠加在目标区域中。 另一个LED检查灯具有发射峰值波长的电磁辐射的多个LED。 镜头适配器具有透镜壳体，用于附接到具有用于引起可见荧光的单个LED的LED检查灯和透镜。 基本上来自LED的所有辐射通过透镜并聚焦在与透镜目标距离处的目标区域中。 LED射灯具有相似的配置。 LED可能产生来自不同LED或白色LED的白光。 灯可能是手电筒或固定点灯。

公开(公告)号：US07198755B2

公开(公告)日：2007-04-03

申请号：US10241451

申请日：2002-09-12

Applicant: Eugene Tokhtuev ,  Anatoly Skirda ,  Viktor Slobodyan ,  Christopher Owen

Inventor： Eugene Tokhtuev ,  Anatoly Skirda ,  Viktor Slobodyan ,  Christopher Owen

IPC: G01N21/00 ,  G01N21/75 ,  G01N21/62 ,  G01N21/76 ,  B32B5/02

CPC classification number: G01N21/8507 ,  G01N21/15 ,  G01N21/274 ,  G01N21/276 ,  G01N21/645 ,  G01N33/1886 ,  G01N2021/6417 ,  G01N2021/6421 ,  G01N2021/6478 ,  G01N2201/0218 ,  G01N2201/024 ,  G01N2201/0627 ,  G01N2201/0693 ,  Y10T436/11

Abstract: A multichannel fluorosensor includes an optical module and an electronic module combined in a watertight housing with an underwater connector. The fluorosensor has an integral calibrator for periodical sensitivity validation of the fluorosensor. The optical module has one or several excitation channels and one or several emission channels that use a mutual focusing system. To increase efficiency, the excitation and emission channels each have a micro-collimator made with one or more ball lenses. Each excitation channel has a light emitting diode and an optical filter. Each emission channel has a photodiode with a preamplifier and an optical filter. The electronic module connects directly to the optical module and includes a lock-in amplifier, a power supply and a controller with an A/D converter and a connector. The calibrator provides a response proportional to the excitation intensity, and matches with spectral parameter of fluorescence for the analyzed fluorescent substance.

Abstract translation: 多通道氟传感器包括光学模块和组合在具有水下连接器的防水壳体中的电子模块。 氟传感器具有用于氟传感器周期灵敏度验证的积分校准器。 光学模块具有一个或多个激发通道和使用相互聚焦系统的一个或多个发射通道。 为了提高效率，激发和发射通道各自具有由一个或多个球透镜制成的微型准直器。 每个激励通道都有一个发光二极管和一个滤光器。 每个发射通道具有带有前置放大器和光学滤波器的光电二极管。 电子模块直接连接到光模块，包括锁定放大器，电源和带有A / D转换器和连接器的控制器。 校准器提供与激发强度成比例的响应，并与分析的荧光物质的荧光光谱参数相匹配。

公开(公告)号：US5519219A

公开(公告)日：1996-05-21

申请号：US303174

申请日：1994-09-08

Applicant: Christopher C. Alexay ,  William L. Truett ,  Christopher D. Prozzo ,  Barry O'Dwyer

Inventor： Christopher C. Alexay ,  William L. Truett ,  Christopher D. Prozzo ,  Barry O'Dwyer

IPC: G01N21/35 ,  G01N21/25

CPC classification number: G01N21/3504 ,  G01N21/3563 ,  G01N21/3577 ,  G01N2201/0221 ,  G01N2201/0693

Abstract: There is described within a portable, battery-powered multiple filter infrared spectrometer consisting of a highly efficient optical system employing an infrared source with a chopper, from which IR energy passes through compound parabolic concentrators (CPC's) and is directed by a beamsplitter to the external sample, where the beam intersects with the sample via reflection and is returned through the CPC and beamsplitter to a stationary filter assembly and discrete detector array where the energy is converted to an A.C. (alternating current) signal. This current energizes an LED bar graph display for spectral identification. This method and apparatus is used to determine IR spectra of solids, liquids on a mirror, and gases in a container with a mirror to reflect light.

Abstract translation: 在由便携式电池供电的多重滤波器红外光谱仪中描述，其包括使用具有斩光器的红外源的高效光学系统，IR能量通过复合抛物面聚光器（CPC）并由分束器引导到外部 样品，其中光束通过反射与样品相交，并通过CPC和分束器返回到固定的过滤器组件和离散检测器阵列，其中能量被转换为AC（交流）信号。 该电流激励LED条形图显示以进行光谱识别。 该方法和装置用于确定固体，反射镜上的液体和具有反射光的反射镜的容器中的气体的IR光谱。

公开(公告)号：WO2008024080A1

公开(公告)日：2008-02-28

申请号：PCT/SG2007/000272

申请日：2007-08-24

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH ,  NEUZIL, Pavel ,  PIPPER, Juergen ,  NOVAK, Lukas

Inventor： NEUZIL, Pavel ,  PIPPER, Juergen ,  NOVAK, Lukas

IPC: G01N21/64 ,  G01N33/533

CPC classification number: G01N21/645 ,  B01L3/5088 ,  B01L7/52 ,  B01L2200/147 ,  B01L2300/1827 ,  G01N21/0332 ,  G01N21/6428 ,  G01N21/76 ,  G01N21/763 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2201/0221 ,  G01N2201/0625 ,  G01N2201/0627 ,  G01N2201/0693

Abstract: A detection system is provided, the detection system comprising a light source that generates excitation light having a wavelength sufficient to excite a fluorophore in a sample; an excitation filter positioned along a first line along a path of the excitation light, the excitation filter transmitting the excitation light from the light source; a beam splitter positioned along the first line, the beam splitter reflecting the excitation light transmitted by the excitation filter along a second line toward a mirror positioned on one side of the beam splitter, and passing emitted light reflected along the second line; the mirror, positioned to reflect the excitation light from the beam splitter to the fluorophore in the sample along a third line, normal to both the first and second lines, wherein the mirror further reflects emitted light emitted along the third line, along the second line toward the beam splitter; an emission filter positioned along the second line, on a second side of the beam splitter; and a detector that detects the emitted light transmitted by the emission filter.

Abstract translation: 提供一种检测系统，所述检测系统包括产生具有足以激发样品中的荧光团的波长的激发光的光源; 激励滤光器，其沿着激励光的路径沿着第一线定位，所述激发滤光器透射来自所述光源的激发光; 分束器，沿着第一线定位，分束器将由激励滤光器透射的激发光沿着第二线反射到位于分束器一侧的反射镜，并且使沿着第二线反射的发射光反射; 所述反射镜被定位成将来自分束器的激发光沿着垂直于第一和第二线的第三线反射到样品中的荧光团，其中所述反射镜还沿着第二线反射沿着第三线发射的发射光 朝向分束器; 沿着所述第二线定位在所述分束器的第二侧上的发射滤光器; 以及检测由发射滤波器发射的发射光的检测器。

公开(公告)号：WO2007070275A9

公开(公告)日：2007-08-02

申请号：PCT/US2006046165

申请日：2006-12-05

Applicant: ECOLAB INC ,  TOKHTUEV EUGENE

Inventor： TOKHTUEV EUGENE ,  SKIRDA ANATOLY ,  SLOBODYAN VIKTO ,  OWEN CHRISTOPHER

IPC: G01N21/93 ,  G01N21/15 ,  G01N21/27 ,  G01N21/64 ,  G01N33/18

CPC classification number: G01N21/645 ,  G01N21/15 ,  G01N21/276 ,  G01N21/278 ,  G01N21/6486 ,  G01N21/8507 ,  G01N33/1826 ,  G01N2021/6417 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6478 ,  G01N2201/0218 ,  G01N2201/024 ,  G01N2201/0627 ,  G01N2201/0693 ,  Y10T29/49 ,  Y10T29/49002 ,  Y10T436/108331

Abstract: A multichannel fluorosensor includes an optical module and an electronic module combined in a watertight housing with an underwater connector. The fluorosensor has an integral calibrator for periodical sensitivity validation of the fluorosensor. The optical module has one or several excitation channels and one or several emission channels that use a mutual focusing system. To increase efficiency, the excitation and emission channels each have a micro-collimator made with one or more ball lenses. Each excitation channel has a light emitting diode and an optical filter. Each emission channel has a photodiode with a preamplifier and an optical filter. The electronic module connects directly to the optical module and includes a lock-in amplifier, a power supply and a controller with an A/D converter and a connector. The calibrator provides a response proportional to the excitation intensity, and matches with spectral parameter of fluorescence for the analyzed fluorescent substance.

Abstract translation: 多通道氟传感器包括光学模块和组合在具有水下连接器的防水壳体中的电子模块。 氟传感器具有用于氟传感器周期灵敏度验证的积分校准器。 光学模块具有一个或多个激发通道和使用相互聚焦系统的一个或多个发射通道。 为了提高效率，激发和发射通道各自具有由一个或多个球透镜制成的微型准直器。 每个激励通道都有一个发光二极管和一个滤光器。 每个发射通道具有带有前置放大器和光学滤波器的光电二极管。 电子模块直接连接到光模块，包括锁定放大器，电源和带有A / D转换器和连接器的控制器。 校准器提供与激发强度成比例的响应，并与分析的荧光物质的荧光光谱参数相匹配。

公开(公告)号：WO1989003524A1

公开(公告)日：1989-04-20

申请号：PCT/US1988000523

申请日：1988-02-29

Applicant: ELECTRONIC INSTRUMENTATION AND TECHNOLOGY, INC.

Inventor： ELECTRONIC INSTRUMENTATION AND TECHNOLOGY, INC. ,  MAY, Joe, T. ,  CASACIA, Edward, A.

IPC: G01N21/59

CPC classification number: G01N21/251 ,  G01J1/1626 ,  G01J2001/161 ,  G01N21/8507 ,  G01N2201/0693 ,  G01N2201/12761

Abstract: A portable, battery powered instrument for measuring the amount of material dissolved in a liquid solution employs electro-optic technology based on the Beer-Lambert Law. A sample probe (14) is inserted in a solution to be measured. The results of the measurement are displayed on a display (22). The displayed results are frozen for a predetermined period of time at the expiration of which, the power is turned off to conserve battery power.

Abstract translation: 用于测量溶解在液体溶液中的材料量的便携式电池供电仪器采用基于Beer-Lambert法的电光技术。 将样品探针（14）插入待测溶液中。 测量结果显示在显示器（22）上。 显示的结果被冻结预定的时间段，在此期间电源被关闭以节省电池电力。