公开(公告)号：US20230314334A1

公开(公告)日：2023-10-05

申请号：US18011521

申请日：2021-06-15

Applicant: VIENEX CORPORATION

Inventor： Osamu IWASAKI ,  Yoshihiro KAGAWA

IPC: G01N21/88 ,  H04N25/701 ,  H04N23/56 ,  G01N21/94

CPC classification number: G01N21/8806 ,  H04N25/701 ,  G01N2201/0826 ,  G01N21/94 ,  G01N2201/0633 ,  H04N23/56

Abstract: One pixel unit including at least one light receiving element of a light receiving element array (photodiode array) and a light source have a one-to-one correspondence, and only when the light source emits light, the light beam is detected by at least one light receiving element (one pixel unit) corresponding to the light source. An illumination optical system includes a light guiding means for guiding to an inspection object by reducing an interval between optical axes of light beams emitted from a plurality of light sources in an arrangement direction of a plurality of the light sources.

公开(公告)号：US11766176B2

公开(公告)日：2023-09-26

申请号：US17410206

申请日：2021-08-24

Applicant: The General Hospital Corporation

Inventor： Seemantini K. Nadkarni

IPC: A61B5/00 ,  A61B5/02 ,  G01N21/47 ,  G01N21/49 ,  F21V8/00 ,  G02B23/24 ,  G02B23/26

CPC classification number: A61B5/0084 ,  A61B5/0062 ,  A61B5/02007 ,  A61B5/02028 ,  A61B5/6853 ,  A61B5/6869 ,  A61B5/6876 ,  A61B5/7203 ,  A61B5/7275 ,  G01N21/474 ,  G01N21/4788 ,  G01N21/49 ,  G02B6/0005 ,  G02B23/2453 ,  G02B23/26 ,  G01N2021/479 ,  G01N2021/4742 ,  G01N2201/0683 ,  G01N2201/08 ,  G01N2201/0826

Abstract: An apparatus for obtaining information regarding a biological structure(s) can include, for example a light guiding arrangement which can include a fiber through which an electromagnetic radiation(s) can be propagated, where the electromagnetic radiation can be provided to or from the structure. An at least partially reflective arrangement can have multiple surfaces, where the reflecting arrangement can be situated with respect to the optical arrangement such that the surfaces thereof each can receive a(s) beam of the electromagnetic radiations instantaneously, and a receiving arrangement(s) which can be configured to receive the reflected radiation from the surfaces which include speckle patterns.

公开(公告)号：US20230251192A1

公开(公告)日：2023-08-10

申请号：US18299408

申请日：2023-04-12

Applicant: Georgia Tech Research Corporation

Inventor： Francisco Robles ,  Patrick Ledwig

IPC: G01N21/41 ,  G01N33/483 ,  G02B21/06 ,  G02B21/36 ,  G06V20/69

CPC classification number: G01N21/41 ,  G01N33/4833 ,  G02B21/06 ,  G02B21/365 ,  G06V20/693 ,  G06V20/698 ,  G01N2021/418 ,  G01N2201/061 ,  G01N2201/062 ,  G01N2201/0826

Abstract: Systems and methods for imaging cells. Quantitative phase imaging uses variations in the index of refraction of a sample as a source of endogenous contrast, providing label-free information of sub-cellular structures and allowing for the reconstruction of valuable biophysical parameters, such as cell dry-mass at femtogram scales, mass transport, and sample thickness and fluctuations at nanometer scales. As a result, QPI has become a valuable tool in biology and medicine. However, QPI has suffered from the need for trans-illumination through relatively thin objects in order to gain access to the forward-scattered field, which carries crucial low spatial frequency information of a sample and avoid contributions from multiple scattered light or out-of-focus planes. The disclosed methods and systems can provide for reconstruction of QPI and corresponding analysis for imaging samples of cells in thick samples using an epi-illumination configuration.

公开(公告)号：US10024799B2

公开(公告)日：2018-07-17

申请号：US15122170

申请日：2015-02-13

Applicant: INDIAN INSTITUTE OF SCIENCE

Inventor： Siva Umapathy ,  Sanchita Sil ,  Gagan Dhal ,  Freek Ariese

IPC: G01J3/44 ,  G01N21/65 ,  G01B11/00 ,  G01J3/02

CPC classification number: G01N21/65 ,  G01B11/00 ,  G01J3/0221 ,  G01J3/027 ,  G01J3/0289 ,  G01J3/44 ,  G01J3/4412 ,  G01N21/4795 ,  G01N2201/0221 ,  G01N2201/06113 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: The invention provides a method for chemical signature resolved detection of a concealed object within a system. The method includes irradiating the system at a plurality of positions with aplurality of electromagnetic radiation of specific wavelength; capturing a certain component of the scattered electromagnetic radiation from the object at a plurality of locations along various 3D planes around the system; obtaining a plurality of profiles from the captured component of the scattered electromagnetic radiation; filtering the profiles to obtain a chemical signature specific to the object; and resolving the chemical signatures to detect the concealed object, wherein, the step of detection includes determination of the shape, size and location of the object.

公开(公告)号：US20180164212A1

公开(公告)日：2018-06-14

申请号：US15812475

申请日：2017-11-14

Applicant: VALMET AUTOMATION OY

Inventor： Pasi KÄRKI ,  Matti TÖRMÄNEN

IPC: G01N21/53 ,  G01N33/34

CPC classification number: G01N21/532 ,  G01N21/33 ,  G01N21/474 ,  G01N21/53 ,  G01N21/85 ,  G01N33/343 ,  G01N2021/475 ,  G01N2021/4769 ,  G01N2021/8592 ,  G01N2201/0826

Abstract: A solution for measuring a suspension which contains wood fibres. The consistency of the suspension is changed in a consistency range. Optical radiation is directed at the suspension and the intensity of optical radiation interacted with the suspension is measured at different consistencies in the consistency range. The maximum intensity of the optical radiation is determined within the consistency range. At least one of the following properties of the suspension are determined based on the determined maximum intensity: kappa number, brightness.

公开(公告)号：US20180100800A1

公开(公告)日：2018-04-12

申请号：US15805123

申请日：2017-11-06

Applicant: KUANTAG NANOTEKNOLOJILER GELISTIRME VE URETIM A.S. ,  KOC UNIVERSITESI

Inventor： HAKAN UREY ,  OSMAN VEDAT AKGUN ,  EMRE HEVES ,  FEHMI CIVITCI ,  BASARBATU CAN

IPC: G01N21/64 ,  G01N21/85

CPC classification number: G01N21/643 ,  G01N21/645 ,  G01N21/8507 ,  G01N2021/6421 ,  G01N2021/6484 ,  G01N2201/0624 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: In the present invention, a fluorescent substance detection system (S) for detecting fluorescent substances in any environment is provided. Said detection system (S) comprises at least one illumination unit (1) which emits light to said environment in order to excite said substances; detection units (2), at least at a number equal to the number of types of fluorescent substances, for detecting emissions coming from said excited fluorescent substances and bandpass filters (3), each connected to detection units (2) one by one, wherein bandpass filters (3) have a center wavelength matched to the center emission wavelength of corresponding fluorescent substance.

公开(公告)号：US09921149B2

公开(公告)日：2018-03-20

申请号：US15027536

申请日：2015-04-24

Applicant: Otsuka Electronics Co., Ltd.

Inventor： Tsutomu Mizuguchi

IPC: G01N33/00 ,  G01N21/27 ,  G01N21/25

CPC classification number: G01N21/27 ,  G01N21/255 ,  G01N21/8422 ,  G01N33/00 ,  G01N2021/8411 ,  G01N2033/0096 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: A controller of an optical measurement apparatus causes, in a condition that a rotational speed of a rotary body is controlled so that the speed is a specified value, a light source to generate light having a constant intensity and apply the light to an irradiation region, and acquires first timing information based on a change with time of an intensity of reflected light or transmitted light that is output from a second detection unit receiving the reflected light or transmitted light of the applied light. The controller causes the light source to periodically generate pulsed light in accordance with the first timing information and apply the pulsed light to the irradiation region, and acquires second timing information based on a result which is output from the first detection unit whose measurement is periodically enabled in accordance with the first timing information.

公开(公告)号：US20170363471A1

公开(公告)日：2017-12-21

申请号：US15624008

申请日：2017-06-15

Applicant: Metal Power Analytical (I) Pvt. Ltd.

Inventor： Priyadarshan Divyadarshan PANT

IPC: G01J3/06 ,  G01J3/28 ,  G01N21/31 ,  G01N21/33 ,  G01J3/02 ,  G01J3/04 ,  G01J3/443

CPC classification number: G01J3/06 ,  G01J3/0218 ,  G01J3/0232 ,  G01J3/04 ,  G01J3/18 ,  G01J3/2803 ,  G01J3/32 ,  G01J3/443 ,  G01J2003/045 ,  G01J2003/061 ,  G01J2003/065 ,  G01J2003/282 ,  G01N21/3103 ,  G01N21/33 ,  G01N2201/0826

Abstract: The present disclosure relates to the field of optical systems. The envisaged multi-scan optical system is compact and stable. The system comprises an excitation source, a hydra fiber cable, a wavelength selector, an optical element, and a detector. The excitation source is configured to emit composite light. The hydra fiber cable has a head and a plurality of tentacles, and is configured to receive the composite light via a second lens. The plurality of tentacles is configured to emit the composite light towards the wavelength selector which includes a plurality of optical slits (s1-s8) and a plurality of shutters. The wavelength selector is configured to selectively collect and filter the composite light directed by a first lens and the plurality of tentacles by means of the plurality of shutters. The detector is configured to detect the plurality of spectral line scans reflected by the optical element for spectrometric analysis.

公开(公告)号：US09833147B2

公开(公告)日：2017-12-05

申请号：US14361428

申请日：2012-11-09

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Toshihiko Suzuki ,  Yutaka Yamashita ,  Yukio Ueda ,  Etsuko Yamaki ,  Daisuke Yamashita ,  Kenji Yoshimoto ,  Harumi Sakahara ,  Hiroyuki Ogura ,  Hatsuko Nasu

IPC: A61B5/00 ,  A61B8/08 ,  A61B8/00 ,  G01N21/47

CPC classification number: A61B5/0091 ,  A61B5/0035 ,  A61B5/708 ,  A61B8/0825 ,  A61B8/4416 ,  A61B2562/046 ,  A61B2562/146 ,  A61B2562/168 ,  G01N21/4795 ,  G01N2021/4797 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: A mammography device is disclosed. The mammography device includes a container configured to surround the breast and a plurality of optical fibers attached to be directed inward in the container and configured to perform radiation and detection of light. The container has a base member having an opening, a plurality of annular members continuously disposed to come in communication with the opening, and a bottom member disposed inside the annular member spaced the farthest distance from the base member. The annular members and the bottom member are configured to relatively displace the adjacent annular member on the side of the base member or the base member in a communication direction. Some of the plurality of optical fibers is attached to the plurality of annular members.

公开(公告)号：US20170115217A1

公开(公告)日：2017-04-27

申请号：US14923998

申请日：2015-10-27

Applicant: Laxco Inc.

Inventor： Congliang Chen ,  Kevin Cassady

IPC: G01N21/59 ,  G01N21/27

CPC classification number: G01N21/59 ,  G01N21/0303 ,  G01N21/27 ,  G01N2021/035 ,  G01N2021/036 ,  G01N2201/0826

Abstract: This disclosure relates generally to analytical instruments for measuring one or more properties of specimens or samples to be analyzed and, more particularly, to an analytical instrument with an adjustable optical path length. An analytical instrument may include a specimen support upon which a specimen may rest and a compression plate for controllably adjusting an optical path length of the specimen between the specimen support and the compression plate. In particular, a specimen may contact both the specimen support and the compression plate such that controlling a distance of the compression plate with respect to the specimen support effectively controls the optical path length of the specimen. An analytical instrument may include collimating lenses to collimate electromagnetic energy for transmission through a specimen and converging lenses for directing electromagnetic energy transmitted through the specimen into one or more sensors.