Abstract:
A microfluidic device is formed from a cover member and a microfluidic precursor that is prepared from a photosensitive element. The photosensitive element is a solid layer of a photopolymerizable composition that includes at least a binder, a monomer, and a photoinitiator. A method for forming the microfluidic device from the photosensitive element includes imagewise exposing the photopolymerizable layer to actinic radiation through a mask and treating to form a relief surface having microstructures or features, such as one or more channels and one or more chambers, that are suitable for use in the microfluidic device. The method provides microstructures that can be formed to have different dimensions that provide particular advantages for a microfluidic device that is operated by degas-driven flow to transport a fluid through the microstructures.
Abstract:
Die Erfindung betrifft ein mikrofluidisches Bauteil aus einem Blech mit einer eine geschlossene Fluidleitung umfassenden Struktur, die aus einer strukturierten Oberfläche eines ersten Abschnitts des Bleches und einer angrenzenden strukturierten oder unstrukturierten Oberfläche eines zweiten Abschnitts des Bleches gebildet wird, wobei das Blech derart gefaltet ist, dass die einstückig zusammenhängenden Abschnitte flächenparallel aufeinanderliegen. Ferner weist das Blech wenigstens einen dritten Abschnitt mit einer konturierten Kante auf und ist weiterhin derart gefaltet, dass auch der dritte Abschnitt flächenparallel aufliegt und die konturierte Kante einen ersten Wandabschnitt und die angrenzende strukturierte oder unstrukturierte Oberfläche des ersten oder zweiten Abschnitts einen zweiten Wandabschnitt einer offenen Fluidleitung bilden. Die Erfindung betrifft ferner einen mikrofluidischen Reaktor aus mehreren solchen mikrofluidischen Bauteilen und Verfahren zur Herstellung derselben.
Abstract:
A method is provided for fabricating a fluidic module (80) comprising fluidic channels (60) defined within a glass or glass-ceramic structure. According to the method, a heterogeneous channel-forming laminate (10) is provided comprising a mold-engaging layer (20) and a laminate backbone (30). The laminate backbone (30) comprises a vitreous body defining a supportive viscosity µ B . A channel-forming mold (50) is pressed into engagement with the mold-engaging layer (20) of the channel forming laminate (10) at a molding temperature T M to form fluidic channel components (40) in the channel-forming laminate (10). The molding viscosity µ M of the mold-engaging layer (20) is less than the supportive viscosity µB of the laminate backbone (30) at the molding temperature T M . The pressed channel-forming laminate (10') is stacked with a plurality of complementary pressed channel forming laminates (10') to define a plurality of fluidic channels (60) in a stacked laminate structure (70). The plurality of fluidic channels (60) in the stacked laminate structure (70) is sealed at a sealing temperature T S that is less than the molding temperature T M and above a softening point temperature of the mold-engaging layer (20). Fluidic modules (80) comprising a stacked laminate structure (70) are also provided.
Abstract:
A photostructurable ceramic is processed using photostructuring process steps for embedding devices within a pholostruclurable ceramic volume, the devices may include one or more of chemical, mechanical, electronic, electromagnetic, optical, and acoustic devices, all made in part by creating device material within the ceramic or by disposing a device material through surface ports of the ceramic volume, with the devices being interconnected using internal connections and surface interfaces.
Abstract:
A reactor comprising a platform, the platform at least defining: at least one fluid reservoir arranged to receive fluid; a plurality of reaction chambers, wherein the reaction chambers are discrete from each other; a plurality of supply channels for transporting fluid from the at least one fluid reservoir to one or more of the plurality of reaction chambers; pumping means arranged to pump fluid through one or more of a plurality of supply channels.A method of manufacturing the reactor, and the use of the reactor and a kit comprising the reactor.
Abstract:
Disclosed is a micro-nano fluidic biochip for assaying a biological sample comprising a first substrate, a second substrate and a third substrate which are sequentially stacked from bottom to top, wherein an upper channel assembly disposed on the second substrate is coupled with the lower channel assembly provided on the first substrate, to form a microfluidic channel, and the microfluidic channel has nano interstices formed at both sides thereof, the nano interstices having a height less than that of the center of the channel.
Abstract:
A MEM device has a rigid body (30, 40, 60, 170, 250) and an actuator in the form of a flexible film (15, 50), able to move between a rolled up state away from the rigid body and a rolled out state against the rigid body, by a controllable driving force which causes an attraction of rolled up parts of the flexible film to the rigid body. The rigid body or the flexible film are patterned so that a given level of driving provides an attraction which differs at different parts of the pattern. By patterning to enable non uniform attraction at different parts, a range of attractions which could cause release of a given part of the film can be made narrower and thus more predictable. Thus the drive force needed to achieve initial separation can be controlled, or the roll up can be held stably at an intermediate point.
Abstract:
Disclosed is a micro-nano fluidic biochip for assaying a biological sample comprising a first substrate, a second substrate and a third substrate which are sequentially stacked from bottom to top, wherein an upper channel assembly disposed on the second substrate is coupled with the lower channel assembly provided on the first substrate, to form a microfluidic channel, and the microfluidic channel has nano interstices formed at both sides thereof, the nano interstices having a height less than that of the center of the channel.