Methods of differentiating and protecting cells by modulating the P38/MEF2 pathway
    361.
    发明授权
    Methods of differentiating and protecting cells by modulating the P38/MEF2 pathway 有权
    通过调节P38 / MEF2途径分化和保护细胞的方法

    公开(公告)号:US07919317B2

    公开(公告)日:2011-04-05

    申请号:US09876187

    申请日:2001-06-05

    Abstract: The present invention provides a method of differentiating progenitor cells to produce a population containing protected neuronal cells. A method of the invention includes the steps of contacting the progenitor cells with a differentiating agent; and introducing into the progenitor cells a nucleic acid molecule encoding a MEF2 polypeptide or an active fragment thereof, thereby differentiating the progenitor cells to produce a population containing protected neuronal cells. In one embodiment, the MEF2 polypeptide is human MEF2C or an active fragment thereof.

    Abstract translation: 本发明提供了一种区分祖细胞以产生含有受保护的神经元细胞的群体的方法。 本发明的方法包括使祖细胞与分化剂接触的步骤; 并且向祖细胞中引入编码MEF2多肽或其活性片段的核酸分子,由此分化祖细胞以产生含有受保护的神经元细胞的群体。 在一个实施方案中,MEF2多肽是人MEF2C或其活性片段。

    System and method for supporting standard and voltage optimized DIMMs
    362.
    发明授权
    System and method for supporting standard and voltage optimized DIMMs 有权
    支持标准和电压优化的DIMM的系统和方法

    公开(公告)号:US07876592B2

    公开(公告)日:2011-01-25

    申请号:US12327292

    申请日:2008-12-03

    Inventor: Stuart A. Berke

    CPC classification number: G11C5/04 G11C5/147

    Abstract: A device includes a dynamic random access memory and a voltage regulator. The dynamic random access memory has a first input terminal connected to a first plurality of dual in-line memory module voltage pins, and a second input terminal. The dynamic random access memory is configured to receive a first voltage on the first input terminal. The voltage regulator has an input terminal connected to a second plurality of dual in-line memory module voltage pins, and an output terminal connected to the second input terminal of the dynamic random access memory. The voltage regulator is adapted to receive a second voltage, and configured to provide a third voltage to the second input terminal of the dynamic random access memory.

    Abstract translation: 一种设备包括动态随机存取存储器和电压调节器。 动态随机存取存储器具有连接到第一多个双列直插存储器模块电压引脚的第一输入端和第二输入端。 动态随机存取存储器被配置为在第一输入端子上接收第一电压。 电压调节器具有连接到第二多个双列直插存储器模块电压引脚的输入端子和连接到动态随机存取存储器的第二输入端子的输出端子。 电压调节器适于接收第二电压,并且被配置为向动态随机存取存储器的第二输入端提供第三电压。

    ROD CHANGER FOR A ROCK DRILL
    364.
    发明申请
    ROD CHANGER FOR A ROCK DRILL 审中-公开
    ROD钻机的更换

    公开(公告)号:US20100307826A1

    公开(公告)日:2010-12-09

    申请号:US12792340

    申请日:2010-06-02

    CPC classification number: E21B19/146 E21B7/025

    Abstract: A rock drill system includes a rotatable carousal adapted to hold a plurality of drill rods. A carousal driver is in communication with the rotatable carousal. The carousal driver includes a driver gear and a driven gear. Both the driver gear and the driven gear are coated with a self-lubricating/anti-corrosive layer comprising a metal-containing composition and a fluorine-containing resin. The rock drill system also includes a rod gripper for positioning a drill rod under a rock drill. Another rock drill system of similar design is provided in which the rod gripper includes one or more pivot pins that are coated with a self-lubricating/anti-corrosive layer comprising a metal-containing composition and a fluorine-containing resin.

    Abstract translation: 凿钻系统包括适于保持多个钻杆的可旋转转盘。 转盘驱动器与可旋转转盘通信。 转盘驱动器包括驱动齿轮和从动齿轮。 驱动齿轮和从动齿轮都涂覆有包含含金属组合物和含氟树脂的自润滑/防腐蚀层。 凿钻系统还包括用于将钻杆定位在凿岩机下方的杆夹持器。 提供了类似设计的另一种凿岩系统,其中杆夹持器包括一个或多个枢轴销,该枢轴销被包含含有金属的组合物和含氟树脂的自润滑/防腐蚀层。

    SYSTEM AND METHOD THAT PROVIDE INCENTIVES TO QUALIFIED USERS OF AN ELECTRONIC TRADING SYSTEM
    365.
    发明申请
    SYSTEM AND METHOD THAT PROVIDE INCENTIVES TO QUALIFIED USERS OF AN ELECTRONIC TRADING SYSTEM 有权
    向电子交易系统的合格用户提供激励的系统和方法

    公开(公告)号:US20100306042A1

    公开(公告)日:2010-12-02

    申请号:US12852762

    申请日:2010-08-09

    Abstract: Systems and methods for electronic trading that provide incentives to users of a trading system. The systems and methods may monitor a trading activity of the user and determine that the orders submitted by the user over a period of time exceed a first pre-determined threshold. Systems and methods also determine that a spread of the plurality of orders exceeds a second pre-determined threshold. Based on these determinations, the user is designated as qualifying for a special status, which entitles the user to incentives in trading. Systems and methods apply the incentives to an order submitted by the user. One such incentive provides the user with a priority in a trading queue, where orders submitted by the user are executed in advance of other orders in the trading queue.

    Abstract translation: 电子交易的系统和方法,为交易系统的用户提供激励。 系统和方法可以监视用户的交易活动并确定用户在一段时间内提交的订单超过第一预定阈值。 系统和方法还确定多个订单的扩展超过第二预定阈值。 根据这些决定,用户被指定为符合资格的特殊状态,这有助于用户在交易中获得激励。 系统和方法将激励措施应用于用户提交的订单。 一种这样的激励措施使用户在交易队列中具有优先权,其中由用户提交的订单在交易队列中的其他订单之前执行。

    4+ COLOR MANAGEMENT FOR GAMUT EXTENSION USING A VIRTUAL CMYK METHODOLOGY
    366.
    发明申请
    4+ COLOR MANAGEMENT FOR GAMUT EXTENSION USING A VIRTUAL CMYK METHODOLOGY 有权
    4+使用虚拟CMYK方法进行游戏扩展的颜色管理

    公开(公告)号:US20100284029A1

    公开(公告)日:2010-11-11

    申请号:US12463469

    申请日:2009-05-11

    CPC classification number: H04N1/6058 H04N1/54

    Abstract: 4+ color management sequentially processes four colors at a time from among the 4+ colors to leverage solution capability using a 4-color management tools. In methods and apparatus for processing 4+ colors, received information of 4+ colors may be processed in a first stage using four colors of the 4+ colors, such as CMYO. The processed four colors are then mapped into three virtual colors. The mapped three virtual colors and one additional unprocessed color of the 4+ colors are then processed in a second stage using a 4-color tool. From this, a second color model of at least five colors (4+) is generated, The resulting four colors determine five printer colors, and are then mapped into three virtual colors. The mapped three virtual colors and one additional unprocessed color of the 4+ colors are then processed in a third stage using a 4-color tool, From this, a third color model of at least five colors (4+) is generated. This modeling and mapping to virtual input can be repeated for once for each color beyond 4 that is supported by the printer. The processed 4+ colors are output to a device, such as a printing engine, for rendering the image.

    Abstract translation: 4+颜色管理从4+颜色中顺次处理四种颜色,以利用四色管理工具来利用解决方案。 在用于处理4种颜色的方法和装置中,可以在第一阶段中使用四种颜色的四种颜色(诸如CMYO)来处理接收到的4种颜色的信息。 然后将经处理的四种颜色映射成三种虚拟颜色。 然后使用4色工具在第二阶段处理4种颜色的映射的三种虚拟颜色和一种其他未处理的颜色。 从此,生成至少五种颜色(4+)的第二种颜色模型。所得到的四种颜色决定了五种打印机颜色,然后被映射成三种虚拟颜色。 然后使用4色工具在第三阶段中处理4种颜色的映射的三种虚拟颜色和一种其他未处理的颜色。从此,生成至少五种颜色(4+)的第三种颜色模型。 对于由打印机支持的超过4的每种颜色,可以对虚拟输入进行此建模和映射一次。 处理的4+颜色被输出到诸如打印引擎的设备,用于渲染图像。

    Electrolytic cell diaphragm/membrane
    367.
    发明申请
    Electrolytic cell diaphragm/membrane 审中-公开
    电解细胞膜/膜

    公开(公告)号:US20100283169A1

    公开(公告)日:2010-11-11

    申请号:US12775169

    申请日:2010-05-06

    Inventor: Stuart A. Emmons

    Abstract: This invention is directed toward process and material optimization of electrolytic cell separation processes designed to generate consistent electrolytic solutions in a better salt-converting and efficient manner, as well as to increase the amount of free available chlorine generated by the electro-chemical activation of the salt. This is generally accomplished by provision of ceramic diaphragm and/or polymer membranes characterized by optimal design, construction, manufacturing, and assemblage to exacting and precise specifications with respect to chemical and material compositions, slurry formulations, ceramic mold tolerances, ceramic firing and curing conditions, dimensional measurements for thickness, dimensional measurements for gapping and placement between the anode and cathode electrodes, and machining tolerance control.

    Abstract translation: 本发明涉及电解池分离方法的工艺和材料优化,其被设计成以更好的盐转化和有效的方式产生一致的电解溶液,以及增加由电化学活化产生的游离可用氯的量 盐。 这通常通过提供陶瓷隔膜和/或聚合物膜来实现,其特征在于优化设计,结构,制造和组装,以符合关于化学和材料组成,浆料配方,陶瓷模具公差,陶瓷烧制和固化条件的精确和精确的规格 ,用于厚度的尺寸测量,用于在阳极和阴极之间的间隙和放置的尺寸测量以及加工公差控制。

    Network media access controller embedded in an integrated circuit host interface
    369.
    发明授权
    Network media access controller embedded in an integrated circuit host interface 有权
    网络媒体访问控制器嵌入在集成电路主机接口中

    公开(公告)号:US07761643B1

    公开(公告)日:2010-07-20

    申请号:US12352225

    申请日:2009-01-12

    CPC classification number: G06F15/7867

    Abstract: A media access controller system embedded in an integrated circuit is described. A platform dependent bridge for communicating with a first processor, where the platform dependent bridge is associated with a platform of the first processor and where the first processor is embedded in an integrated circuit. Host interface circuitry is coupled to the platform dependent bridge and is configured to provide a processor interface, where the processor interface is for communicating with the first processor via the platform dependent bridge and where the processor interface has a platform independent bus for communication with a second processor. At least one media access controller is coupled to the host interface circuitry.

    Abstract translation: 描述嵌入在集成电路中的媒体访问控制器系统。 用于与第一处理器进行通信的平台相关桥接器,其中所述平台相关桥接器与所述第一处理器的平台相关联,并且所述第一处理器嵌入在集成电路中。 主机接口电路耦合到与平台相关的桥接器,并且被配置为提供处理器接口,其中处理器接口用于经由平台相关桥接器与第一处理器通信,并且处理器接口具有平台独立总线,用于与第二 处理器。 至少一个媒体访问控制器耦合到主机接口电路。

    COMBINATION THERAPY FOR THE TREATMENT-OF LOWER URINARY TRACT SYMPTOMS
    370.
    发明申请
    COMBINATION THERAPY FOR THE TREATMENT-OF LOWER URINARY TRACT SYMPTOMS 审中-公开
    用于治疗下尿路症状的组合疗法

    公开(公告)号:US20100113469A1

    公开(公告)日:2010-05-06

    申请号:US12532731

    申请日:2008-03-25

    CPC classification number: A61K31/47 A61K45/06 A61K2300/00

    Abstract: This invention concerns compositions for the treatment of Lower Urinary Tract Symptoms (LUTS), and especially LUTS which results from benign prostatic hypertrophy. The compositions of the invention comprise a Beta-3 agonist described below, optionally in combination with a 5-alpha reductase inhibitor, or an NK-1 antagonist or an alpha-1 adrenergic antagonist or an anti-muscarinic agent. The invention also includes compositions comprising a beta-3 agonist and two additional active agents selected from a 5-alpha reductase inhibitor, an NK-1 antagonist, an alpha-1 adrenergic antagonist or an anti-muscarinic agent.

    Abstract translation: 本发明涉及用于治疗下尿路症状(LUTS)的组合物,特别是由良性前列腺肥大引起的LUTS。 本发明的组合物包含下述的β-3激动剂,任选地与5-α还原酶抑制剂或NK-1拮抗剂或α-1肾上腺素能拮抗剂或抗毒蕈碱剂组合。 本发明还包括包含β-3激动剂和选自5-α还原酶抑制剂,NK-1拮抗剂,α-1肾上腺素能拮抗剂或抗毒蕈碱剂的另外的活性剂的组合物。

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