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    DUAL-PHASE CEMENT PRECURSOR SYSTEMS FOR BONE REPAIR
    31.
    发明申请
    DUAL-PHASE CEMENT PRECURSOR SYSTEMS FOR BONE REPAIR 审中-公开
    用于骨修复的双相骨水泥前体系统

    公开(公告)号：WO2007047921A2

    公开(公告)日：2007-04-26

    申请号：PCT/US2006/041034

    申请日：2006-10-19

    Applicant: ADA FOUNDATION ,  CHOW, Laurence, C. ,  TAKAGI, Shozo

    Inventor： CHOW, Laurence, C. ,  TAKAGI, Shozo

    IPC: A61K33/42

    CPC classification number: A61K33/42 ,  A61K45/06 ,  A61L24/02 ,  A61L27/12 ,  A61L27/46 ,  A61L27/50 ,  A61L27/58 ,  A61K2300/00 ,  C08L89/00

    Abstract: Disclosed are dual-phase cement precursor systems and related methods and kits. The cement precursor systems are composed of a first and second discrete phases, at least one of which is aqueous. When combined, the cement precursor phases form a cement that is suitable as a bone graft material for bone repair procedures. In preferred embodiments, the materials are highly biocompatible, osteoinductive, and bioresorbable. A number of different but not mutually exclusive cement chemistries may be employed in the cement precursor systems. For instance, hydrogel-forming polymer cements, carboxyl/calcium cements, or calcium phosphate cements may be employed.

    Abstract translation: 公开了双相水泥前体体系及相关方法和试剂盒。 水泥前体体系由第一和第二不连续相组成，其中至少一个是含水的。 当组合时，水泥前体相形成适合用作骨修复程序的骨移植材料的水泥。 在优选的实施方案中，这些材料具有高生物相容性，成骨诱导性和生物可吸收性。 在水泥前体体系中可以使用许多不同但不相互排斥的水泥化学物质。 例如，可以使用水凝胶形成聚合物水泥，羧基/钙水泥或磷酸钙水泥。

    FLUORIDE-CALCIUM COMPOSITIONS, DENTAL PRODUCTS, AND METHODS FOR PROVIDING DENTAL FLUORIDE
    36.
    发明公开
    FLUORIDE-CALCIUM COMPOSITIONS, DENTAL PRODUCTS, AND METHODS FOR PROVIDING DENTAL FLUORIDE 审中-公开
    氟化钙组合物，为了提供牙科氟化物牙科产品和方法

    公开(公告)号：EP1951187A2

    公开(公告)日：2008-08-06

    申请号：EP06836523.8

    申请日：2006-10-25

    Applicant: ADA FOUNDATION

    Inventor： CHOW, Laurence, C. ,  TAKAGI, Shozo

    IPC: A61K8/30 ,  A61K8/21

    CPC classification number: A61Q11/00 ,  A61K8/19 ,  A61K8/21 ,  A61K8/24

    Abstract: Disclosed are dental compositions and methods. In accordance with one embodiment, a dental composition includes calcium, fluorine, which is generally present in the form of fluoride, and phosphate or another stabilizing anion. The composition is stable as against precipitation of calcium fluoride during transport and storage, but is unstable against the precipitation of calcium fluoride in the oral cavity of a human. In many embodiments, the amount of fluoride may be less than the amount of fluoride used in a comparable composition intended for a similar purpose. A dental method comprises applying the composition to the oral cavity of a patient, whereupon calcium fluoride precipitates from the composition.

    DUAL-PHASE CEMENT PRECURSOR SYSTEMS FOR BONE REPAIR
    40.
    发明公开
    DUAL-PHASE CEMENT PRECURSOR SYSTEMS FOR BONE REPAIR 有权
    DOUBLE相水泥PRE-SYSTEMS骨修复

    公开(公告)号：EP1945233A2

    公开(公告)日：2008-07-23

    申请号：EP06836421.5

    申请日：2006-10-19

    Applicant: ADA FOUNDATION

    Inventor： CHOW, Laurence, C. ,  TAKAGI, Shozo

    IPC: A61K33/42 ,  A61K31/19

    CPC classification number: A61K33/42 ,  A61K45/06 ,  A61L24/02 ,  A61L27/12 ,  A61L27/46 ,  A61L27/50 ,  A61L27/58 ,  A61K2300/00 ,  C08L89/00

    Abstract: Disclosed are dual-phase cement precursor systems and related methods and kits. The cement precursor systems are composed of a first and second discrete phases, at least one of which is aqueous. When combined, the cement precursor phases form a cement that is suitable as a bone graft material for bone repair procedures. In preferred embodiments, the materials are highly biocompatible, osteoinductive, and bioresorbable. A number of different but not mutually exclusive cement chemistries may be employed in the cement precursor systems. For instance, hydrogel-forming polymer cements, carboxyl/calcium cements, or calcium phosphate cements may be employed.

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