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    Vasoocclusion coil device having a core therein
    31.
    发明申请
    Vasoocclusion coil device having a core therein 审中-公开

    公开(公告)号：US20030216772A1

    公开(公告)日：2003-11-20

    申请号：US10391152

    申请日：2003-03-20

    Applicant: Board of Regents, University of Texas System

    Inventor： Andras Konya ,  Sidney Wallace ,  Kenneth Carroll Wright

    IPC: A61M029/00

    CPC classification number: A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/1215 ,  A61B2017/1205

    Abstract: A coil-type vasoocclusion device (10) for establishing an embolus or vascular occlusion in a human or veterinary patient is adapted for introduction into the patient via a catheter (32). The device (10) first includes a coil (12) having proximal and distal coil ends (16,18) and a coil lumen (20). The device (10) also includes a core (22) disposed in at least part of the coil lumen (20), the core having proximal and distal core ends (24,26). Only one core end (24 or 26) is directly affixed to a respective end (16 or 18) of the coil (12); the other core end (26 or 24) is not directly connected to either end (16 or 18) of the coil (12). The core (22) is preferably nitinol in a superelastic state, being in other than its stress induced, martensitic condition. The device (10) can include a thrombogenic material (38) connected to or carried by the coil (12). The coil (12) is preferably adapted to achieve a suitable secondary shape (60) when deployed from the catheter (32). A medical device (40) combining the catheter (32), a pusher (34), a coupling (30) and the vasoocclusion device (10) is also disclosed. The vasoocclusion device (10) is easily repositioned in the vascular system, thereby ensuring proper deployment, and also enjoys a dislodging force about twice as great as comparable coil-type devices lacking the core (22), substantially or completely preventing migration of the device (10) after its deployment.

    Computer program products, systems and methods for information discovery and relational analyses
    39.
    发明申请
    Computer program products, systems and methods for information discovery and relational analyses 审中-公开
    用于信息发现和关系分析的计算机程序产品，系统和方法

    公开(公告)号：US20040093331A1

    公开(公告)日：2004-05-13

    申请号：US10665981

    申请日：2003-09-19

    Applicant: Board of Regents, University of Texas System

    Inventor： Harold R. Garner ,  Jonathan D. Wren

    IPC: G06F007/00

    CPC classification number: G06N5/022 ,  G16B40/00 ,  G16B50/00 ,  Y02A90/26

    Abstract: The present invention is a system, method for accessing domains of information to identify heretofore unknown relationships between disparate sources of data to seek and obtain knowledge, the invention includes a source of data with one or more domains of information, an Object-Relationship Database for integrating objects from one or more domains of information and a knowledge discovery engine where relationships between two or more objects are identified, retrieved, grouped, ranked, filtered and numerically evaluated.

    Abstract translation: 本发明是一种用于访问信息领域的系统，方法，用于识别不同数据源之间的未知关系，以寻求和获取知识，本发明包括具有一个或多个信息域的数据源，一个对象关系数据库 集成来自一个或多个信息域的对象以及知识发现引擎，其中识别，检索，分组，排序，过滤和数值评估两个或多个对象之间的关系。

    UspA1 and UspA2 antigens of moraxella catarrhalis
    40.
    发明申请
    UspA1 and UspA2 antigens of moraxella catarrhalis 失效
    UspA1和UspA2卡他莫拉菌素抗原

    公开(公告)号：US20030032772A1

    公开(公告)日：2003-02-13

    申请号：US09952267

    申请日：2001-09-12

    Applicant: The Board of Regents, University of Texas System

    Inventor： Eric J. Hansen ,  Christoph Aebi ,  Leslie D. Cope ,  Isobel Maciver ,  Michael J. Fiske ,  Ross A. Fredenburg

    IPC: C07K014/435

    CPC classification number: C07K14/212 ,  A61K39/00 ,  C07K16/1217

    Abstract: The present invention discloses the existence of two novel proteins UspA1 and UspA2, and their respective genes uspA1 and uspA2. Each protein encompasses a region that is conserved between the two proteins and comprises an epitope that is recognized by the MAb 17C7. One or more than one of these species may aggregate to form the very high molecular weight form (i.e. greater than 200 kDa) of the UspA antigen. Compositions and both diagnostic and therapeutic methods for the treatment and study of M. catarrhalis are disclosed.

    Abstract translation: 本发明公开了两种新型蛋白质UspA1和UspA2及其各自的基因uspA1和uspA2的存在。 每个蛋白质包含在两种蛋白质之间保守的区域，并且包含由MAb 17C7识别的表位。 这些物质中的一种或多于一种可能聚集形成UspA抗原的非常高分子量形式（即大于200kDa）。 公开了组合物以及用于治疗和研究卡他莫拉菌的诊断和治疗方法。

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