公开(公告)号：WO2007098187A2

公开(公告)日：2007-08-30

申请号：PCT/US2007/004472

申请日：2007-02-22

Applicant: EDWARDS LIFESCIENCES CORPORATION ,  CURRY, Kenneth, M.

Inventor： CURRY, Kenneth, M.

CPC classification number: H05K3/247 ,  A61B5/1486 ,  A61B2562/125 ,  A61N1/05 ,  G01N27/3271 ,  H01L2924/0002 ,  H05K1/118 ,  H05K3/28 ,  H05K3/4664 ,  H05K2201/035 ,  H05K2201/09436 ,  H05K2203/0574 ,  Y10T29/4916 ,  H01L2924/00

Abstract: A method of creating an active electrode that may include providing a flex circuit having an electrode made of a first material and providing a first mask over the flex circuit, the first mask having an offset region and an opening that exposes the electrode. The method may also include depositing a second material over the offset region and the opening, the second material being different from the first material an providing a second mask over the second material, the second mask having a opening over a portion of the second material that is over the offset region.

Abstract translation: 一种产生有源电极的方法，其可以包括提供具有由第一材料制成的电极并在柔性电路上提供第一掩模的柔性电路，第一掩模具有偏移区域和暴露电极的开口。 该方法还可以包括在偏移区域和开口上沉积第二材料，第二材料与第一材料不同，在第二材料上提供第二掩模，第二掩模在第二材料的一部分上具有开口， 在偏移区域之上。

公开(公告)号：WO1994006019A1

公开(公告)日：1994-03-17

申请号：PCT/US1993008109

申请日：1993-08-26

Applicant: VIA MEDICAL CORPORATION ,  WONG, David, K. ,  CURRY, Kenneth, M.

Inventor： VIA MEDICAL CORPORATION

IPC: G01N33/96

CPC classification number: A61B5/1486 ,  A61B5/14532 ,  A61B5/1495 ,  G01N33/4925 ,  G01N33/84 ,  G01N33/96 ,  G01N2496/70 ,  G01N2496/80

Abstract: Novel calibration solutions are provided which are useful, for example, with sensor assemblies used for analysis of CO2, and optionally, for concurrent analysis of O2, especially in combination infusion fluid delivery/blood chemistry analysis systems which include a sensor assembly with each of the assembly electrodes mounted in an electrode cavity in the assembly. The analysis system used in the practice of the present invention typically includes provision for delivering infusion fluid and measuring blood chemistry during reinfusion of the physiological fluid at approximately the same flow rates. The invention calibration solutions are useful for calibrating an array of sensors capable of simultaneously measuring a number of blood chemistry parameters, including the partial pressures (tensions) of carbon dioxide and oxygen, pH (hydrogen ion), sodium, potassium, ionized calcium, ionized magnesium, chloride, glucose, lactate and hematocrit, in body fluids. More particularly, this invention relates to the use of an infusible intravenous solution to facilitate calibration on a regular basis for every individual sensor in a sensor assembly, which is in constant fluid communication with the body regardless of whether the sensors are (ex vivo) or (in vivo).

Abstract translation: 提供了新的校准解决方案，例如，用于分析二氧化碳的传感器组件，以及可选地用于O2的并发分析，特别是在组合输液输送/血液化学分析系统中，包括传感器组件 组装电极安装在组件中的电极腔中。 在本发明的实践中使用的分析系统通常包括在大致相同的流速下在生理流体的再灌注期间输​​送输液和测量血液化学物质。 本发明的校准解决方案可用于校准能够同时测量多个血液化学参数的传感器阵列，包括二氧化碳和氧气的分压（张力），pH（氢离子），钠，钾，离子化钙，离子化 镁，氯化物，葡萄糖，乳酸盐和血细胞比容。 更具体地说，本发明涉及无限静脉注射溶液的使用以有助于定期地对传感器组件中的每个单独的传感器进行校准，传感器组件与身体不断流体连通，而不管传感器是否是离体的 （体内）。

公开(公告)号：WO2010093945A3

公开(公告)日：2010-12-16

申请号：PCT/US2010024128

申请日：2010-02-12

Applicant: GLAUKOS CORP ,  HAFFNER DAVID ,  CURRY KENNETH

Inventor： HAFFNER DAVID ,  CURRY KENNETH

IPC: A61F9/00 ,  A61M37/00

CPC classification number: A61F9/00781 ,  A61F9/0017 ,  A61K31/00 ,  A61L27/18 ,  A61L27/54 ,  A61L2300/604 ,  A61L2430/16 ,  A61M25/00 ,  A61M25/0105 ,  A61M27/00 ,  A61M37/00 ,  A61M2025/0286 ,  A61M2210/0612 ,  C08L67/04

Abstract: Devices and methods for treating intraocular pressure are disclosed. The devices include drug delivery implants for treating ocular tissue. Optionally, the devices also include shunts for draining aqueous humor from the anterior chamber to the uveoscleral outflow pathway, including the supraciliary space and the suprachoroidal space. The drug delivery implants can be implanted in ab interno or ab externo procedures.

Abstract translation: 公开了用于治疗眼内压的装置和方法。 这些装置包括用于治疗眼组织的药物递送植入物。 任选地，所述装置还包括用于将房水从前房引流到包括睫状体上空间和脉络膜上腔的葡萄膜巩膜外流路的分流器。 药物输送植入物可以植入内部或外部程序。

公开(公告)号：WO2010115146A2

公开(公告)日：2010-10-07

申请号：PCT/US2010/029840

申请日：2010-04-02

Applicant: JONES, Mark, L. ,  CURRY, Kenneth, M.

Inventor： JONES, Mark, L. ,  CURRY, Kenneth, M.

IPC: E21B10/54 ,  E21B10/62 ,  E21B10/18

CPC classification number: E21B10/55

Abstract: Embodiments of the present invention include a drill bit configured for boring holes or wells into the earth. Embodiments include a drill bit comprised of a plurality of blades. A first plurality of the blades has cutting elements positioned substantially within the cone section of the drill bit. A second plurality of blades has cutting elements positioned substantially within the blade flank section and the blade shoulder section. Another embodiment of the first plurality of blades in which the blades end or truncate at a radial distance substantially less than the radial distance of the blade shoulder section from the center of the drill bit.

Abstract translation: 本发明的实施例包括一种钻孔，其被配置用于将孔或孔钻入地球。 实施例包括由多个叶片组成的钻头。 第一多个叶片具有基本上位于钻头的锥形部分内的切割元件。 第二多个叶片具有基本上位于叶片侧面部分和叶片肩部内的切割元件。 第一多个叶片的另一实施例，其中叶片以基本上小于叶片肩部与钻头中心的径向距离的径向距离端接或截截。

公开(公告)号：WO2010068587A3

公开(公告)日：2010-09-16

申请号：PCT/US2009066968

申请日：2009-12-07

Applicant: EDWARDS LIFESCIENCES CORP ,  CURRY KENNETH ,  FJIELD TODD ,  HIGGINS MICHAEL J ,  CARLIN PATRICK ,  CARLIN GREGORY J

Inventor： CURRY KENNETH ,  FJIELD TODD ,  HIGGINS MICHAEL J ,  CARLIN PATRICK ,  CARLIN GREGORY J

IPC: A61B5/145 ,  A61B5/1459

CPC classification number: A61B5/14532 ,  A61B5/14865 ,  A61B2562/242 ,  B65D81/05 ,  B65D81/2061 ,  B65D81/2084

Abstract: There are provided methods of packaging and packages that prevent damage of the package contents while maintaining sterility and that limit the negative effects of sterilization on sensors such as enzyme sensors. A method of packaging an enzyme sensor includes providing an enzyme sensor such as a glucose oxidase sensor in a gas impermeable package comprising one or more of oxygen and water, removing a significant portion of the oxygen and water present in the package, and sealing the package. The resulting package comprises the enzyme sensor in an atmosphere that is substantially free of oxygen and water. The package can also include a pressure indicator that indicates when the package has exceeded a predetermined pressure.

Abstract translation: 提供了包装和包装方法，以防止包装内容物受损，同时保持无菌状态，并限制灭菌对诸如酶传感器等传感器的负面影响。 包装酶传感器的方法包括在不透气包装中提供酶传感器如葡萄糖氧化酶传感器，所述不透气包装包含氧气和水中的一种或多种，​​除去包装中存在的大部分氧气和水，并将包装 。 所得到的包装包含在基本上不含氧气和水的气氛中的酶传感器。 包装还可以包括指示包装何时超过预定压力的压力指示器。

公开(公告)号：WO2010099512A1

公开(公告)日：2010-09-02

申请号：PCT/US2010/025703

申请日：2010-02-27

Applicant: JONES, Mark, L. ,  CURRY, Kenneth, M. ,  ROSS, Jeffery, T.

Inventor： JONES, Mark, L. ,  CURRY, Kenneth, M. ,  ROSS, Jeffery, T.

IPC: E21B10/46 ,  E21B10/567

CPC classification number: E21B10/55 ,  E21B10/602 ,  E21B10/633

Abstract: Embodiments of the present invention include a drill bit configured for boring holes or wells into the earth. Embodiments include a drill bit comprised of a plurality of blades. Each of the plurality of blades includes one or more holes therethrough configured to receive a cutter that is secured therein. The cutters are secured in the hole with securing means that typically prevent the cutters from being removed when the drill bit is in use but allow the cutters to be removed from the holes when the drill bit is not in use.

Abstract translation: 本发明的实施例包括一种钻孔，其被配置用于将孔或孔钻入地球。 实施例包括由多个叶片组成的钻头。 多个叶片中的每一个包括一个或多个通孔，其构造成接收固定在其中的切割器。 切割器通过固定装置固定在孔中，该固定装置通常防止当钻头使用时切割器被移除，但是当钻头不使用时允许切割器从孔中移除。

公开(公告)号：WO2008076574A3

公开(公告)日：2008-06-26

申请号：PCT/US2007/084993

申请日：2007-11-16

Applicant: EDWARDS LIFESCIENCES CORPORATION ,  FJIELD, Todd ,  HIGGINS, Michael, J. ,  CURRY, Kenneth ,  CARLIN, Patrick

Inventor： FJIELD, Todd ,  HIGGINS, Michael, J. ,  CURRY, Kenneth ,  CARLIN, Patrick

IPC: A61B5/1486

Abstract: A temperature compensation method for an enzyme electrode by measuring an operating temperature of the enzyme electrode, measuring the current generated by the enzyme electrode, determining a deviation in measurement between the current generated and a reference current at the operating temperature, determining an enzyme concentration corresponding to the measured current, and calibrating the enzyme concentration to compensate for the deviation in measurement.

公开(公告)号：WO0102340B1

公开(公告)日：2001-11-08

申请号：PCT/CA0000757

申请日：2000-06-30

Applicant: IGT PHARMA INC ,  CURRY KENNETH

Inventor： CURRY KENNETH

IPC: C07C229/36 ,  C07C229/46 ,  C07C229/50 ,  C07C255/42 ,  C07C255/47 ,  C07D233/76 ,  C07D235/02 ,  A61K31/195 ,  A61K31/275 ,  A61K31/4166 ,  C07C227/00 ,  C07C255/26 ,  C07D233/40

CPC classification number: C07D235/02 ,  C07C229/36 ,  C07C229/46 ,  C07C229/50 ,  C07C255/42 ,  C07C255/47 ,  C07C2602/08 ,  C07D233/76

Abstract: The present invention relates to therapeutically active novel aminoindanes of formula (I). Also provided is a method of preparing compounds of formula (I), and pharmaceutical compositions comprising the compounds. The novel compounds act as modulators of metabotropic glutamate receptors and, as such, are useful in treating diseases of the central nervous system related to the metabotropic glutamate receptor system.

Abstract translation: 本发明涉及式（I）的治疗活性新型氨基茚满。 还提供了制备式（I）化合物的方法和包含该化合物的药物组合物。 这些新化合物充当代谢型谷氨酸受体调节剂，因此可用于治疗与代谢型谷氨酸受体系统有关的中枢神经系统疾病。

公开(公告)号：WO9954280B1

公开(公告)日：1999-12-16

申请号：PCT/CA9900311

申请日：1999-04-19

Applicant: CURRY KENNETH ,  PAJOUHESH HASSAN

Inventor： CURRY KENNETH ,  PAJOUHESH HASSAN

IPC: C07D233/76 ,  A61K31/198 ,  A61K31/382 ,  A61P1/08 ,  A61P9/02 ,  A61P9/10 ,  A61P21/02 ,  A61P25/00 ,  A61P25/04 ,  A61P25/06 ,  A61P25/14 ,  A61P25/16 ,  A61P25/18 ,  A61P25/20 ,  A61P25/22 ,  A61P25/28 ,  A61P25/30 ,  A61P27/02 ,  C07C69/00 ,  C07C227/12 ,  C07C227/24 ,  C07C229/28 ,  C07C229/46 ,  C07C255/28 ,  C07C309/27 ,  C07D233/78 ,  C07D233/86 ,  C07D335/12 ,  C07D335/20 ,  C07F9/38 ,  A61K31/195 ,  C07F5/02

CPC classification number: C07F9/383 ,  C07C69/753 ,  C07C229/28 ,  C07C255/28 ,  C07C2603/00 ,  C07C2603/86 ,  C07C2603/90 ,  C07D233/86

Abstract: The present invention relates to therapeutically active cubane compounds, a method of preparing the same, and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases of the central nervous system related to the metabotropic glutamate receptor system.

Abstract translation: 本发明涉及治疗活性的立方烷化合物，其制备方法以及包含该化合物的药物组合物。 该新型化合物可用于治疗与代谢型谷氨酸受体系统相关的中枢神经系统疾病。

公开(公告)号：WO2012148965A2

公开(公告)日：2012-11-01

申请号：PCT/US2012/034908

申请日：2012-04-25

Applicant: NEWTECH DRILLING PRODUCTS, LLC ,  JONES, Mark, L. ,  CURRY, Kenneth, M.

Inventor： JONES, Mark, L. ,  CURRY, Kenneth, M.

IPC: E21B10/43 ,  E21B10/56 ,  E21B10/62

CPC classification number: E21B10/43 ,  E21B10/5673 ,  E21B10/633

Abstract: A drill bit for drilling a hole through earth and hard materials, the drill bit including a bit body having an inner bore and a cutting head at a cutting end, the cutting head including a center portion with one or more apertures extending from the cutting end to the inner bore, a perimeter portion projecting radially outward to form a plurality of blades divided by a plurality of junk slots, a cutting face, and a plurality of cutter receptacles spaced about the cutting face. A plurality of cutters with cutter tips terminating in points are in mounted into the cutter receptacles at a pitch angle relative to the cutting face, and with the plurality of cutter points together defining a projected cutting surface.

Abstract translation: 一种用于通过地面和硬质材料钻孔的钻头，所述钻头包括具有内孔的钻头体和在切割端处的切割头，所述切割头包括具有从所述切割端延伸的一个或多个孔的中心部分 所述内孔具有径向向外突出的周边部分，以形成由多个垃圾槽分割的多个叶片，切割面以及围绕切割面间隔开的多个切割器容器。 多个切割器刀具终止于点，以相对于切割面的倾斜角度安装到切割器容器中，并且多个切割点一起限定突出的切割表面。