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    NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF
    2.
    发明授权
    NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF 有权
    NOVEL SPIRO [2.4]庚烷氨基羧酸化合物及其衍生物

    公开(公告)号：EP1280760B1

    公开(公告)日：2004-04-28

    申请号：EP01929156.6

    申请日：2001-05-11

    Applicant: Curry, Kenneth

    Inventor： Curry, Kenneth

    IPC: C07C229/50 ,  A61K31/196 ,  A61P25/00 ,  C07C229/46

    CPC classification number: C07C229/50 ,  C07C229/46 ,  C07C2603/94

    Abstract: The present invention relates to therapeutically active novel spiro[2.4]heptane amino carboxy compounds and derivatives thereof. Also provided is a method of preparing compounds of Formula (I), and pharmaceutical compositions comprising the compounds. The novel compounds act as modulators of metabotropic glutamate receptors and, as such, are useful in treating diseases of the central nervous system related to the metabotropic glutamate receptor system.

    Abstract translation: 本发明涉及具有治疗活性的新型螺[2.4]庚烷氨基羧基化合物及其衍生物。 还提供了制备式（I）化合物的方法和包含所述化合物的药物组合物。 这些新化合物充当代谢型谷氨酸受体调节剂，因此可用于治疗与代谢型谷氨酸受体系统有关的中枢神经系统疾病。

    Reverse circulation bit assembly
    6.
    发明专利
    Reverse circulation bit assembly 未知

    公开(公告)号：AU2012326204A1

    公开(公告)日：2014-05-08

    申请号：AU2012326204

    申请日：2012-10-17

    Applicant: ATLAS COPCO SECOROC LLC ,  JONES MARK ,  JOHNSON KYLE ,  ROSS JEFFERY ,  CURRY KENNETH

    Inventor： JONES MARK L ,  CURRY KENNETH M ,  ROSS JEFFERY T ,  JOHNSON KYLE E

    IPC: E21B10/32 ,  E21B10/62

    Abstract: A drill bit assembly for boring including a drill bit and a bit sub. A front bit end has a plurality cutting elements at a forward face of the front bit end and a first fluid return passage extending through the drill bit to a rear bit end. The bit sub couples to the rear bit end. The bit sub includes a bore disposed at a front sub end sized and shaped to receive the rear bit end of the drill bit. A plurality of legs extends from a mid-sub region toward the front sub end between pairs of cutting elements. The plurality of legs has a fluid delivery passage disposed therein with the fluid delivery passage extending from the plurality of legs to a rear sub bit end. The bit sub has a second fluid return passage connecting the first fluid return passage to the rear sub bit end.

    NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF
    10.
    发明专利
    NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF 未知

    公开(公告)号：CA2407777A1

    公开(公告)日：2001-11-15

    申请号：CA2407777

    申请日：2001-05-11

    Applicant: CURRY KENNETH

    Inventor： CURRY KENNETH

    IPC: C07C229/46 ,  C07C229/50 ,  A61K31/196 ,  A61P25/00

    Abstract: The present invention relates to therapeutically active novel spiro[2.4]heptane amino carboxy compounds and derivatives thereof. Also provided is a method of preparing compounds of Formula (I), and pharmaceutic al compositions comprising the compounds. The novel compounds act as modulators of metabotropic glutamate receptors and, as such, are useful in treating diseases of the central nervous system related to the metabotropic glutamate receptor system.

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