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公开(公告)号:DE69415849T2
公开(公告)日:1999-08-12
申请号:DE69415849
申请日:1994-04-18
Applicant: DADE CHEMISTRY SYSTEMS INC
Inventor: FERMANI NICHOLAS ROCCO , FLETCHER MARK GEORGE
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公开(公告)号:DE69228817D1
公开(公告)日:1999-05-06
申请号:DE69228817
申请日:1992-07-23
Applicant: DADE CHEMISTRY SYSTEMS INC
Inventor: ALLARD WILLIAM , OBZANSKY DAVID , VAIDYA HEMANT
IPC: C12Q1/00 , C12Q1/34 , C12Q1/42 , G01N33/535 , G01N33/543 , G01N33/74 , G01N33/58 , G01N33/546
Abstract: An assay for photometrically detecting and/or quantitating the presence of an analyte in a sample in which the signal generated by a label associated with the analyte is photometrically detected in the presence of a suspended solid support.
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公开(公告)号:AT162307T
公开(公告)日:1998-01-15
申请号:AT93110588
申请日:1993-07-02
Applicant: DADE CHEMISTRY SYSTEMS INC
Inventor: PACE SALVATORE J , HAMERSLAG JAMES DAVID
IPC: G01N27/28 , G01N27/27 , G01N27/403 , G01N27/416
Abstract: A readily disposable ion selective electrode assembly, free of onboard reagents, for use in analyzers has a reference element and plural sensor elements linearly positioned in parallel on a substrate. An elastomeric flow channel member containing two parallel grooves creates flow channels on the substrate above the elements. The substrate holds the elastomer in compression and is retained by snaps injection molded into a housing. Electrical contacts and leakfree fluidic connections are provided by spring loaded connectors through the housing. Reference and sample fluids are drawn through the respective flow channels and come together to form a liquid junction downstream from the sensor elements. Bubbles, that might otherwise cause erroneous results, are detected.
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公开(公告)号:AU6259296A
公开(公告)日:1996-12-30
申请号:AU6259296
申请日:1996-06-07
Applicant: DADE CHEMISTRY SYSTEMS INC
Inventor: WANG CHENGRONG
IPC: G01N33/53 , A61K39/00 , C07D223/22 , C07D223/26 , C07D223/32 , G01N33/532 , G01N33/94 , G01N33/546
Abstract: The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having the general formula The present invention also provides a novel carbamazepine acid compound suitable for attachment to proteins for the production of carbamazepine immunogens. The carbamazepine antigen of the present invention has the following general structure: where X is C=O, CH2 or SO2; Y is C=O, CH2, SO2; R is an alkyl and P is a protein or a hapten.
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公开(公告)号:DE69228817T2
公开(公告)日:1999-09-23
申请号:DE69228817
申请日:1992-07-23
Applicant: DADE CHEMISTRY SYSTEMS INC
Inventor: ALLARD WILLIAM , OBZANSKY DAVID , VAIDYA HEMANT
IPC: C12Q1/00 , C12Q1/34 , C12Q1/42 , G01N33/535 , G01N33/543 , G01N33/74 , G01N33/58 , G01N33/546
Abstract: An assay for photometrically detecting and/or quantitating the presence of an analyte in a sample in which the signal generated by a label associated with the analyte is photometrically detected in the presence of a suspended solid support.
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公开(公告)号:DE69415849D1
公开(公告)日:1999-02-25
申请号:DE69415849
申请日:1994-04-18
Applicant: DADE CHEMISTRY SYSTEMS INC
Inventor: FERMANI NICHOLAS ROCCO , FLETCHER MARK GEORGE
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公开(公告)号:DE69415644D1
公开(公告)日:1999-02-11
申请号:DE69415644
申请日:1994-10-27
Applicant: DADE CHEMISTRY SYSTEMS INC
Inventor: SLACK LYLE H , SNYDER LARRY E
IPC: G01N27/414 , G01N27/333
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公开(公告)号:DE69126410T2
公开(公告)日:1997-10-09
申请号:DE69126410
申请日:1991-12-11
Applicant: DADE CHEMISTRY SYSTEMS INC
Inventor: WANG CHI-CHI , SALYERS MARSHALL L , MCKEEVER ROBERT THOMAS
Abstract: An automatic chemistry system having a wheel for mounting reaction vessels is provided with a programmable permanent magnet which is selectively positioned adjacent a reaction vessel to separate magnetizable particles in the vessel from the vessels liquid contents. This facilitates performing heterogeneous immunoassays.
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公开(公告)号:DE68927428T2
公开(公告)日:1997-03-06
申请号:DE68927428
申请日:1989-08-30
Applicant: DADE CHEMISTRY SYSTEMS INC
Inventor: HUBNER ROMEO JOSE
IPC: G01N27/447 , C12M1/34 , C12Q1/68 , C12Q1/683 , C12Q3/00 , G06F17/30 , G06F19/28 , G06Q50/00 , G06T1/00 , H04N7/18 , G01N27/26 , G06K9/62
Abstract: A method is described for establishing a hierarchial library of spectra representing the point-by-point characteristics of known samples. Vectors representing each spectrum are classified according to their similarity and dissimilarity. Vectors representing unknown samples are compared to known groups of vectors according to similarity until a near match is found.
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公开(公告)号:DE69212998T2
公开(公告)日:1997-01-16
申请号:DE69212998
申请日:1992-03-13
Applicant: DADE CHEMISTRY SYSTEMS INC
Inventor: BUSSIAN RONALD WAYNE , RUGLASS JOHN ARTHUR
IPC: C12Q1/32
Abstract: The invention is drawn to a diagnostic assay for lactate dehydrogenase isoenzyme LD1 in a sample containing lactate dehydrogenase isoenzymes LD1-LD5. The disclosed assay involves the following steps: (A) adding a high molecular weight polyol, preferably polyethylene glycol having a molecular weight of 8000, to the sample to stabilize isoenzyme LD1 but not isoenzymes LD2-LD5; (B) adding an ionic amphiphile to the sample to selectively inactivate isoenzymes LD2-LD5; (C) adding sodium lactate and NAD to the sample; (D) determining LD1 by measuring a change in absorbance of the sample at 340 mm.
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