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公开(公告)号：WO2005016298A2
公开(公告)日：2005-02-24
申请号：PCT/US2004/026421
申请日：2004-08-13
Applicant: COLGATE-PALMOLIVE COMPANY , IBRAHIM, Sayed , CHOPRA, Suman, K. , PRENCIPE, Michael
Inventor： IBRAHIM, Sayed , CHOPRA, Suman, K. , PRENCIPE, Michael
IPC: A61K7/16
CPC classification number: A61Q11/00 , A61K8/0208 , A61K8/24 , A61K8/8176 , A61K8/891 , A61K2800/412 , A61K2800/43
Abstract: A composition for the rapid, temporary whitening of teeth comprising an adhesive material and whitening particulates.
Abstract translation: 用于牙齿快速临时增白的组合物，其包含粘合剂材料和增白颗粒。
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公开(公告)号：WO1996018377A1
公开(公告)日：1996-06-20
申请号：PCT/US1995016134
申请日：1995-12-13
Applicant: COLGATE-PALMOLIVE COMPANY , DIXIT, Nagaraj , DURGA, Gary , BURKE, Michael, R. , PRENCIPE, Michael , PATEL, Suryakant
Inventor： COLGATE-PALMOLIVE COMPANY
IPC: A61K07/16
CPC classification number: A61K33/24
Abstract: A method for the preparation of an aqueous stable premix containing a stannous ion releasing compound useful in the manufacture of an aqueous oral care composition containing a stable stannous ion releasing compound which comprises first dissolving the stannous compound in an aqueous solution of citric acid or its alkali metal salt to prepare the aqueous premix and then adding the premix to the vehicle of the oral care composition.
Abstract translation: 一种制备含有稳定的亚锡离子释放化合物的水性稳定预混物的方法，该化合物可用于制备含有稳定的亚锡离子释放化合物的水性口腔护理组合物，其包括首先将亚锡化合物溶解在柠檬酸或其碱的水溶液 金属盐，以制备含水预混物，然后将预混物加入到口腔护理组合物的载体中。
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公开(公告)号：WO2014203263A1
公开(公告)日：2014-12-24
申请号：PCT/IN2013/000376
申请日：2013-06-18
Applicant: COLGATE-PALMOLIVE COMPANY , PRENCIPE, Michael , POTNIS, Shashank , FISHER, Steven , LEWIS, Navin , TAMBS, Gary
Inventor： PRENCIPE, Michael , POTNIS, Shashank , FISHER, Steven , LEWIS, Navin , TAMBS, Gary
Abstract: The invention provides antibacterial combinations of essential oils comprising bisabolol and one or more essential oils selected from citral, carvacrol, oregano extract, and rosemary, or comprising carvacrol and one or more essential oils selected from bisabolol, thymol, and rosemary, together with compositions, e.g., oral care compositions, comprising these combinations, and uses therefore.
Abstract translation: 本发明提供了包含红没药醇和选自柠檬醛，香芹酚，牛至提取物和迷迭香的一种或多种精油或包含选自红没药醇，百里酚和迷迭香的一种或多种精油的精油的抗菌组合，以及组合物， 例如，包含这些组合的口腔护理组合物，因此。
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公开(公告)号：WO2014100930A1
公开(公告)日：2014-07-03
申请号：PCT/CN2012/087272
申请日：2012-12-24
Applicant: COLGATE-PALMOLIVE COMPANY , PRENCIPE, Michael , HUANG, Xiaoyi , XIE, Yuanhui
Inventor： PRENCIPE, Michael , HUANG, Xiaoyi , XIE, Yuanhui
CPC classification number: A61K8/24 , A61K8/19 , A61K8/21 , A61K8/27 , A61K8/365 , A61K2800/30 , A61Q11/00
Abstract: The present invention relates to an oral care composition with a high water content which has improved robustness towards microbial challenge. The oral care composition includes compositions comprising from 0.125 wt% to 0.75 wt% of a water soluble source of stannous ions, wherein the composition comprises at least 50 wt% water and wherein the source of stannous ions is selected from the group consisting of stannous chloride, stannous pyrophosphate, stannous formate, stannous acetate, stannous gluconate, stannous lactate, stannous tartrate, stannous oxalate, stannous malonate, stannous citrate, stannous ethylene glyoxide, and mixtures thereof.
Abstract translation: 本发明涉及具有高水含量的口腔护理组合物，其具有改善的对微生物攻击的鲁棒性。 口腔护理组合物包括包含0.125重量％至0.75重量％的水溶性亚锡离子源的组合物，其中所述组合物包含至少50重量％的水，并且其中所述亚锡离子源选自氯化亚锡 ，焦磷酸亚锡，甲酸亚锡，乙酸亚锡，葡萄糖酸亚锡，乳酸亚锡，酒石酸亚锡，草酸亚锡，丙二酸亚锡，柠檬酸亚锡，亚乙基亚乙基氧化物及其混合物。
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公开(公告)号：WO2013089761A1
公开(公告)日：2013-06-20
申请号：PCT/US2011/065310
申请日：2011-12-16
Applicant: COLGATE-PALMOLIVE COMPANY , SZEWCZYK, Gregory , PATEL, Neeta Atul , JOGUN, Suzanne , PRENCIPE, Michael
Inventor： SZEWCZYK, Gregory , PATEL, Neeta Atul , JOGUN, Suzanne , PRENCIPE, Michael
CPC classification number: A61K8/731 , A61K8/0216 , A61K8/345 , A61K8/347 , A61K8/463 , A61K8/4973 , A61K8/8164 , A61K2800/43 , A61K2800/5424 , A61Q11/00 , A61Q17/005
Abstract: Described herein are oral care compositions comprising an antibacterial agent and a dissolvable film comprising a pigment which provide a color change signal after a sufficient period of brushing, wherein the dentifrice base has water activity less than 0.78 and comprises anionic polymer in free or salt form 10-25% by weight of the dentifrice base, and anionic surfactant less than 3% by weight; together with methods of making and using the compositions.
Abstract translation: 本文描述了包含抗菌剂和可溶性膜的口腔护理组合物，其包含在充分的刷牙时间后提供变色信号的颜料，其中洁齿剂碱的水分活度小于0.78，并且包含游离或盐形式的阴离子聚合物10 -25重量％的洁牙剂碱，阴离子表面活性剂小于3重量％; 以及制备和使用组合物的方法。
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Patent Agency Ranking
公开(公告)号：WO2012166142A1
公开(公告)日：2012-12-06
申请号：PCT/US2011/038867
申请日：2011-06-02
Applicant: COLGATE-PALMOLIVE COMPANY , FISHER, Steven , ZAIDEL, Lynette , PRENCIPE, Michael
Inventor： FISHER, Steven , ZAIDEL, Lynette , PRENCIPE, Michael
CPC classification number: A61K8/8176 , A61K8/19 , A61K8/21 , A61K8/24 , A61K8/27 , A61K8/365 , A61K2800/48 , A61Q11/00
Abstract: A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients. The composition comprises a source of metal ions, an inorganic phosphate salt having four or more phosphorus atoms and a cross -linked polyvinylpyrrolidone thickening agent in a single phase. Preferred metal ions are stannous, copper and zinc, in particular from zinc citrate and stannous fluoride.
Abstract translation: 具有低水相的洁齿剂组合物，其含有有效量的多磷酸盐和离子活性成分。 该组合物包含金属离子源，具有四个或更多个磷原子的无机磷酸盐和单相中的交联聚乙烯吡咯烷酮增稠剂。 优选的金属离子是亚锡，铜和锌，特别是柠檬酸锌和氟化亚锡。
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公开(公告)号：WO2012087288A2
公开(公告)日：2012-06-28
申请号：PCT/US2010/061414
申请日：2010-12-21
Applicant: COLGATE-PALMOLIVE COMPANY , PORTER, Venda , PATEL, Vyoma , FISHER, Steven Wade , MORGAN, Andre Michelle , PRENCIPE, Michael , JARACZ, Stanislav
Inventor： PORTER, Venda , PATEL, Vyoma , FISHER, Steven Wade , MORGAN, Andre Michelle , PRENCIPE, Michael , JARACZ, Stanislav
IPC: H05B41/16
CPC classification number: A61K8/58 , A61K8/24 , A61K8/27 , A61K8/36 , A61K8/361 , A61K8/362 , A61K8/365 , A61K8/44 , A61Q11/00
Abstract: Described herein are compositions comprising combinations of metal salts, and methods of preparing and using the same.
Abstract translation: 本文描述了包含金属盐组合的组合物，以及制备和使用它们的方法。
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公开(公告)号：WO2010141694A2
公开(公告)日：2010-12-09
申请号：PCT/US2010/037223
申请日：2010-06-03
Applicant: COLGATE-PALMOLIVE COMPANY , PORTER, Venda , MORGAN, Andre , JARACZ, Stanislav , GRONLUND, Jennifer , XU, Guofeng , WU, Donghui , PRENCIPE, Michael , SUBRAMANYAM, Ravi
Inventor： PORTER, Venda , MORGAN, Andre , JARACZ, Stanislav , GRONLUND, Jennifer , XU, Guofeng , WU, Donghui , PRENCIPE, Michael , SUBRAMANYAM, Ravi
IPC: A61Q11/00
CPC classification number: A61Q11/00 , A61K8/58 , A61K31/69 , A61Q17/005 , Y10S514/835
Abstract: A stabilized topical composition comprising a borinic acid derivative, e.g., a borinic ester.
Abstract translation: 包含硼酸衍生物例如硼酸酯的稳定的局部组合物。
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公开(公告)号：WO2010141693A2
公开(公告)日：2010-12-09
申请号：PCT/US2010/037220
申请日：2010-06-03
Applicant: COLGATE-PALMOLIVE COMPANY , PORTER, Venda , MORGAN, Andre , JARACZ, Stanislav , GRONLUND, Jennifer , XU, Guofeng , WU, Donghui , PRENCIPE, Michael , SUBRAMANYAM, Ravi
Inventor： PORTER, Venda , MORGAN, Andre , JARACZ, Stanislav , GRONLUND, Jennifer , XU, Guofeng , WU, Donghui , PRENCIPE, Michael , SUBRAMANYAM, Ravi
IPC: A61Q11/00
CPC classification number: A61Q11/00 , A61K8/58 , A61K31/69 , A61Q17/005 , Y10S514/835
Abstract: A stabilized oral care composition comprising a borinic acid derivative, e.g., a borinic ester.
Abstract translation: 一种稳定的口腔护理组合物，其包含硼酸衍生物，例如硼酸酯。
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40.发明申请
公开(公告)号：WO2010115039A3
公开(公告)日：2010-10-07
申请号：PCT/US2010/029684
申请日：2010-04-01
Applicant: COLGATE-PALMOLIVE COMPANY , CHOPRA, Suman, K. , PRENCIPE, Michael , ZAIDEL, Lynette
Inventor： CHOPRA, Suman, K. , PRENCIPE, Michael , ZAIDEL, Lynette
Abstract: The invention encompasses combinations of bioactive glass composition and potassium salts that are useful in conjunction with delivery agent such as, for example, toothpastes, mouthwashes, and oral gels. In certain embodiments, the compositions of the invention form a rapid and continuous reaction with body fluids (e.g., saliva) to promote the immediate and long- term release of Ca and P ions to produce a stable crystalline layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.
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