Abstract:
A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.
Abstract:
Vaso-occlusive devices (50(1)) for occlusion of a body cavity are provided. The vaso-occlusive devices (50(1)) include an elongate vaso-occlusive member (12) having one or more key-ways (54a, 54b) and one or more fold lines (15c). Methods of using the vaso-occlusive devices are also described.
Abstract:
Compositions comprising injection-molded vaso-occlusive elements (40). A method of producing the vaso-occlusive elements comprises the step of injection molding a polymeric material into a three-dimensional configuration. The injection molded elements include severable junctions (50) detachably connected to a pusher element.
Abstract:
A delivery wire assembly for delivery of an occlusive device to a location in a patient's vasculature includes a delivery wire conduit having a proximal tubular portion connected to a distal coil portion, and a conduit lumen extending through the proximal tubular portion and the distal coil portion. The delivery wire assembly also includes a core wire disposed in the conduit lumen and having a distal end coupled to an occlusive device. The distal coil portion of the delivery wire assembly includes a plurality of zones and the plurality of zones decrease in stiffness distally along the length of the distal coil portion of the delivery wire assembly.
Abstract:
A delivery wire assembly has a proximal tubular portion, a distal coil portion, and a lumen extending at least partially through the assembly, the delivery wire forming a first conductive path extends through the lumen from a proximal end of the delivery wire assembly to a location distal with respect to the distal coil portion. The distal extension includes a sacrificial detachment zone. The delivery wire assembly further includes a second conductive path formed by the proximal tubular portion and distal coil portion. A delivery wire adapter has a distal end comprising a plurality of fingers configured to interface between adjacent open pitched windings of the proximal end of an attached occlusive coil. The proximal end of the delivery wire adapter is secured to a distal portion of the delivery wire.
Abstract:
A multimode occlusion and stenosis treatment apparatus comprises an elongated member having a distal region, and an enclosure secured to the distal region of the elongated member, the enclosure comprising a flow restoring segment, an open segment distal of the flow restoring segment, and a capture segment distal the open segment. In use, a catheter is inserted into a selected blood vessel until a distal end of the catheter is distal of an occlusive or stenotic lesion in the blood vessel. The multimode occlusion and stenosis treatment apparatus is inserted into the catheter, the flow restoring segment is aligned with the lesion, and the catheter is withdrawn relative to the apparatus until a distal end of the catheter is proximal of the flow restoring segment to thereby allow the flow restoring segment to expand radially and compress the lesion against an inner surface of the blood vessel.
Abstract:
Compositions comprising devices (10) for retrieving objects from a subject, for example the subject's vasculature, are described. Also described are methods of making and using these devices.
Abstract:
This is a device for occluding a space within the body. In particular, the device comprises an elastomeric porous material, preferably having a pore size of greater than about 30 microns. The elastomeric porous material is optionally expandable from its uncompressed form. The devices may be placed in a desired site within a mammal and are useful in inhibiting the formation of scar tissue.