Abstract:
본발명은콜라겐가수분해물을유효성분으로포함하여필러의효능을장기간유지시키는비경구조성물에관한것이다. 본발명에의한조성물은히알루론산필러효능을보다장시간유지시킬수 있으므로, 보다적은횟수로필러를시술하여도그 효과가유지될수 있어서피부자극역시줄어든다는장점이있다. 아울러비경구투여로투여방법이간단하고피부에직접적으로침투할수 있어서, 즉각적인효과가가능하다는장점이있다.
Abstract:
PURPOSE: A composition containing a Camellia sinensis leaf extract, a Camellia sinensis flower extract, and a Camellia sinensis seed extract as active ingredients is provided to activate AMP-activated protein kinase (AMPK), to suppress fatty acid synthesis, and to promote fatty acid oxidation and glucose absorption, thereby preventing and treating metabolic syndrome. CONSTITUTION: A composition for preventing or treating metabolic syndrome contains a Camellia sinensis leaf extract, a Camellia sinensis flower extract, and a Camellia sinensis seed extract as active ingredients, in a weight ratio of 4-12:0.3-4:0.3-4. The composition contains the Camellia sinensis leaf extract and the Camellia sinensis flower and seed extracts in a weight ratio of 4-12:0.2-8. The metabolic syndrome is a glucoside metabolic syndrome or a lipid metabolic syndrome. The metabolic syndrome includes one or more among obesity, hyperlipidemia, type 2 diabetes, arteriosclerosis, myocardial infarction, and angina pectoris. The composition is a pharmaceutical composition. [Reference numerals] (AA) Mixture of Camellia sinensis leaf, flower, and seed extracts; (BB) Camellia sinensis flower extract; (CC) Camellia sinensis seed extract; (DD) Camellia sinensis leaf extract
Abstract:
PURPOSE: A composition containing syringaresinol as an active ingredient is provided to suppress melanogenesis and tyrosinase activity, and to ensure anti-oxidation and skin whitening. CONSTITUTION: A composition for skin whitening contains 0.001-20wt% of syringaresinol as an active ingredient. The composition enhances the brightness and uniformity of skin color. The composition treats hyperpigmentation. The hyperpigmentation includes melasma, seborrheic keratosis, freckle, nevus, and dark circle. Syringaresinol is contained in an extract selected among a lindseed extract, a Phellodendri cortex extract, an Acanthopanacis cortex extract, a sesame extract, and a ginseng fruit extract. The composition is used for removing dead skin cells and promotes dead skin cell turn over. [Reference numerals] (AA) Syringaresinol
Abstract:
PURPOSE: A composition containing soybean extract, Biota orientalis extract, linseed extract, or Glycyrrhiza uralensis extract is provided to improve blood circulation and to promote hair growth. CONSTITUTION: A composition for preventing hair loss or promoting hair growth contains soybean extract, Biota orientalis extract, linseed extract, or Glycyrrhiza uralensis extract as an active ingredient. A composition for promoting hair growth contains soybean extract, Biota orientalis extract, linseed extract, or Glycyrrhiza uralensis extract as an active ingredient. The extract is prepared using C1-C5 alcohols. [Reference numerals] (AA) Control group; (BB) Comparative embodiment; (CC) Embodiment 5
Abstract:
PURPOSE: A composition containing soybean extract is provided to supply nutrient to epidermal cells of hair root, to prevent hair loss, and to promote hair growth. CONSTITUTION: A composition for preventing hair loss or promoting hair growth contains 0.001-90 wt% of soybean extract as an active ingredient, prepared by extracting 1-70%(v/v) C1-C5 alcohol. A composition for enhancing hair health contains the soybean extract as an active ingredient. The C1-C5 alcohols are methanol, ethanol, isopropyl alcohol, n-propyl alcohol, n-butanol, or isobutanol. The composition is applied to a cosmetic, food, or pharmaceutical composition. [Reference numerals] (AA) Control group; (BB) Embodiment 4; (CC) Embodiment 2
Abstract:
PURPOSE: An antithrombotic composition containing a fraction of colored extract is provided to treat circulatory system diseases such as hypertension and diabetes. CONSTITUTION: An antithrombotic composition contains a resin fraction of colored bean extract isolated using water, C1-C5 alcohol, or mixture thereof. The concentration of C1-C5 is 1-40%(v/v) and includes methanol, ethanol, isopropyl alcohol, n-propyl alcohol, n-butanol, or isobutanol. A pharmaceutical composition for relieving or treating vascular diseases contains the composition as an active ingredient, containing the resin fraction. A health food composition for preventing or relieving vascular diseases contains the composition as an active ingredient, containing the resin fraction. The vascular diseases are obesity, diabetes, stroke, cerebral hemorrhage, arteriosclerosis, angina, myocardial infarction, hypertension, anemia, or hyperlipidemia.
Abstract:
PURPOSE: A composition for improving the blood circulation and curing cold hands and feet, containing a fermented tea extract is provided to secure the excellent taste and flavor of the composition. CONSTITUTION: A composition for improving the blood circulation and curing cold hands and feet is obtained by the following steps: preparing fermented liquid containing tea; injecting strains originated from fermented soybean plate into the fermented liquid; and fermenting the fermented liquid. The tea is selected from the group consisting of green tea, white tea, oolong tea, black tea, puer tea, and persimmon leaf tea.
Abstract:
본 발명은 글리코겐 합성효소 키나아제 3β 활성 억제제로서의 에피갈로카테킨 갈레이트(Epigallocatechin gallate, EGCG)를 함유하는 조성물에 관한 것으로, 보다 상세하게는 글리코겐 합성효소 키나아제 3β의 발현 또는 그 활성을 억제함으로써 글리코겐 합성을 증가시켜 제 2형 당뇨병의 치료에 유용하게 사용될 수 있는 에피갈로카테킨 갈레이트를 유효성분으로 함유하는 조성물에 관한 것이다. 에피갈로카테킨 갈레이트, 글리코겐 합성효소 키나아제 3β, 근육세포, 제 2형 당뇨병
Abstract:
본 발명은 티로시나제 저해 활성을 가지는 펩티드, 그 제조방법, 및 이를 함유하는 피부 외용제 조성물에 관한 것이다. 보다 상세하게는 화학적으로 합성된 펩티드 라이브러리(펩티드 무작위 서열 혼합물)로부터 선별되는 네개의 아미노산으로 이루어진 펩티드로서, 구체적으로 첫번째 아미노산 및 두번째 아미노산이 티로신 또는 트립토판에서 선택되고, 세번째 아미노산이 트립토판, 네번째 아미노산이 아르기닌으로 구성되는 서열을 가지는, 티로시나제 억제 작용을 가지는 펩티드 및 그 제조방법에 관한 것이다. 또한, 본 발명은 상기 펩티드를 유효 성분으로 함유한 피부 외용제 조성물에 관한 것이다. 본 발명에 의한 멜라닌 생성 억제 펩티드는 멜라닌 생성 세포에 존재하는 티로시나제의 활성을 억제하며, 세포에도 매우 안전하다. 따라서, 상기 펩티드를 유효 성분으로 함유하는 본 발명의 피부 외용제 조성물은, 멜라닌 생성의 효과적인 억제로 피부 미백 효과에 있어 탁월하며, 기미, 주근깨, 태양 광선에 의한 피부 그을림 등의 피부 색소 침착을 효과적으로 개선 및 방지할 수 있다. 미백, 멜라닌 생성 억제, 아미노산 서열, 펩티드, 티로시나제, 피부 외용제 조성물