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公开(公告)号：KR1020100058866A
公开(公告)日：2010-06-04
申请号：KR1020080117431
申请日：2008-11-25
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition for anti-dandruff is provided to maintain pH concentration from 4.0 to 6.0 and to ensure safety to scalp. CONSTITUTION: A hair cosmetic composition for anti-dandruff contains 0.01-2.0 weight% of Zn-pyrithione of chemical formula 1 and 0.01-5.0 weight% of trihydroxystearin of chemical formula 2 as active ingredient. The acidity of the composition is maintained in pH 4.0-6.0. The pH adjusting agent is stearic acid citric acid, acetic acid, lactic acid, aspartic acid, or stearic acid. The hair cosmetic composition is used in the form of shampoo, rinse, hair tonic, or hair treatment.
Abstract translation: 目的：提供抗头皮屑的化妆品组合物，以将pH浓度从4.0保持至6.0，并确保头皮的安全性。 构成：用于防头皮屑的头发化妆品组合物含有0.01-2.0重量％的化学式1的锌 - 吡啶硫酮和0.01-5.0重量％的化学式2的三羟基硬脂酸酯作为活性成分。 组合物的酸度保持在pH 4.0-6.0。 pH调节剂是硬脂酸柠檬酸，乙酸，乳酸，天冬氨酸或硬脂酸。 头发化妆品组合物以洗发剂，漂洗剂，滋补剂或头发处理的形式使用。
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公开(公告)号：KR1020100046668A
公开(公告)日：2010-05-07
申请号：KR1020080105619
申请日：2008-10-28
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: An evaluation method is provided to objectively measure the relief effect of sensory skin irritation by quantifying the relief effect of sensory skin irritation about various anti-irritants through the change of concrete threshold. CONSTITUTION: A sensory skin irritation relief effect evaluation method comprises a step of measuring the change of a threshold before and after spreading an anti-irritant to a stimulus applied to the skin sensory nerve. The evaluation method quantitatively measures the change of the threshold by using a device. The evaluation method measures the change of the threshold value about a stimulus applied to at least one skin sensory nerve which is selected in a group which includes Aα, Aβ, Aδ, and C-fiber type. The evaluation method measures the change of the threshold value about a stimulus which is applied to the skin sensory nerve of Aδ or C-fiber type.
Abstract translation: 目的：通过改变混凝土阈值，量化消除各种抗刺激剂对皮肤刺激的缓解作用，提供评估方法，客观地测量感觉皮肤刺激的缓解作用。 构成：感官皮肤刺激缓解效果评估方法包括测量在将抗刺激剂涂抹于皮肤感觉神经的刺激之前和之后的阈值变化的步骤。 评价方法通过使用装置定量地测量阈值的变化。 评估方法测量关于施加到包括Aα，Aβ，Aδ和C纤维类型的组中选择的至少一种皮肤感觉神经的刺激的阈值变化。 评估方法测量施加于Aδ或C纤维类型的皮肤感觉神经的刺激的阈值变化。
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公开(公告)号：KR1020090020834A
公开(公告)日：2009-02-27
申请号：KR1020070085431
申请日：2007-08-24
Applicant: (주)아모레퍼시픽
Abstract: An in vitro skin sensitization test method is provided to rapidly analyze the skin sensitization-inducing possibility of material through the cell derived from the human body without use of animal, and classify and grade the skin sensitization-inducing possibility, thereby easily finding out the procedure required for the following process. The in vitro skin sensitization test method comprises the steps of: determining the treatment concentration of the estimation target material for the skin sensitization-inducing test; contacting the determined concentration of the estimation target material with the human origin cell, and culturing the cell; detecting CD86, CD54 and CD83 as costimulatory molecule, expressed from the cultured human origin cell; indexing the detected costimulatory molecules; grading and classifying the indexed detection amount; and determining the estimation target material as the skin sensitization-inducing material when the classified detection amount is the risk grade.
Abstract translation: 提供体外皮肤致敏试验方法，以快速分析通过源自人体的细胞的材料的皮肤敏化诱导可能性，而不使用动物，并分类和分级皮肤致敏诱导的可能性，从而容易地找出程序 需要以下过程。 体外皮肤致敏试验方法包括以下步骤：确定用于皮肤致敏诱导试验的估计目标材料的处理浓度; 将所测定的所述目标物质浓度与所述人源细胞接触，培养所述细胞; 从培养的人源细胞中检测CD86，CD54和CD83作为共刺激分子; 索引检测到的共刺激分子; 索引检测量分级和分类; 以及当所述分类检测量为风险等级时，将所述估计目标材料确定为所述皮肤致敏诱导材料。
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公开(公告)号：KR100862274B1
公开(公告)日：2008-10-09
申请号：KR1020070039895
申请日：2007-04-24
Applicant: (주)아모레퍼시픽
Abstract: A method for evaluating human skin damage by detecting furrows of human skin is provided to evaluate damage to human skin caused by a body washer by visualizing and quantifying the furrows. A method for evaluating human skin damage by detecting furrows of human skin includes the steps of: taking an image of the furrows by the skin damage by photographing human skin using an in vivo laser confocal microscopy; setting analysis section of the image of the furrows; visualizing the furrows of the human skin by using an image analysis program; and quantifying the number of pixels by measuring an area of the furrows in the analysis section.
Abstract translation: 提供了一种通过检测人体皮肤的沟槽来评价人体皮肤损伤的方法，以通过可视化和量化沟槽来评估由人体垫圈引起的对人体皮肤的损伤。 通过检测人皮肤的沟槽来评估人体皮肤损伤的方法包括以下步骤：通过使用体内激光共焦显微镜拍摄人体皮肤，通过皮肤损伤拍摄犁沟的图像; 犁沟图像的设定分析部分; 通过使用图像分析程序可视化人体皮肤的沟槽; 以及通过测量分析部分中的沟槽的面积来量化像素的数量。
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Patent Agency Ranking
公开(公告)号：KR1020160116871A
公开(公告)日：2016-10-10
申请号：KR1020150045226
申请日：2015-03-31
Applicant: (주)아모레퍼시픽
Abstract: 본명세서에는항균상승효과를갖는항균조성물이개시된다. 상기항균조성물은양이온계면활성제및 음이온계면활성제중 하나이상을포함하는계면활성제와 EDTA를포함함으로써, 계면활성제의낮은농도에서도균의활성및 증식을억제하는효과가있다.
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公开(公告)号：KR101543181B1
公开(公告)日：2015-08-07
申请号：KR1020140124117
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
Abstract: 민감성피부에대해서특이적으로유전자발현량이증가또는억제되는바이오마커가개시된다. 상기민감성피부에특이적인바이오마커를이용하여민감성피부진단키트및 자극감완화제의스크리닝방법등에활용할수 있다.
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公开(公告)号：KR101543179B1
公开(公告)日：2015-08-07
申请号：KR1020140124114
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
Abstract: 민감성피부에대해서특이적으로유전자발현량이증가또는억제되는바이오마커가개시된다. 상기민감성피부에특이적인바이오마커를이용하여민감성피부진단키트및 자극감완화제의스크리닝방법등에활용할수 있다.
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公开(公告)号：KR101543175B1
公开(公告)日：2015-08-07
申请号：KR1020140124110
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
Abstract: 민감성피부에대해서특이적으로유전자발현량이증가또는억제되는바이오마커가개시된다. 상기민감성피부에특이적인바이오마커를이용하여민감성피부진단키트및 자극감완화제의스크리닝방법등에활용할수 있다.
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公开(公告)号：KR1020140130378A
公开(公告)日：2014-11-10
申请号：KR1020140124108
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
CPC classification number: C12Q1/6844 , C12Q1/6813
Abstract: 민감성 피부에 대해서 특이적으로 유전자 발현량이 증가 또는 억제되는 바이오 마커가 개시된다. 상기 민감성 피부에 특이적인 바이오 마커를 이용하여 민감성 피부 진단 키트 및 자극감 완화제의 스크리닝 방법 등에 활용할 수 있다.
Abstract translation: 公开了具有基因表达的生物标志物，其对于敏感性皮肤特异性地增加或减少。 敏感皮肤特异性的生物标志物用于敏感皮肤的这种诊断试剂盒和刺激释放剂的筛选方法。 所述诊断试剂盒包含：一种或多种作为NFκB1转录因子多核苷酸的多核苷酸或其片段，其中所述片段包含十个或更多个连续核苷酸，或与片段互补的多核苷酸和多核苷酸; 和具有多核苷酸结合表面的固体支持物。
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