시험관내 피부 감작성 평가 방법
    34.
    发明授权
    시험관내 피부 감작성 평가 방법 有权
    体外皮肤致敏试验方法

    公开(公告)号:KR101349249B1

    公开(公告)日:2014-01-10

    申请号:KR1020070085431

    申请日:2007-08-24

    Abstract: 본 발명은 사람 유래 세포 표면 및 세포배양액에서 발현되는 지표를 측정하여 화장품 원료 또는 기타 물질의 피부 감작성을 평가하는 시험관내 피부 감작성 평가방법과 이 평가방법을 통해 도출된 데이터로부터 물질의 감작성 유발 가능성을 등급화하는 방법에 관한 것이다.
    피부 감작성, CD86, CD54, CD83

    피부자극 및 염증 완화용 조성물
    35.
    发明公开
    피부자극 및 염증 완화용 조성물 有权
    用于减少皮肤刺激和炎症的组合物

    公开(公告)号:KR1020100060679A

    公开(公告)日:2010-06-07

    申请号:KR1020080119374

    申请日:2008-11-28

    CPC classification number: A61K8/97 A61K8/361 A61Q19/00

    Abstract: PURPOSE: A composition containing plant extract having different irritation relief mechanism is provided to suppress prostaglandin-E2 and activate secretion of alpha-melanocyte stimulating hormone. CONSTITUTION: A composition for relieving skin irritation and inflammation contains Rubus Idaeus fruit extract, Mentha piperita extract, and Boerhavia diffusa Root Extract as an active ingredient. The weight ration of the mixture is 1-4:1-8:1-8. The active ingredient relieves skin irritation and inflammation by retinoic acid or sldium lauryl sulfate. The composition is used in the form of an external use skin formulation. The composition is used in the form of skin, lotion, massage cream, nutrition cream, pack, gel, or skin additive cosmetic.

    Abstract translation: 目的:提供含有不同刺激缓解机制的植物提取物的组合物,以抑制前列腺素E2,并激活α-黑素细胞刺激激素的分泌。 构成:用于缓解皮肤刺激和炎症的组合物含有Rubus Idaeus水果提取物,Mentha piperita提取物和Boerhavia diffusa Root Extract作为活性成分。 混合物的重量比为1-4:1-8:1-8。 活性成分通过视黄酸或十二烷基硫酸钠缓解皮肤刺激和炎症。 组合物以外用皮肤制剂的形式使用。 该组合物以皮肤,洗剂,按摩霜,营养霜,包装,凝胶或皮肤添加剂化妆品的形式使用。

    자극완화복합물을 함유하는 자극 완화용 화장료 조성물
    36.
    发明公开
    자극완화복합물을 함유하는 자극 완화용 화장료 조성물 有权
    化妆品组合物含有复合物

    公开(公告)号:KR1020100060599A

    公开(公告)日:2010-06-07

    申请号:KR1020080119251

    申请日:2008-11-28

    CPC classification number: A61K8/97 A61K8/02 A61Q19/00 A61Q19/08

    Abstract: PURPOSE: A cosmetic composition containing Glechoma hederacea extract, peppermint extract, and biosaccharide gum-2 is provided to protect skin from outer irritation and to normalize sensitive skin. CONSTITUTION: A cosmetic composition for relieving irritation contains 0.01-5 weight% of mixture perppermint extract and biosaccharide gum-2 as active ingredients. The cosmetic composition is used in the form of skin, lotion, massage cream, nutrition cream, pack, gel, ointment, gel, cream, patch, or spray. The cosmetic composition further contains active ingredients for skin whitening, anti-aging, or anti-wrinkle.

    Abstract translation: 目的:提供含有Glechoma hederacea提取物,薄荷提取物和生物糖胶-2的化妆品组合物,以保护皮肤免受外部刺激和使皮肤正常化。 构成:用于缓解刺激的化妆品组合物含有0.01-5重量%的混合珍珠提取物和生物糖胶-2作为活性成分。 化妆品组合物以皮肤,洗剂,按摩霜,营养霜,包装,凝胶,软膏,凝胶,霜,贴剂或喷雾剂的形式使用。 化妆品组合物还含有用于皮肤美白,抗衰老或抗皱的活性成分。

    민감성 피부 진단용 바이오 마커 및 이를 이용한 진단 키트
    37.
    发明公开
    민감성 피부 진단용 바이오 마커 및 이를 이용한 진단 키트 有权
    用于预测敏感性皮肤和测试套件的生物标记

    公开(公告)号:KR1020090123049A

    公开(公告)日:2009-12-02

    申请号:KR1020080048930

    申请日:2008-05-27

    CPC classification number: C12Q1/6883 C12Q2600/136

    Abstract: PURPOSE: A biomarker of which expression is specifically decreased or suppressed in the sensitive skin is provided to quickly diagnose sensitive skin and used for screening a relieving agent. CONSTITUTION: A biomarker for diagnosing sensitive skin contains gene of which expression is decreased or increased in the sensitive skin compared to healthy skin or a protein encoding the gene. A method for screening a relieving agent of sensitivity comprises: a step of conjugating a candidate agent to a protein encoded by a gene of which expression is increased or decreased in the sensitive skin; and a step of confirming the suppression of protein activity.

    Abstract translation: 目的:提供敏感皮肤中特异性降低或抑制表达的生物标志物,以快速诊断敏感皮肤并用于筛选缓解剂。 构成:与健康皮肤或编码该基因的蛋白质相比,用于诊断敏感皮肤的生物标志物含有敏感皮肤中表达降低或增加的基因。 用于筛选敏感性缓释剂的方法包括:将候选试剂与由敏感皮肤中表达增加或减少的基因编码的蛋白质缀合的步骤; 以及确认蛋白质活性抑制的步骤。

    코지산 유도체와 그 제조방법, 및 이를 함유한 미백화장료 조성물
    38.
    发明公开
    코지산 유도체와 그 제조방법, 및 이를 함유한 미백화장료 조성물 有权
    醇酸衍生物,其制备方法和含有该组合物的化妆品组合物

    公开(公告)号:KR1020040059626A

    公开(公告)日:2004-07-06

    申请号:KR1020020085310

    申请日:2002-12-27

    Abstract: PURPOSE: Kojic acid derivatives, a preparation method thereof, and a whitening cosmetic composition containing the same are provided, thereby inhibiting melanine formation, and improving stability of kojic acid derivatives, so that the kojic acid derivatives can be stably applied to the cosmetic composition. CONSTITUTION: The kojic acid derivatives represented by formula (I) are provided, wherein R is CH2-CH2 , CH=CH, CH2-CH2-CH2 , CH2-CH-(CH3)-CH2 , CH2-CH(CH3)2-CH2 , C6H4-1,4-, C6H4-1,3-, CH=CHCH=CH, C5H3N-2,5- or C5H3N-3,5-. The method for preparing the kojic acid derivatives of formula (I) comprises the steps of: (A) reacting dicarboxylic acid with chloride to prepare acid chloride of dicarboxylic acid; and (B) reacting the acid chloride of dicarboxylic acid with two molecules of kojic acid to form an ester bond between them, wherein chloride is selected from thionyl chloride, oxalyl chloride, phosphorous trichloride and phosphorous oxychloride. The whitening cosmetic composition contains 0.01 to 20 wt.% of kojic acid derivatives.

    Abstract translation: 目的:提供曲酸酸衍生物及其制备方法和含有该化合物的美白化妆品组合物,从而抑制双酚A的形成,提高曲酸衍生物的稳定性,从而可以将曲酸衍生物稳定地用于化妆品组合物。 组成:提供由式(I)表示的曲酸衍生物,其中R是CH 2 -CH 2,CH = CH,CH 2 -CH 2 -CH 2,CH 2 -CH(CH 3)-CH 2,CH 2 -CH(CH 3)2 - CH2,C6H4-1,4-,C6H4-1,3-,CH = CHCH = CH,C5H3N-2,5或C5H3N-3,5。 制备式(I)曲酸衍生物的方法包括以下步骤:(A)使二羧酸与氯化物反应制备二羧酸的酰氯; 和(B)使二羧酸的酰氯与两分子曲酸反应以在它们之间形成酯键,其中氯化物选自亚硫酰氯,草酰氯,三氯化磷和三氯氧化磷。 美白化妆品组合物含有0.01-20重量%的曲酸衍生物。

Patent Agency Ranking