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公开(公告)号：KR1020140044454A
公开(公告)日：2014-04-15
申请号：KR1020120110418
申请日：2012-10-05
Applicant: (주)아모레퍼시픽
IPC: A61K31/225 , A61K31/215 , A61K31/37 , A61P17/00
CPC classification number: A61K31/225 , A61K8/362 , A61K8/375 , A61K8/498 , A61K8/66 , A61K31/353 , A61Q19/00 , A61Q19/08 , A61K2300/00
Abstract: The present invention relates to an anti-aging or skin moisturizing composition. The composition according to the present invention comprises a material, as an active ingredient, for controlling the expression of ABH antigen, and therefore, has superior anti-aging and skin moisturizing effects. Further, the present invention can be effectively used in reducing or alleviating wrinkles by inhibiting the expression of MMP-1.
Abstract translation: 本发明涉及抗衰老或皮肤保湿组合物。 根据本发明的组合物包含用作控制ABH抗原表达的材料作为活性成分，因此具有优异的抗衰老和皮肤保湿作用。 此外，通过抑制MMP-1的表达，本发明可以有效地用于减少或减轻皱纹。
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公开(公告)号：KR101543181B1
公开(公告)日：2015-08-07
申请号：KR1020140124117
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
Abstract: 민감성피부에대해서특이적으로유전자발현량이증가또는억제되는바이오마커가개시된다. 상기민감성피부에특이적인바이오마커를이용하여민감성피부진단키트및 자극감완화제의스크리닝방법등에활용할수 있다.
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公开(公告)号：KR101543179B1
公开(公告)日：2015-08-07
申请号：KR1020140124114
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
Abstract: 민감성피부에대해서특이적으로유전자발현량이증가또는억제되는바이오마커가개시된다. 상기민감성피부에특이적인바이오마커를이용하여민감성피부진단키트및 자극감완화제의스크리닝방법등에활용할수 있다.
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公开(公告)号：KR101543175B1
公开(公告)日：2015-08-07
申请号：KR1020140124110
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
Abstract: 민감성피부에대해서특이적으로유전자발현량이증가또는억제되는바이오마커가개시된다. 상기민감성피부에특이적인바이오마커를이용하여민감성피부진단키트및 자극감완화제의스크리닝방법등에활용할수 있다.
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公开(公告)号：KR1020140130378A
公开(公告)日：2014-11-10
申请号：KR1020140124108
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
CPC classification number: C12Q1/6844 , C12Q1/6813
Abstract: 민감성 피부에 대해서 특이적으로 유전자 발현량이 증가 또는 억제되는 바이오 마커가 개시된다. 상기 민감성 피부에 특이적인 바이오 마커를 이용하여 민감성 피부 진단 키트 및 자극감 완화제의 스크리닝 방법 등에 활용할 수 있다.
Abstract translation: 公开了具有基因表达的生物标志物，其对于敏感性皮肤特异性地增加或减少。 敏感皮肤特异性的生物标志物用于敏感皮肤的这种诊断试剂盒和刺激释放剂的筛选方法。 所述诊断试剂盒包含：一种或多种作为NFκB1转录因子多核苷酸的多核苷酸或其片段，其中所述片段包含十个或更多个连续核苷酸，或与片段互补的多核苷酸和多核苷酸; 和具有多核苷酸结合表面的固体支持物。
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Patent Agency Ranking
公开(公告)号：KR1020140123032A
公开(公告)日：2014-10-21
申请号：KR1020140124111
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
CPC classification number: C12Q1/6844 , C12Q1/6813
Abstract: Disclosed is a biomarker having the amount of gene expression be specifically increased or reduced for sensitive skin. The biomarker specific to sensitive skin is used in such a diagnostic kit for sensitive skin and a screening method of an abirritant. The biomarker for diagnosis of sensitive skin according to the present invention one or more gene selected from a group composed of HLA-C, TCEA1, IGHA1, TFRC, S100A8, LOC652128, SERPINB13, EHF, FLJ10781, TP63, CDH1, TNFRSF19, GM2A, FKBP5, PI3, PSPH, HORMAD1, SPRR2G, and ACTR2 or a group composed of KBTBD10, TTN, ACTA1, MYBPC1, MB, MYOZ1, TPM1, CA3, CASQ1, ENO3, RBP4, GYG2, PPP1R1A, PYGM, G0S2, NEB, H19, LIPE, PLIN, H19, GPAM, FABP4, CIDEC, LPL, PCK1, ADIPOQ, PDE3B, ACVR1C, LPL, FABP4, DKFZP761N09121, TNMD, ATP6V1B1, C8orf22, and CRISP3.
Abstract translation: 公开了对敏感性皮肤具有特异性增加或减少的基因表达量的生物标志物。 敏感性皮肤特异性生物标志物用于这种用于敏感性皮肤的诊断试剂盒和中枢刺激剂的筛选方法。 根据本发明的用于诊断敏感性皮肤的生物标志物选自由HLA-C，TCEA1，IGHA1，TFRC，S100A8，LOC652128，SERPINB13，EHF，FLJ10781，TP63，CDH1，TNFRSF19，GM2A， FKBP5，PI3，PSPH，HORMAD1，SPRR2G和ACTR2或由KBTBD10，TTN，ACTA1，MYBPC1，MB，MYOZ1，TPM1，CA3，CASQ1，ENO3，RBP4，GYG2，PPP1R1A，PYGM，G0S2，NEB，H19 ，LIPE，PLIN，H19，GPAM，FABP4，CIDEC，LPL，PCK1，ADIPOQ，PDE3B，ACVR1C，LPL，FABP4，DKFZP761N09121，TNMD，ATP6V1B1，C8orf22和CRISP3。
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公开(公告)号：KR1020140118972A
公开(公告)日：2014-10-08
申请号：KR1020140124107
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
CPC classification number: C12Q1/6844 , C12Q1/6813
Abstract: Disclosed is a biomarker by which the amount of gene expression is increased or the gene expression is inhibited specifically with respect to sensitive skin. The biomarker can be used for a kit for testing sensitive skin and a method for screening an agent for alleviating irritation. The test kit includes: a polynucleotide of a TNFRSF19 gene, one or more polynucleotides which are fragments of the polynucleotide of the TNFRSF19 gene and include 10 or more serial nucleotides, or a polynucleotide complementary to the polynucleotide stated earlier and fragments thereof; and a solid scaffold having the surface on which the polynucleotides are bound.
Abstract translation: 公开了一种基因表达量增加或相对于敏感皮肤特异性抑制基因表达的生物标志物。 生物标志物可用于测试敏感性皮肤的试剂盒和用于筛选试剂以减轻刺激性的方法。 测试试剂盒包括：TNFRSF19基因的多核苷酸，一种或多种多核苷酸，其是TNFRSF19基因的多核苷酸的片段，并且包括10个或更多个序列核苷酸，或与前述多核苷酸互补的多核苷酸及其片段; 和具有结合多核苷酸的表面的固体支架。
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公开(公告)号：KR101449129B1
公开(公告)日：2014-10-08
申请号：KR1020120110418
申请日：2012-10-05
Applicant: (주)아모레퍼시픽
IPC: A61K31/225 , A61K31/215 , A61K31/37 , A61P17/00
CPC classification number: A61K31/225 , A61K8/362 , A61K8/375 , A61K8/498 , A61K8/66 , A61K31/353 , A61Q19/00 , A61Q19/08 , A61K2300/00
Abstract: 본 발명은 항노화용 또는 보습용 조성물에 관한 것이다. 본 발명에 따른 조성물은 ABH 항원의 발현을 조절하는 물질을 유효성분으로 함유하여, 우수한 항노화 및 보습 효과를 가진다. 본 발명의 조성물은 또한 MMP-1 발현을 억제하여 주름의 완화 또는 개선을 위해 유용하게 사용될 수 있다.
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公开(公告)号：KR1020140089505A
公开(公告)日：2014-07-15
申请号：KR1020140081131
申请日：2014-06-30
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
Abstract: The present invention discloses a biomarker of which a gene expression level increases or decreases specifically with respect to sensitive skin. The biomarker specific to sensitive skin can be applied to a kit for identifying sensitive skin and a screening method of an irritation reliever. The biomarker for identifying sensitive skin includes one or more genes selected from a group constituted by HLA-C, TCEA1, IGHA1, TFRC, S100A8, LOC652128, SERPINB13, EHF, FLJ10781, TP63, CDH1, TNFRSF19, GM2A,FKBP5, PI3, PSPH, HORMAD1, SPRR2G and ACTR2.
Abstract translation: 本发明公开了相对于敏感性皮肤特异性地基因表达水平升高或降低的生物标志物。 敏感皮肤特异性的生物标志物可用于鉴定敏感皮肤的试剂盒和刺激缓解剂的筛选方法。 识别敏感皮肤的生物标志物包括选自HLA-C，TCEA1，IGHA1，TFRC，S100A8，LOC652128，SERPINB13，EHF，FLJ10781，TP63，CDH1，TNFRSF19，GM2A，FKBP5，PI3，PSPH组成的组中的一种或多种基因 ，HORMAD1，SPRR2G和ACTR2。
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公开(公告)号：KR101543183B1
公开(公告)日：2015-08-07
申请号：KR1020140124119
申请日：2014-09-18
Applicant: (주)아모레퍼시픽 , 서울대학교산학협력단
Abstract: 민감성피부에대해서특이적으로유전자발현량이증가또는억제되는바이오마커가개시된다. 상기민감성피부에특이적인바이오마커를이용하여민감성피부진단키트및 자극감완화제의스크리닝방법등에활용할수 있다.
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