Abstract:
본 발명은 스티그마스테릴 헤미숙시네이트를 포함한 지질-기반 약물 전달체및 이를 함유하는 피부 외용제 조성물에 관한 것으로, 더욱 상세하게는 스티그마스테릴 헤미숙시네이트 또는 그의 염을 사용하여 제조한 리포좀, 마이크로에멀젼 또는 나노에멀젼으로서 산성도 변화에 대하여 민감한 감응성을 지니고 있어 내상에 함입되는 생리활성성분을 생체내에서 효과적으로 방출하여 전달체로서의 효과를 증진시킬 수 있도록 제조한 지질-기반 약물 전달체 및 이를 함유하는 피부 외용제 조성물에 관한 것이다. 스티그마스테릴 헤미숙시네이트*산성도 민감성*리포좀*마이크로에멀젼*나노에멀젼*약물 전달체
Abstract:
Iron oxide/polymer colloidal nano-composites, a preparation process thereof, and cosmetic compositions containing the same nano-composites are provided to stably exhibit the magnetic properties of nano-composites by inhibiting the coagulation and precipitation of magnetic particles in cosmetic composition, so that blood circulation in the skin is promoted. The iron oxide/polymer colloidal nano-composites are provided, wherein iron oxide nano-particles are bound to the skin of the porous polymer particles, wherein the amount of iron oxide nano-particles is 0.001-30 wt.% based on the total weight of the polymer; the particle size of the porous polymer particles is 0.01-1,000mum; the surface area of the porous polymer particles is 10-1000 m^2/g; the porous polymer particles have pores of 1-10nm; and the porous polymer particles have functional groups for inducing deposition of iron oxide nano-particles. The iron oxide/polymer colloidal nano-composites are prepared by (1) dissolving monomer, cross-linking agent and initiating agent in solvent, (2) emulsifying the solution of step(1) in the presence of dispersion stabilizing agent, (3) polymerizing the emulsion prepared in step(2), removing solvent from the emulsion, and recovering the porous polymer particles, and (4) binding the iron oxide prepared by oxidizing the iron salt with an oxidizing agent to the surface of the porous polymer particles.
Abstract:
PURPOSE: Provided are a method for producing or testing skin care cosmetics by biophoton measurement and skin care cosmetics produced or tested thereby. Therefore, biological active components are screened, and skin care cosmetics containing them are produced. CONSTITUTION: A method for producing or testing skin care cosmetics by biophoton measurement comprises the steps of: measuring biophoton by biological active components of the functional cosmetics; determining the usage of the biological active components; and manufacturing skin care cosmetics containing then when it is determined to be useful.