公开(公告)号：KR1020100060679A

公开(公告)日：2010-06-07

申请号：KR1020080119374

申请日：2008-11-28

Applicant: (주)아모레퍼시픽

Inventor： 조선아 ,  이은영 ,  안수선 ,  김한성 ,  이태룡

IPC: A61K36/534 ,  A61P17/00

CPC classification number: A61K8/97 ,  A61K8/361 ,  A61Q19/00

Abstract: PURPOSE: A composition containing plant extract having different irritation relief mechanism is provided to suppress prostaglandin-E2 and activate secretion of alpha-melanocyte stimulating hormone. CONSTITUTION: A composition for relieving skin irritation and inflammation contains Rubus Idaeus fruit extract, Mentha piperita extract, and Boerhavia diffusa Root Extract as an active ingredient. The weight ration of the mixture is 1-4:1-8:1-8. The active ingredient relieves skin irritation and inflammation by retinoic acid or sldium lauryl sulfate. The composition is used in the form of an external use skin formulation. The composition is used in the form of skin, lotion, massage cream, nutrition cream, pack, gel, or skin additive cosmetic.

Abstract translation: 目的：提供含有不同刺激缓解机制的植物提取物的组合物，以抑制前列腺素E2，并激活α-黑素细胞刺激激素的分泌。 构成：用于缓解皮肤刺激和炎症的组合物含有Rubus Idaeus水果提取物，Mentha piperita提取物和Boerhavia diffusa Root Extract作为活性成分。 混合物的重量比为1-4：1-8：1-8。 活性成分通过视黄酸或十二烷基硫酸钠缓解皮肤刺激和炎症。 组合物以外用皮肤制剂的形式使用。 该组合物以皮肤，洗剂，按摩霜，营养霜，包装，凝胶或皮肤添加剂化妆品的形式使用。

公开(公告)号：KR1020100060599A

公开(公告)日：2010-06-07

申请号：KR1020080119251

申请日：2008-11-28

Applicant: (주)아모레퍼시픽

Inventor： 이은영 ,  조선아 ,  안수선 ,  김한성 ,  이태룡

IPC: A61K8/97 ,  A61Q19/00

CPC classification number: A61K8/97 ,  A61K8/02 ,  A61Q19/00 ,  A61Q19/08

Abstract: PURPOSE: A cosmetic composition containing Glechoma hederacea extract, peppermint extract, and biosaccharide gum-2 is provided to protect skin from outer irritation and to normalize sensitive skin. CONSTITUTION: A cosmetic composition for relieving irritation contains 0.01-5 weight% of mixture perppermint extract and biosaccharide gum-2 as active ingredients. The cosmetic composition is used in the form of skin, lotion, massage cream, nutrition cream, pack, gel, ointment, gel, cream, patch, or spray. The cosmetic composition further contains active ingredients for skin whitening, anti-aging, or anti-wrinkle.

Abstract translation: 目的：提供含有Glechoma hederacea提取物，薄荷提取物和生物糖胶-2的化妆品组合物，以保护皮肤免受外部刺激和使皮肤正常化。 构成：用于缓解刺激的化妆品组合物含有0.01-5重量％的混合珍珠提取物和生物糖胶-2作为活性成分。 化妆品组合物以皮肤，洗剂，按摩霜，营养霜，包装，凝胶，软膏，凝胶，霜，贴剂或喷雾剂的形式使用。 化妆品组合物还含有用于皮肤美白，抗衰老或抗皱的活性成分。

公开(公告)号：KR1020090016595A

公开(公告)日：2009-02-16

申请号：KR1020087030865

申请日：2006-12-08

Applicant: (주)아모레퍼시픽

Inventor： 김형준 ,  김혁 ,  성기사 ,  김대권 ,  성대석 ,  박종희 ,  조선아 ,  김광미 ,  이창훈 ,  김정주

IPC: A61K31/661 ,  C07K14/47 ,  C12Q1/68 ,  A61P17/00

CPC classification number: C12Q1/18 ,  G01N33/92 ,  G01N2405/08 ,  G01N2800/202 ,  A61K31/661 ,  C07K14/47

Abstract: A sphingosylphosphorylcholine(SPC) antagonist is provided to prevent and treat diseases related to the expression decrease of anti-bacterial peptide such as atopic dermatitis, and screen the SPC antagonist by analyzing the expression recover of gene or protein of the anti-bacterial peptide. The sphingosylphosphorylcholine(SPC) antagonist manufactures the medicine for restoring the expression of anti-bacterial peptide back to the normal level in mammal requiring the expression restoration of anti-bacterial peptide. The screening method of the sphingosylphosphorylcholine(SPC) antagonist comprises the steps of: treating the object with sphingosylphosphorylcholine or its derivative to inhibit expression of anti-bacterial peptide; and treating the object with the SPC antagonist candidate material, and analyzing the expression restoration level of the anti-bacterial peptide in the object.

Abstract translation: 提供鞘糖基磷酰胆碱（SPC）拮抗剂以预防和治疗与抗细菌肽如特应性皮炎的表达降低相关的疾病，并通过分析抗细菌肽的基因或蛋白质的表达恢复来筛选SPC拮抗剂。 鞘氨醇磷酰胆碱（SPC）拮抗剂在需要抗菌肽表达恢复的哺乳动物中制备了将抗菌肽的表达恢复至正常水平的药物。 鞘氨醇磷酰胆碱（SPC）拮抗剂的筛选方法包括以下步骤：用鞘糖基磷酰胆碱或其衍生物处理物体以抑制抗菌肽的表达; 并用SPC拮抗剂候选物质处理对象，分析对象中抗菌肽的表达恢复水平。

公开(公告)号：KR1020080050760A

公开(公告)日：2008-06-10

申请号：KR1020060121432

申请日：2006-12-04

Applicant: (주)아모레퍼시픽

Inventor： 조선아 ,  이창훈 ,  김광미 ,  김대권 ,  김형준 ,  성기사 ,  김혁 ,  김정주 ,  김수열

IPC: A61K31/351 ,  A61P41/00

CPC classification number: A61K31/7008 ,  A61K9/06 ,  A61K9/10 ,  A61K9/20 ,  A61K9/48

Abstract: A hexosamine derivative is provided to show excellent intra-abdominal fibrinous adhesion inhibitory activity, thereby being usefully used for preventing or treating post-operative adhesion. A pharmaceutical composition for preventing or treating post-operative adhesion such as intra-abdominal fibrinous adhesion comprises a hexosamine compound represented by a formula(1) or a pharmaceutically acceptable salt thereof as an active ingredient, wherein the active ingredient is selected from the group consisting of galactosamine, D-(+)-glucosamine hydrochloride, and D-(+)-galactosamine hydrochloride.

Abstract translation: 提供了一种己糖胺衍生物以显示优异的腹内纤维粘附抑制活性，从而有效地用于预防或治疗术后粘连。 用于预防或治疗术后粘连（例如腹内纤维粘连）的药物组合物包含由式（1）表示的己糖胺化合物或其药学上可接受的盐作为活性成分，其中活性成分选自 的半乳糖胺，D - （+） - 葡糖胺盐酸盐和D - （+） - 半乳糖胺盐酸盐。

公开(公告)号：KR100776755B1

公开(公告)日：2007-11-28

申请号：KR1020060040588

申请日：2006-05-04

Applicant: (주)아모레퍼시픽

Inventor： 김대권 ,  성대석 ,  김광미 ,  김형준 ,  한지숙 ,  김혁 ,  성기사 ,  박종희 ,  조선아 ,  이창훈 ,  김정주

IPC: A61K36/9068 ,  A61K36/754

Abstract: 본 발명은 생강, 건강, 오수유 및 초두구로 이루어진 군으로부터 선택된 하나 이상의 추출물을 유효성분으로 함유하는 조성물에 관한 것으로서, 구체적으로 본 발명의 추출물은 뛰어난 가려움증 억제 효과를 나타내어, 염증성 피부염, 아토피성 피부염 등으로부터 유발되는 가려움증의 억제 및 완화용 조성물로 유용하게 이용될 수 있다.
생강, 건강, 오수유, 초두구, 가려움증, 소양증, 피부 외용제