Abstract:
본 발명은 곰피 또는 감태 주정 추출물로부터 분리된 플로로탄닌류를 함유하는 알콜성 간손상에 대한 간보호용 조성물에 관한 것으로, 보다 구체적으로는 곰피 또는 감태 주정 추출물에 함유된 플로로탄닌류가 알콜에 의한 HepG2 간세포 손상에 대하여 간세포 사멸 억제효과를 갖는 간 보호용 조성물에 관한 것이다.
Abstract:
PURPOSE: A Laminaria japonica-derived composition for whitening is provided to suppress melanogenesis in melanoma cells and to be used in a functional cosmetic product, functional food, or pharmaceutical composition for whitening. CONSTITUTION: A cosmetic composition for skin whitening contains Laminaria japonica spirit extract, n-hexane soluble extract, or dichloromethane soluble extract as an active ingredient. A pharmaceutical composition for treating pigmentary disorders contains the Laminaria japonica spirit extract, n-hexane soluble extract, or dichloromethane soluble extract as an active ingredient.
Abstract:
PURPOSE: A hepatoprotection composition containing phlorotannins isolated from Ecklonia stolonifera or Ecklonia cava extract is provided to be used as a pharmaceutical composition for preventing and treating liver diseases. CONSTITUTION: A hepatoprotection composition which suppresses hepatocyte injury due to alcohol contains spirit extract of Ecklonia stolonifera or Ecklonia cava as an active ingredient. A health food composition for hepatoprotection contains the spirit extract of Ecklonia stolonifera or Ecklonia cava as an active ingredient. A pharmaceutical composition for hepatoprotection contains phlorotannin compounds as an active ingredient, isolated and purified from an ethyl acetate fraction of Ecklonia stolonifera or Ecklonia cava. The phlorotannin compounds are eckol, dieckol, dioxynodehydroeckol, phlorofucofuroeckol A, and phlorofucofuroeckol B. [Reference numerals] (AA) Ecklonia stolonifera and Ecklonia cava; (BB) Shade drying; (CC) Powder; (DD) Reflux extraction(repeat three times), using spirit; (EE) Extraction; (FF) Filtering at reduced pressure; (GG) Vacuum concentration, 40°C(removing organic solvent); (HH) Crude extract of Ecklonia stolonifera and Ecklonia cava; (II) Organic solvent soluble fraction(repeat 3-4 times); (JJ) N-hexane soluble extract; (KK) Water soluble fraction; (LL) Dichloromethane soluble extract; (MM) Water soluble fraction; (NN) Ethyl acetate soluble extract; (OO) Water soluble fraction
Abstract:
PURPOSE: A pharmaceutical composition or health food containing Laminaria japonica extract or polyphyrin compounds isolated from the same is provided to prevent or treat diabetic complication. CONSTITUTION: A pharmaceutical composition for preventing and treating diabetic complication contains Laminaria japonicaextract or polyphyrin compounds as an active ingredient. The polypyrincompounds are denoted by chemical formula 1 or 2. The Laminaria japonica extract includes crude extract, ethanol, and non-polar solvent soluble extract. A food composition for preventing and treating diabetes complication contains the extract as an active ingredient.
Abstract:
본 발명은 염증성 질환 치료 또는 예방용 조성물에 관한 것으로, 외톨개모자반(Myagropsis myagroides) 추출물 또는 상기 추출물의 분획물을 유효성분으로 함유하는 염증성 질환의 예방 또는 치료용 약학적 조성물을 제공한다. 본 발명의 외톨개모자반 추출물 또는 이의 분획물은 종래 알려진 푸코잔틴(fucoxanthin)이 전혀 함유되어 있지 않음에도 일산화질소(NO), 프로스타글란딘 E 2 (prostaglandin E 2 , PGE 2 ) 및 염증성 사이토카인의 생성을 억제할 뿐만 아니라 iNOS 및 COX-2이 발현을 효과적으로 억제하는 효과가 있는 바, 염증성 질환의 예방 및 치료에 유용하게 이용될 수 있다.
Abstract:
본 발명은 다시마 추출물 또는 그로부터 분리한 폴피린계 화합물(porpyrin-related compounds)을 함유하는 당뇨성 합병증 억제에 활성을 갖는 약학 조성물 또는 건강 식품에 관한 것으로, 상기 추출물은 알도즈 환원 효소 및 최종당화산물 생성 억제 활성을 나타내고, 천연 약재로서 안전성이 확보되어 있으므로 당뇨성 합병증 예방 또는 치료용 약학조성물과 식품 조성물로로 유용하게 이용될 수 있다.
Abstract:
The present invention relates to an anti-obesity composition derived from gulfweeds. More specifically, provided is an anti-obesity pharmaceutical composition or a functional health food containing an extract of Myagropsis myagroides or a fraction of the same as an active ingredient. The extract or the fraction separated from the same of the present invention is a safe material which has excellent effects in inhibiting fat cell differentiation, fat generation, and fat accumulation and is not cellulotoxic so as to be usefully used as an active ingredient of a pharmaceutical composition or a functional health food for decreasing body fat and treating obesity.