Abstract:
본 발명은 다시마 추출물 또는 그로부터 분리한 폴피린계 화합물(porpyrin-related compounds)을 함유하는 당뇨성 합병증 억제에 활성을 갖는 약학 조성물 또는 건강 식품에 관한 것으로, 상기 추출물은 알도즈 환원 효소 및 최종당화산물 생성 억제 활성을 나타내고, 천연 약재로서 안전성이 확보되어 있으므로 당뇨성 합병증 예방 또는 치료용 약학조성물과 식품 조성물로로 유용하게 이용될 수 있다.
Abstract:
The present invention relates to a pharmaceutical composition or a health food comprising a Laminaria japonica extract or a porpyrin-related compound isolated therefrom which has inhibitory activity for diabetic complications. The extract shows inhibitory activity generation of aldose reductase and advanced glycation end-products and is ensured as a natural medicine; thereby can be used as a pharmaceutical composition and a food composition for preventing or treating the diabetic complications.
Abstract:
PURPOSE: A pharmaceutical composition or health food containing Laminaria japonica extract or polyphyrin compounds isolated from the same is provided to prevent or treat diabetic complication. CONSTITUTION: A pharmaceutical composition for preventing and treating diabetic complication contains Laminaria japonicaextract or polyphyrin compounds as an active ingredient. The polypyrincompounds are denoted by chemical formula 1 or 2. The Laminaria japonica extract includes crude extract, ethanol, and non-polar solvent soluble extract. A food composition for preventing and treating diabetes complication contains the extract as an active ingredient.