Abstract:
PURPOSE: A fuel cell is provided to improve fuel supply efficiency by using an adhesive consisting of a mixture of Ni/YSZ and metal in order to support a unit cell by a metal plate without using an adhesive like slurry. CONSTITUTION: A fuel cell using a bonding layer of functionally gradient material comprises a metallic plate(10), a fuel electrode(31), and a bonding layer(20) bonding the metallic plate and the fuel electrode. The bonding layer is a functionally gradient material consisting of a metal material, and a material forming the fuel electrode. The functionally gradient material has higher content of the metal material toward the metal plate. The metal material comprises Fe. The material forming the fuel electrode is Ni/YSZ. Content of the metal material in the functionally gradient material is reduced from the metal plate toward the fuel electrode from 80 weight% to 20 weight%.
Abstract:
PURPOSE: Conjugates comprising oligonucleotide and hydrophilic polymers for gene transfer, hybrid polyion complex micelles and preparation methods thereof are provided, thereby effectively transferring the oligonucleotide within a cell, and exhibiting the activity of antisense oligonucleotide at relatively low concentration. CONSTITUTION: Conjugates comprising oligonucleotide and hydrophilic polymers for gene transfer are provided, wherein the terminal group of the oligonucleotide is covalently coupled to the hydrophilic polymers; the hydrophilic polymer is selected from nonionic polymers having the molecular weight of 500; the molecular weight of oligonucleotide is selected from between 1,000 to 50,000; the hydrophilic polymer is selected from polyethyleneglycol, polyvinylpyrrolidone, and polyoxazoline; the bond between oligonucleotide and hydrophilic polymer is selected from amide bond, carbamate bond, hydrazone bond, phosphoroamidate bond, acetal bond, disulfide bond, ester bond, and anhydride bond; and the antisense oligonucleotide comprises a portion or the total of c-myc, c-myb, c-fos, or c-jun.
Abstract:
PURPOSE: A process for preparing mixed micelles containing oligonucleotide and aliphatic polyester-based polymers is provided. Whereby, the mixed micelles can effectively deliver the oligonucleotide, which is used in gene therapy, into cells and the release amount thereof can be easily controlled. CONSTITUTION: An aliphatic polyester-based biodegradable polymer and an activating agent react. The reaction product is dried, mixed with oligonucleotide containing an amine group at the 5'-terminus in a mole ratio of 2:1 to 1:2 and then reacts in an organic solvent to produce a conjugate. The conjugate is dispersed in distilled water to produce a micelle. The aliphatic polyester-based biodegradable polymer is polylactic acid, polyglycolic acid, poly(D,L-lactic acid-co-glycolic acid), polycaprolactone, polyvalero-lactone, polyhydroxy butylate, polyhydroxy valerate or a mixture thereof.
Abstract:
본 발명은 밀봉재를 이용하여 단전지를 고정한 연료전지 및 그 고정방법에 관한 것으로서, 보다 구체적으로는 밀봉재가 연료가스의 누출을 방지하는 기능 이외에도 단전지를 고정시키는 기능을 동시에 제공함과 더불어, 밀봉재가 금속판에 접하는 면적을 증대시켜 그 접합 강도를 증대시키는 밀봉재를 이용하여 단전지를 고정한 연료전지 및 그 고정방법에 관한 것이다.
Abstract:
본 발명은 금속 페이스트를 이용한 연료전지 및 그 제조방법에 관한 것으로서, 보다 구체적으로는 연료전지의 금속판과 연료극을 포함하는 단전지를 금속 페이스트를 코팅한 후, 이를 소결시킴으로써 접합하는 연료전지 및 그 제조방법에 관한 것이다. 특히, 금속 페이스트를 금속판에 형성된 유로를 피하여 코팅함으로써, 최종적으로 금속판의 유로와 단전지의 사이에 다른 물질이 존재하지 않게 되는 효과를 제공하는 금속 페이스트 지지형 연료전지 및 그 제조방법에 관한 것이다.
Abstract:
PURPOSE: A fuel cell using metal paste and a method for manufacturing the same are provided to reduce a cost required for manufacturing processes and to improve the supply efficiency of fuel by supporting unit cells using the metal plate. CONSTITUTION: A fuel cell uses a metal plate(10), unit cells(30), and a metal paste layer(20). A fuel channel(11) is formed at the metal plate. The unit cells include fuel electrodes(31). The metal paste layer bonds the metal plate and the unit cells. A method for manufacturing the fuel cell includes the following: The metal paste layer is coated on the surface of the metal plate avoiding the fuel channel. The unit cells are arranged on the upper layer of the metal paste layer. The metal plate and the unit cells are bonded through a high temperature sintering process with respect to the metal paste layer. A space(21) is formed between the fuel channel and the unit cells.