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31.发明公开3-PYRROLIDINYLOXY-3'-PYRIDYL ETHER COMPOUNDS USEFUL FOR CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION 审中-公开3-吡咯烷基-3“吡啶醚化合物适合于控制化学突触传递
公开(公告)号：EP1212319A2
公开(公告)日：2002-06-12
申请号：EP00965070.6
申请日：2000-09-14
Applicant: Abbott Laboratories
Inventor： LIN, Nan-Horng , LI, Yihong , DRIZIN, Irene , KINCAID, John, F. , BASHA, Anwer , DONG, Liming , HAKEEM, Ahmed, A.
IPC: C07D401/12 , C07D401/14 , C07D409/14 , A61K31/4427 , A61P25/00
CPC classification number: C07D401/12 , C07D401/14 , C07D409/14
Abstract: A series of 3-pyrrolidinyloxy-3'-pyridyl ether compounds, a method for selectively controlling neurotransmitter release in mammals using these compounds, and pharmaceutical compositions including these compounds. Preferred compounds are 3-pyrrolidinylmethoxy-3'-(5'-and/or 6'-substituted) pyridyl ethers.
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32.发明授权BENZOPYRANOPYRROLE AND BENZOPYRANOPYRIDINE ALPHA-1 ADRENERGIC COMPOUNDS 失效BENZOPYRANOPYRROLE和BENZOPYRANOPYRIDINE用α-1肾上腺素的影响
公开(公告)号：EP0942911B1
公开(公告)日：2001-10-17
申请号：EP97951555.8
申请日：1997-12-04
Applicant: Abbott Laboratories
Inventor： MEYER, Michael, D. , ALTENBACH, Robert, J. , BASHA, Fatima , CARROLL, William, A. , DRIZIN, Irene , KERWIN, James, F. , WENDT, Michael, D. , HAIGHT, Anthony, R. , ZHANG, Weijiang
IPC: C07D491/04 , A61K31/415
CPC classification number: C07D491/04
Abstract: The present invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are α-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are α-1 antagonist compositions and a method for antagonizing α-1 adrenoreceptors and treating BPH.
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33.发明公开
公开(公告)号：EP1075466A1
公开(公告)日：2001-02-14
申请号：EP00914832.1
申请日：2000-03-06
Applicant: Abbott Laboratories
Inventor： CARROLL, William A. , CHEN, Yiyuan , DRIZIN, Irene , KERWIN, James, F. , MOORE, Jimmie, L.
IPC: C07D211/82 , C07D215/20 , C07D211/90 , A61K31/473
CPC classification number: C07D221/04 , C07C45/298 , C07D221/06 , C07C47/55
Abstract: Compounds of formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
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34.发明公开BICYCLIC SUBSTITUTED HEXAHYDROBENZ(E)ISOINDOLE ALPHA-1- ADRENERGIC ANTAGONISTS 失效双环取代的六氢苯并（E）与α-1肾上腺素能拮抗剂活性的异吲哚
公开(公告)号：EP0805812A1
公开(公告)日：1997-11-12
申请号：EP96903364.0
申请日：1996-01-11
Applicant: Abbott Laboratories
Inventor： MEYER, Michael, D. , ALTENBACH, Robert, J. , BASHA, Fatima, Z. , CARROLL, William, A. , DRIZIN, Irene , KERWIN, James, F., Jr. , LEBOLD, Suzanne, A. , LEE, Edmund, L. , PRATT, John, K. , SIPPY, Kevin, B. , TIETJE, Karin, R. , YAMAMOTO, Diane, M.
IPC: A61K31 , A61P13 , A61P15 , A61P25 , C07D401 , C07D403 , C07D471 , C07D473 , C07D475 , C07D487 , C07D491 , C07D495 , C07D498
CPC classification number: C07D401/06 , C07D403/06 , C07D471/04 , C07D473/04 , C07D475/02 , C07D487/04 , C07D491/04 , C07D495/04
Abstract: The present invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are α-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are α-1 antagonist compositions and a method for antagonizing α-1 receptors and treating BPH.
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