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Patent Agency Ranking
公开(公告)号：WO2007027651A3
公开(公告)日：2007-03-08
申请号：PCT/US2006/033620
申请日：2006-08-25
Applicant: ABBOTT LABORATORIES , PEI, Zhonghua , VON GELDERN, Thomas , MADAR, David, J. , LI, Xiaofeng , BASHA, Fatima , YONG, Hong , LONGENECKER, Kenton, L. , BACKES, Bradley, J. , JUDD, Andrew, S. , MULHERN, Mathew, M. , STEWART, Kent, D.
Inventor： PEI, Zhonghua , VON GELDERN, Thomas , MADAR, David, J. , LI, Xiaofeng , BASHA, Fatima , YONG, Hong , LONGENECKER, Kenton, L. , BACKES, Bradley, J. , JUDD, Andrew, S. , MULHERN, Mathew, M. , STEWART, Kent, D.
IPC: C07C211/40 , C07C211/54 , C07C211/62 , C07D213/38 , C07D213/68 , C07D317/64 , C07D487/04 , A61K31/137
Abstract: The present invention relates to compounds, which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, metabolic syndrome , hyperinsulinemia, obesity, atherosclerosis, various immunomodulatory diseases, and other diseases.
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2.发明申请BENZOPYRANOPYRROLE AND BENZOPYRANOPYRIDINE ALPHA-1 ADRENERGIC COMPOUNDS 审中-公开苯并吡咯啉和苯并吡咯啉ALPHA-1 ADRENERGIC化合物
公开(公告)号：WO1998024791A1
公开(公告)日：1998-06-11
申请号：PCT/US1997022279
申请日：1997-12-04
Applicant: ABBOTT LABORATORIES
Inventor： ABBOTT LABORATORIES , MEYER, Michael, D. , ALTENBACH, Robert, J. , BASHA, Fatima , CARROLL, William, A. , DRIZIN, Irene , KERWIN, James, F. , WENDT, Michael, D. , HAIGHT, Anthony, R. , ZHANG, Weijiang
IPC: C07D491/04
CPC classification number: C07D491/04
Abstract: The present invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are alpha -1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are alpha -1 antagonist compositions and a method for antagonizing alpha -1 adrenoreceptors and treating BPH.
Abstract translation: 本发明涉及式（I）化合物及其药学上可接受的盐，其中W是双环杂环体系。 该化合物是α-1肾上腺素能拮抗剂，可用于治疗BPH; 还公开了α-1拮抗剂组合物和拮抗α-1肾上腺素受体并治疗BPH的方法。
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3.发明公开BENZOPYRANOPYRROLE AND BENZOPYRANOPYRIDINE ALPHA-1 ADRENERGIC COMPOUNDS 失效苯并吡喃吡咯和苯并吡喃吡啶ALPHA-1 ADRENERGIC化合物
公开(公告)号：EP0942911A1
公开(公告)日：1999-09-22
申请号：EP97951555.0
申请日：1997-12-04
Applicant: Abbott Laboratories
Inventor： MEYER, Michael, D. , ALTENBACH, Robert, J. , BASHA, Fatima , CARROLL, William, A. , DRIZIN, Irene , KERWIN, James, F. , WENDT, Michael, D. , HAIGHT, Anthony, R. , ZHANG, Weijiang
CPC classification number: C07D491/04
Abstract: The present invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are α-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are α-1 antagonist compositions and a method for antagonizing α-1 adrenoreceptors and treating BPH.
Abstract translation: 本发明涉及式（I）化合物及其药学上可接受的盐，其中W为双环杂环系统。 这些化合物是α-1肾上腺素能拮抗剂，可用于治疗BPH; 还公开了α-1拮抗剂组合物和用于拮抗α-1肾上腺素受体并治疗BPH的方法。
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4.发明公开PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) 有权药用植物精华素抑制剂抑制剂脯氨酸酯酶IV（DPP-IV）
公开(公告)号：EP1919854A2
公开(公告)日：2008-05-14
申请号：EP06790057.1
申请日：2006-08-25
Applicant: ABBOTT LABORATORIES
Inventor： PEI, Zhonghua , VON GELDERN, Thomas , MADAR, David, J. , LI, Xiaofeng , BASHA, Fatima , YONG, Hong , LONGENECKER, Kenton, L. , BACKES, Bradley, J. , JUDD, Andrew, S. , MULHERN, Mathew, M. , STEWART, Kent, D.
IPC: C07C211/40 , C07C211/54 , C07C211/62 , C07D213/38 , C07D213/68 , C07D317/64 , C07D487/04 , A61K31/137
CPC classification number: C07C211/48 , C07C211/40 , C07C217/52 , C07C217/54 , C07C217/74 , C07C217/84 , C07C217/86 , C07C225/22 , C07C229/42 , C07C229/48 , C07C229/60 , C07C233/43 , C07C233/78 , C07C235/46 , C07C237/24 , C07C237/30 , C07C237/42 , C07C255/54 , C07C255/58 , C07C311/22 , C07C311/36 , C07C317/22 , C07C317/36 , C07C2601/14 , C07C2601/16 , C07D207/16 , C07D209/08 , C07D209/48 , C07D211/46 , C07D211/60 , C07D211/62 , C07D213/30 , C07D213/38 , C07D213/64 , C07D213/68 , C07D213/74 , C07D213/82 , C07D217/04 , C07D263/56 , C07D263/60 , C07D277/04 , C07D277/64 , C07D295/135 , C07D295/185 , C07D295/205 , C07D317/66 , C07D319/18 , C07D333/34 , C07D333/38 , C07D409/04 , C07D487/04 , C07D491/048 , C07D495/04 , C07D498/04 , C07D513/04
Abstract: The present invention relates to compounds, which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, metabolic syndrome , hyperinsulinemia, obesity, atherosclerosis, various immunomodulatory diseases, and other diseases.
Abstract translation: 本发明涉及抑制二肽基肽酶IV（DPP-IV）的化合物，其可用于预防或治疗糖尿病，特别是II型糖尿病，以及高血糖症，代谢综合征，高胰岛素血症，肥胖症，动脉粥样硬化，各种免疫调节疾病， 和其他疾病。
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5.发明授权BENZOPYRANOPYRROLE AND BENZOPYRANOPYRIDINE ALPHA-1 ADRENERGIC COMPOUNDS 失效BENZOPYRANOPYRROLE和BENZOPYRANOPYRIDINE用α-1肾上腺素的影响
公开(公告)号：EP0942911B1
公开(公告)日：2001-10-17
申请号：EP97951555.8
申请日：1997-12-04
Applicant: Abbott Laboratories
Inventor： MEYER, Michael, D. , ALTENBACH, Robert, J. , BASHA, Fatima , CARROLL, William, A. , DRIZIN, Irene , KERWIN, James, F. , WENDT, Michael, D. , HAIGHT, Anthony, R. , ZHANG, Weijiang
IPC: C07D491/04 , A61K31/415
CPC classification number: C07D491/04
Abstract: The present invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are α-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are α-1 antagonist compositions and a method for antagonizing α-1 adrenoreceptors and treating BPH.
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