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公开(公告)号：DE60306699D1
公开(公告)日：2006-08-24
申请号：DE60306699
申请日：2003-02-28
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI , SAITO TAKAYOSHI
Abstract: In an improvement of a nozzle tip for a pipetting apparatus which is adapted to be removably attached to a nozzle base of the pipetting apparatus, the nozzle tip includes a head portion having an opening adapted to fit onto the nozzle base, a cylindrical portion extending downward from the head portion. a tip portion provided on the lower side of the cylindrical portion and having a tip opening for aspirating and dispensing a liquid, the tip portion having a diameter smaller than the diameter of the cylindrical portion, and a step portion formed between the cylindrical portion and the tip portion. A plurality of fins are integrally formed from the lower end portion of the cylindrical portion to the peripheral surface of the tip portion through the step portion with the same spacing in a circumferential direction for making the insertion of the nozzle tip into an upper opening of a target container smoothly and for structurally reinforcing the step portion.
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公开(公告)号：DE60306699T2
公开(公告)日：2007-08-02
申请号：DE60306699
申请日：2003-02-28
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI , SAITO TAKAYOSHI
Abstract: In an improvement of a nozzle tip for a pipetting apparatus which is adapted to be removably attached to a nozzle base of the pipetting apparatus, the nozzle tip includes a head portion having an opening adapted to fit onto the nozzle base, a cylindrical portion extending downward from the head portion. a tip portion provided on the lower side of the cylindrical portion and having a tip opening for aspirating and dispensing a liquid, the tip portion having a diameter smaller than the diameter of the cylindrical portion, and a step portion formed between the cylindrical portion and the tip portion. A plurality of fins are integrally formed from the lower end portion of the cylindrical portion to the peripheral surface of the tip portion through the step portion with the same spacing in a circumferential direction for making the insertion of the nozzle tip into an upper opening of a target container smoothly and for structurally reinforcing the step portion.
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公开(公告)号：AU4982093A
公开(公告)日：1995-03-22
申请号：AU4982093
申请日：1993-08-31
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI , KATO YUKO , KATAGI HITOMI , KAWANABE JUNICHI
Abstract: PCT No. PCT/JP93/01227 Sec. 371 Date May 15, 1995 Sec. 102(e) Date May 15, 1995 PCT Filed Aug. 31, 1993 PCT Pub. No. WO95/06878 PCT Pub. Date Mar. 9, 1995A pipetting apparatus is provided with clot detection. The pipetting apparatus comprises a nozzle for aspirating a sample. A pressure sensor is connected with the nozzle for measuring pressure in said nozzle. A plurality of pressure difference calculating circuits are operatively connected with the pressure sensor, each for inputting an output of said pressure sensor and obtaining a pressure difference at a different pressure calculation period, respectively. A plurality of discriminating circuits each having a different discrimination threshold value determined according to each of the pressure calculation periods are provided. An alarm circuit is included for outputting a clot detection alarm signal when at least one of said discriminating circuits discriminates that the obtained pressure difference exceeds the discrimination threshold value.
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公开(公告)号：AU3171993A
公开(公告)日：1993-10-05
申请号：AU3171992
申请日：1992-12-22
Applicant: ALOKA CO LTD
Inventor： KAWANABE JUNICHI , TAKEDA MASAAKI , KATAGI HITOMI , KATO YUKO , PELLETIER BRENT ALLEN
IPC: G01N35/06
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公开(公告)号：EP0606480A4
公开(公告)日：1996-08-07
申请号：EP92921041
申请日：1992-10-02
Applicant: ALOKA KABUSHIKI KAISHA , ABBOTT LAB
Inventor： KAWANABE JUNICHI , TAKEDA MASAAKI , KATAGI HITOMI , KATO YUKO , BIELARCZYK GREGORY A , MAGEE ROSIE L
CPC classification number: G01N35/1016 , G01N33/491 , G01N2035/1018 , G01N2035/1025 , G01N2035/103
Abstract: This invention is directed to suck as quickly as possible an erythrocyte component as a highly viscous liquid when a blood plasma component and the erythrocyte component are pipetted from a blood sample in which the blood plasma component and the erythrocyte component are separated into upper and lower fractions by centrifugal separation. A nozzle portion (32) consists of a nozzle base (35) and a disposable chip (36) and is transferred vertically and horizontally by an XYZ robot (34). Pipetting of the blood plasma component in the blood sample place into a test tube (62) by the nozzle portion (32) is first carried out and after the inner wall of the disposable chip (36) is coated by the blood plasma, pipetting of the erythrocyte component is then carried out.
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Patent Agency Ranking
公开(公告)号：CA2120521A1
公开(公告)日：1993-04-15
申请号：CA2120521
申请日：1992-10-02
Applicant: ALOKA KABUSHIKI KAISHA , ABBOTT LAB
Inventor： KAWANABE JUNICHI , TAKEDA MASAAKI , KATAGI HITOMI , KATO YUKO , BIELARCZYK GREGORY A , MAGEE ROSIE L
Abstract: ¢ ! ¢Object! In pipetting a blood plasma component and a red blood cell component separated vertically in a blood sample by a centrifugation, the ret blood cell component having a high viscosity is aspirated as quickly as possible. ¢Construction! A nozzle 32 is composed of a nozzle base 35 and a disposable tip, 36, and is transferred upwardly and downwardly and to the right and left by an XYZ robot 34. At first the blood plasma component in the blood sample put in a test tube 62 is pipetted by a nozzle 32, and then an inner wall of the disposable tip 36 is coated with the blood plasma component, and thereafter the red blood component is pipetted.
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公开(公告)号：CA2221732A1
公开(公告)日：1996-12-19
申请号：CA2221732
申请日：1996-05-13
Applicant: ABBOTT LAB
Inventor： PELLETIER BRENT ALLEN , KATO YUKO , TAKEDA MASAAKI
Abstract: Embodiments described herein provide a pipetting apparatus with leak detecti on and a method for detecting a leak. In one embodiment, an automatic pipetting apparatus comprises a nozzle having a lower end portion through which a flui d sample is aspirated and dispensed by changes in air pressure supplied to the nozzle. A piping system operatively connects the nozzle to a pump for supplying the air pressure to the nozzle. A pressure sensor is operatively connected with the piping system for measuring internal pressure in the pipi ng system. Means is operatively connected with the nozzle for three-dimensional ly moving the nozzle between an aspirating position of the fluid sample and a dispensing position. Leak detecting means is operatively connected with the pressure sensor for detecting a leak in the piping system based upon a measured result obtained by measuring the internal pressure in the piping system with the pressure sensor while the nozzle, which has aspirated a predetermined volume of the fluid sample, is being moved between the aspirating position and the dispensing position by the moving means.
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公开(公告)号：JP2004053497A
公开(公告)日：2004-02-19
申请号：JP2002213391
申请日：2002-07-23
Applicant: Aloka Co Ltd , アロカ株式会社
Inventor： TAKEDA MASAAKI
Abstract: PROBLEM TO BE SOLVED: To solve the problem that the execution of time management on each specimen until pretreatments considerably burdens an operator and that the inappropriate execution of time management may affect the results of analysis on specimens and hinder speedy tests.
SOLUTION: The operator inputs the time of specimen collection on each specimen at which each specimen is collected to a specimen information storage part 50. The specimen information storage part 50 stores coagulation time suitable for centrifugation on each specimen. When a specimen container 2 is inserted in a specimen pretreating device 30, a specimen container label 4 pasted to the specimen container 2 is read to distinguish the specimen. The time of specimen collection and the coagulation time on the distinguished specimen are acquired by referring to the specimen information storage part 50. A pretreatment control part 60 determines whether it is appropriate to centrifuge the specimen or not on the basis of whether the coagulation time has passed or not since the time of specimen collection. The specimen container 2 is temporarily transferred to a standby area 120 in the case that a sufficient coagulation time for centrifugation has not passed.
COPYRIGHT: (C)2004,JPO-
公开(公告)号：JP2003098184A
公开(公告)日：2003-04-03
申请号：JP2001293961
申请日：2001-09-26
Applicant: ALOKA CO LTD
Inventor： SAITO TAKAYOSHI , TAKEDA MASAAKI
Abstract: PROBLEM TO BE SOLVED: To provide a dispensing nozzle for mounting a nozzle chip with relatively small force and high positioning accuracy, a nozzle chip, and a dispensing apparatus. SOLUTION: The dispensing nozzle 12 comprises a nozzle base section 18, and a nozzle chip 20. A retaining surface 32 for retaining the nozzle chip 20 is provided on the side of a tip section 24 of the nozzle base section 18. Additionally, a taper surface 29 for positioning the nozzle chip 20 is provided at the base edge section 24 of the nozzle base section 18. A taper surface 26 is also provided at the peripheral end section of an opening at the base edge side of the nozzle chip 20. By bringing the taper surface 29 into contact with the taper surface 26, the nozzle chip 20 is positioned to the nozzle base section 18. Since the area of the retaining surface 32 is relatively small at the nozzle base section 18, press fit force can be reduced relatively when fitting the nozzle chip 20 to the nozzle base section 18.
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公开(公告)号：JPH1194844A
公开(公告)日：1999-04-09
申请号：JP25955897
申请日：1997-09-25
Applicant: ALOKA CO LTD
Inventor： TAKEDA MASAAKI , MATSUDA TORU
IPC: G01N35/10
Abstract: PROBLEM TO BE SOLVED: To prevent splashing of a delivered residual liquid while improving a treating speed in the replacing of a nozzle chip of the analyzer for having an automatically dispensing function. SOLUTION: A pressure sensor 70 is provided to measure a pressure in a nozzle base part 52 into which is press-fitted a nozzle chip 54. A control part 80 controls the operation of pulling the nozzle chip 54 out of the nozzle base part 52, based on a pressure value to be outputted from the pressure sensor 70. The control part 80 detects that the pressure value begins to lower and switches the pulling out operation from a high speed to a low speed, which can prevent a sharp drop in the pressure within the nozzle chip 54 to block the fouling of the nozzle base part 52 as caused by the splashing of a delivered residual liquid. When detecting that the pressure value reaches an atmospheric pressure, the control part 80 judges that there is no risk of splashing to accelerate the pulling out operation. This allows a low speed operation only during a period when the risk of splashing remains possible and a high speed operation during the other periods thereby shortening the treating time.
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