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    SYSTEM FOR MONITORING AN INDUSTRIAL PROCESS AND DETERMINING SENSOR STATUS
    31.
    发明申请
    SYSTEM FOR MONITORING AN INDUSTRIAL PROCESS AND DETERMINING SENSOR STATUS 审中-公开
    监测工业过程和确定传感器状态的系统

    公开(公告)号：WO1994028557A1

    公开(公告)日：1994-12-08

    申请号：PCT/US1994006086

    申请日：1994-05-27

    Applicant: ARCH DEVELOPMENT CORPORATION

    Inventor： ARCH DEVELOPMENT CORPORATION ,  GROSS, Kenneth, C. ,  HOYER, Kristin, K. ,  HUMENIK, Keith, E.

    IPC: G21C07/36

    CPC classification number: G21C17/00 ,  G05B9/03 ,  Y10S706/914

    Abstract: A method and system for monitoring an industrial process and a sensor. The method and system include generating a first and second signal characteristic of an industrial process variable. One of the signals can be an artificial signal generated by an auto regressive moving average technique. After obtaining two signals associated with one physical variable, a difference function is obtained by determining the arithmetic difference between the two pairs of signals over time. A frequency domain transformation is made of the difference function to obtain Fourier modes describing a composite function. A residual function is obtained by subtracting the composite function from the difference function and the residual function (free of nonwhite noise) is analysed by a statistical probability ratio test.

    Abstract translation: 一种用于监测工业过程和传感器的方法和系统。 该方法和系统包括产生工业过程变量的第一和第二信号特征。 其中一个信号可以是通过自回归移动平均技术产生的人造信号。 在获得与一个物理变量相关联的两个信号之后，通过确定两对信号随时间的算术差异来获得差分函数。 由差分函数进行频域变换，以获得描述复合函数的傅里叶模式。 通过从差分函数中减去复合函数获得剩余函数，并通过统计概率比检验来分析剩余函数（无非噪声）。

    METHODS AND MATERIALS RELATING TO THE FUNCTIONAL DOMAINS OF DNA BINDING PROTEINS
    32.
    发明申请
    METHODS AND MATERIALS RELATING TO THE FUNCTIONAL DOMAINS OF DNA BINDING PROTEINS 审中-公开
    与DNA结合蛋白功能领域相关的方法和材料

    公开(公告)号：WO1994023030A2

    公开(公告)日：1994-10-13

    申请号：PCT/US1994002611

    申请日：1994-03-10

    Applicant: ARCH DEVELOPMENT CORPORATION

    Inventor： ARCH DEVELOPMENT CORPORATION ,  SUKHATME, Vikas, P.

    IPC: C12N15/12

    CPC classification number: C07K14/475 ,  A61K38/00 ,  C07K14/4702 ,  C07K16/18 ,  C07K2319/00 ,  C07K2319/09 ,  C07K2319/61 ,  C07K2319/71 ,  C07K2319/75 ,  C07K2319/81

    Abstract: Disclosed are DNA sequences encoding novel DNA binding proteins implicated in regulation of early stages of cell growth. Illustratively provided are human and mouse origin DNA sequences encoding early growth regularoty ("Egr") proteins which include "zinc finger" regions of the type involved in DNA binding. Also disclosed is a detailed analysis of the structure and function of the early growth regulatory protein, Egr-1, delineating independent and modular activation, repression, DNA-binding, and nuclear localization activities. Also disclosed are immunological methods and materials for detection of Egr proteins and hybridization methods and materials for detection and quantification of Egr protein related nucleic acids.

    Abstract translation: 公开了编码涉及细胞生长早期阶段调节的新型DNA结合蛋白的DNA序列。 说明性地提供了编码早期生长调节蛋白（“Egr”）蛋白质的人和小鼠来源的DNA序列，其包括涉及DNA结合的类型的“锌指”区域。 还公开了对早期生长调节蛋白Egr-1的结构和功能的详细分析，描绘独立和模块化激活，抑制，DNA结合和核定位活动。 还公开了用于检测Egr蛋白的免疫学方法和材料以及用于检测和定量Egr蛋白相关核酸的杂交方法和材料。

    CYANOBACTERIAL AND PLANT ACETYL-CoA CARBOXYLASE
    33.
    发明申请
    CYANOBACTERIAL AND PLANT ACETYL-CoA CARBOXYLASE 审中-公开
    CYANOBACTERIAL和植物乙酰辅酶A羧酸酶

    公开(公告)号：WO1994008016A1

    公开(公告)日：1994-04-14

    申请号：PCT/US1993009340

    申请日：1993-09-30

    Applicant: ARCH DEVELOPMENT CORPORATION

    Inventor： ARCH DEVELOPMENT CORPORATION ,  HASELKORN, Robert ,  GORNICKI, Piotr

    IPC: C12N15/52

    CPC classification number: C12N9/93 ,  C12N15/8241 ,  C12N15/8247 ,  C12N15/8274

    Abstract: The present invention provides isolated and purified polynucleotides that encode plant and cyanobacterial polypeptides that participate in the carboxylation of acetyl-CoA. Isolated cyanobacterial and plant polypeptides that catalyze acetyl-CoA carboxylation are also provided. Processes for altering acetyl-CoA carboxylation, increasing herbicide resistance of plants and identifying herbicide resistant variants of acetyl-CoA carboxylase are also provided.

    Abstract translation: 本发明提供编码参与乙酰辅酶A羧化的植物和蓝细菌多肽的分离和纯化的多核苷酸。 还提供了分离的蓝细菌和催化乙酰辅酶A羧化的植物多肽。 还提供了改变乙酰辅酶A羧化作用，增加植物的除草剂抗性和鉴定乙酰辅酶A羧化酶的除草剂抗性变体的方法。

    PAPILLOMAVIRUS: BIOSYNTHETIC PROCESS AND ASSAYS
    34.
    发明申请
    PAPILLOMAVIRUS: BIOSYNTHETIC PROCESS AND ASSAYS 审中-公开
    PAPILLOMAVIRUS：生物工艺和测定

    公开(公告)号：WO1994004662A1

    公开(公告)日：1994-03-03

    申请号：PCT/US1993007171

    申请日：1993-07-30

    Applicant: ARCH DEVELOPMENT CORPORATION

    Inventor： ARCH DEVELOPMENT CORPORATION ,  MEYERS, Craig, M. ,  LAIMINS, Laimonis, A.

    IPC: C12N07/02

    CPC classification number: C12N7/00 ,  A61K39/00 ,  C12N5/0629 ,  C12N2501/70 ,  C12N2510/02 ,  C12N2710/20051 ,  G01N33/5008 ,  G01N33/56983 ,  G01N2333/025 ,  G01N2500/10

    Abstract: The present invention provides a process of biosynthesizing papillomavirus by inducting complete differentiation of an epithelial cell that contains papillomavirus DNA. Complete differentiation is induced by exposing epithelial cells to a protein kinase C inducer. Assays for screening agents that modify papillomavirus biosynthesis, determining the papillomavirus infectivity of epithelial cells, detecting the presence of anti-papillomavirus antibodies and vaccinating against papillomavirus infection are also provided.

    Abstract translation: 本发明提供了通过诱导包含乳头瘤病毒DNA的上皮细胞的完全分化来生物合成乳头瘤病毒的方法。 通过将上皮细胞暴露于蛋白激酶C诱导物诱导完全分化。 还提供了修饰乳头瘤病毒生物合成的筛选试剂的测定，确定上皮细胞的乳头瘤病毒感染性，检测抗乳头状瘤病毒抗体的存在和针对乳头瘤病毒感染的疫苗。

    SOMATOSTATIN RECEPTORS
    35.
    发明申请
    SOMATOSTATIN RECEPTORS 审中-公开
    SOMATOSTATIN受体

    公开(公告)号：WO1993013130A1

    公开(公告)日：1993-07-08

    申请号：PCT/US1992011327

    申请日：1992-12-30

    Applicant: ARCH DEVELOPMENT CORPORATION

    Inventor： ARCH DEVELOPMENT CORPORATION ,  BELL, Graeme, I. ,  YAMADA, Yuichiro ,  SEINO, Susumu

    IPC: C07K13/00

    CPC classification number: C07K14/723

    Abstract: The invention relates generally to compositions of and methods for obtaining somatostatin receptors. The invention relates as well to the DNA sequences encoding somatostatin receptors, the recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant somatostatin receptor polypeptides. By way of example, the invention discloses th cloning and functional expression of at least three different somatostatin receptors, SSTR1, SSTR2 and SSTR3 from two different mammalian sources. The invention includes as well, methods for using the isolated, recombinant receptor polypeptides in assays designed to select and improve substances capable of interacting with somatostatin receptor polypeptides for use in diagnostic, drug design and therapeutic applications.

    Abstract translation: 本发明一般涉及用于获得生长抑素受体的组合物和方法。 本发明还涉及编码生长抑素受体的DNA序列，携带这些序列的重组载体，包含序列或载体的重组宿主细胞和重组生长抑素受体多肽。 举例来说，本发明公开了来自两种不同哺乳动物来源的至少三种不同生长抑素受体SSTR1，SSTR2和SSTR3的克隆和功能表达。 本发明还包括在测定中使用分离的重组受体多肽的方法，其设计用于选择和改善能够与生长抑素受体多肽相互作用的物质用于诊断，药物设计和治疗应用。

    NUCLEIC ACID ENCODING SODIUM CHANNEL PROTEIN
    38.
    发明申请
    NUCLEIC ACID ENCODING SODIUM CHANNEL PROTEIN 审中-公开
    核酸编码SODIUM通道蛋白

    公开(公告)号：WO1990009391A1

    公开(公告)日：1990-08-23

    申请号：PCT/US1990000768

    申请日：1990-02-09

    Applicant: ARCH DEVELOPMENT CORPORATION

    Inventor： ARCH DEVELOPMENT CORPORATION ,  ROGART, Richard, B.

    IPC: C07H15/12

    CPC classification number: C07K14/705 ,  A61K38/00

    Abstract: The present invention relates generally to sodium channel proteins and more particularly to mammalian cardiac sodium channel proteins, to DNA sequences encoding sodium channel proteins, to the polypeptide products of recombinant expression of these DNA sequences, to peptides whose sequences are based on amino acid sequences deduced from these DNA sequences, to antibodies specific for such proteins and peptides, and to procedures for detection and quantitation of such proteins and nucleic acids related thereto, as well as to procedures relating to the development of anti-arrhythmic and cardiotonic drugs.

    Abstract translation: 本发明一般涉及钠通道蛋白，更具体地涉及哺乳动物心脏钠通道蛋白，编码钠通道蛋白的DNA序列，涉及这些DNA序列的重组表达的多肽产物，其序列基于推导的氨基酸序列 从这些DNA序列到针对这些蛋白质和肽特异性的抗体，以及与这些蛋白质和肽相关的这些蛋白质和核酸的检测和定量的程序，以及与抗心律失常药物和强心药物的发展有关的程序。

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