公开(公告)号：DE4242675A1

公开(公告)日：1994-06-23

申请号：DE4242675

申请日：1992-12-17

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  BEHL BERTHOLD DR ,  HOFMANN HANS PETER DR

IPC: C07D209/42 ,  A61K31/40

公开(公告)号：DE4241562A1

公开(公告)日：1994-06-16

申请号：DE4241562

申请日：1992-12-10

Applicant: BASF AG

Inventor： SCHLECKER RAINER DR ,  TREIBER HANS-JOERG DR ,  BEHL BERTHOLD DR ,  HOFMANN HANS PETER DR

IPC: A61K31/505 ,  A61K31/55 ,  A61P9/10 ,  A61P25/00 ,  A61P25/06 ,  A61P25/08 ,  A61P25/16 ,  A61P25/24 ,  A61P25/28 ,  C07D471/14 ,  C07D487/04 ,  C07D487/14 ,  C07D491/044 ,  C07D491/147 ,  C07D495/14 ,  A61K31/645

Abstract: Triazolopyrimidines of the formula I where A, D and X have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.

公开(公告)号：DE4217952A1

公开(公告)日：1993-12-02

申请号：DE4217952

申请日：1992-05-30

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  BEHL BERTHOLD DR

IPC: A61K31/495 ,  A61K31/498 ,  A61P25/00 ,  A61P25/08 ,  A61P25/20 ,  A61P25/22 ,  A61P25/24 ,  A61P25/26 ,  C07D241/44 ,  C07D241/52 ,  C07D401/04 ,  C07D403/04 ,  C07D487/12 ,  C07D487/14 ,  C07D207/30

Abstract: Quinoxaline-2,3-(1H,4H)diones of the general formula I in which the variables have the following meaning: R is hydrogen; an aliphatic radical having up to 12 C atoms, which can carry one of the following substituents: phenyl, cyclopentyl, cyclohexyl or a group -CO-R , -CO-O-R or -CO-NH-R , where R denotes hydrogen, C1-C4-alkyl, phenyl, benzyl or 1-phenylethyl; a cycloaliphatic radical having up to 12 C atoms, or a phenyl group, where the cyclic groups contained in R can carry up to three of the following substituents: C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, halogen, nitro, cyano, -CO-O-R and -CO-NH-R ; R is a pyrrol-1-yl group which can carry up to two of the following substituents: C1-C4-alkyl, phenyl, phenylsulphonyl, nitro, cyano and one of the groups -CO-O-R , -CO-NH-R , -CH2-O-R , -O-R and -CH=NO-R ; R is identical or different radicals from the following: C1-C4-alkyl, C1-C4-alkoxy, trifluoromethyl, trichloromethyl, trifluoromethoxy, trichloromethoxy, fluorine, chlorine, bromine, iodine, nitro, cyano and one of the groups -CO-O-R and -CO-NH-R and a fused benzene ring; n is 0 to 3. Quinoxaline-2,3-(1H,4H)diones I' in which R has the meaning mentioned. The compounds I and I' are suitable as medicines for human and veterinary medicine.