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公开(公告)号：ZA200108204B
公开(公告)日：2004-05-26
申请号：ZA200108204
申请日：2001-10-05
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , GRANDEL ROLAND , SCHULT SABINE , MUELLER REINHOLD
IPC: C07D235/08 , A61K31/4184 , A61K31/4427 , A61K31/4523 , A61K31/496 , A61K31/551 , A61P3/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P43/00 , C07D235/10 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/08 , C07D403/08 , C07D , A61K , A61P
Abstract: Compounds of the formula I or IIand their tautomeric forms, possible enantiomeric and diastereomeric forms, possible cistrans isomers on the rings in A and prodrugs thereof, pharmaceutical compositions containing these compounds and methods of treating neurodegenerative diseases or neuronal damage with these compounds.
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公开(公告)号：AU764216B2
公开(公告)日：2003-08-14
申请号：AU3034300
申请日：1999-11-23
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOGER THOMAS , SCHULT SABINE , GRANDEL ROLAND , MULLER REINHOLD
IPC: A61K20060101 , A61K31/4184 , A61K31/454 , A61K31/496 , A61P20060101 , A61P3/12 , A61P9/00 , A61P9/10 , A61P13/12 , A61P17/02 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D20060101 , C07D235/30 , C07D401/04 , C07D401/14 , C07D403/04
Abstract: Compounds of the formula Ia or IB where A is a saturated or monounsaturated heterocyclic, 4 - to 8-membered ring which contains one or two nitrogen atoms, and their tautomeric forms, possible enantiomeric and diastereomeric forms, their prodrugs and possible physiologically tolerated salts are useful as inhibitors of the enzyme poly(ADP-ribose)polymerase.
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公开(公告)号：PL351558A1
公开(公告)日：2003-05-05
申请号：PL35155800
申请日：2000-04-27
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , GRANDEL ROLAND , HOLZENKAMP UTA , SCHULT SABINE , MUELLER REINHOLD
IPC: A61K31/415 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/4709 , A61K31/496 , C07D235/20 , A61K31/497 , A61P3/10 , A61P9/00 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D235/18 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D471/04 , A61K31/4164
Abstract: The present invention relates to novel benzimidazoles, their preparation and their use as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30) for producing drugs.
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公开(公告)号：PL351557A1
公开(公告)日：2003-05-05
申请号：PL35155700
申请日：2000-04-11
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , GRANDEL ROLAND , SCHULT SABINE , MUELLER REINHOLD
IPC: C07D235/08 , A61K31/4184 , A61K31/4427 , A61K31/4523 , A61K31/496 , A61K31/551 , A61P3/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P43/00 , C07D235/10 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/08 , C07D403/08 , C07D235/06 , A61K31/4164
Abstract: Compounds of the formula I or IIand their tautomeric forms, possible enantiomeric and diastereomeric forms, possible cistrans isomers on the rings in A and prodrugs thereof, pharmaceutical compositions containing these compounds and methods of treating neurodegenerative diseases or neuronal damage with these compounds.
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公开(公告)号：HRP20010484A2
公开(公告)日：2003-04-30
申请号：HRP20010484
申请日：2001-06-26
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , SCHULT SABINE , GRANDEL ROLAND , MUELLER REINHOLD
IPC: A61K20060101 , A61K31/4184 , A61K31/454 , A61K31/496 , A61P20060101 , A61P3/12 , A61P9/00 , A61P9/10 , A61P13/12 , A61P17/02 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D20060101 , C07D235/30 , C07D401/04 , C07D401/14 , C07D403/04
Abstract: Compounds of the formula Ia or IB where A is a saturated or monounsaturated heterocyclic, 4 - to 8-membered ring which contains one or two nitrogen atoms, and their tautomeric forms, possible enantiomeric and diastereomeric forms, their prodrugs and possible physiologically tolerated salts are useful as inhibitors of the enzyme poly(ADP-ribose)polymerase.
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Patent Agency Ranking
公开(公告)号：HU0200859A2
公开(公告)日：2002-11-28
申请号：HU0200859
申请日：2000-04-11
Applicant: BASF AG
Inventor： GRANDEL ROLAND , HOERGER THOMAS , KOCK MICHAEL , LUBISCH WILFRIED , MUELLER REINHOLD , SCHULT SABINE
IPC: C07D235/08 , A61K31/4184 , A61K31/4427 , A61K31/4523 , A61K31/496 , A61K31/551 , A61P3/10 , A61P9/00 , A61P9/10 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/04 , A61P43/00 , C07D235/10 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/08 , C07D403/08 , C07D235/06
Abstract: Compounds of the formula I or IIand their tautomeric forms, possible enantiomeric and diastereomeric forms, possible cistrans isomers on the rings in A and prodrugs thereof, pharmaceutical compositions containing these compounds and methods of treating neurodegenerative diseases or neuronal damage with these compounds.
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公开(公告)号：CA2408369A1
公开(公告)日：2002-11-07
申请号：CA2408369
申请日：2001-05-09
Applicant: BASF AG
Inventor： KOCK MICHAEL , GRANDEL ROLAND , LUBISCH WILFRIED , HOLZENKAMP UTA , HOGER THOMAS , SCHULT SABINE , MULLER REINHOLD
IPC: A61K31/404 , A61K31/496 , A61P3/10 , A61P7/00 , A61P9/08 , A61P9/10 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07D209/08 , C07D209/12 , C07D209/10 , C07D209/14 , C07D401/04 , C07D403/04 , C07D409/04
Abstract: The invention relates to novel indole derivatives, to the production thereof and to the use thereof as inhibitors of the enzyme poly(ADP ribose)polymeras e or PARP (EC 2.4.2.30) for producing medicaments.
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公开(公告)号：SK15962001A3
公开(公告)日：2002-06-04
申请号：SK15962001
申请日：2000-04-27
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOGER THOMAS , GRANDEL ROLAND , HOLZENKAMP UTA , SCHULT SABINE , MULLER REINHOLD
IPC: A61K31/415 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/4709 , A61K31/496 , A61K31/497 , A61P3/10 , A61P9/00 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/16 , C07D235/20 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D235/18 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D471/04
Abstract: The present invention relates to novel benzimidazoles, their preparation and their use as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30) for producing drugs.
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39.发明专利
公开(公告)号：CZ20012373A3
公开(公告)日：2002-05-15
申请号：CZ20012373
申请日：2000-09-15
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOGER THOMAS , SCHULT SABINE , GRANDEL ROLAND , MULLER REINHOLD
IPC: A61K31/55 , A61P3/10 , A61P9/10 , A61P11/00 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/14 , A61P25/16 , A61P25/28 , A61P29/00 , A61P35/00 , C07D487/06
Abstract: The invention relates to compounds of formula (I) as well as to the tautomeric forms thereof, possible enantiomeric and diastereomeric forms and the prodrugs thereof, the production and use thereof, whereby the values have the meaning as given in the description.
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公开(公告)号：TR200103221T2
公开(公告)日：2002-04-22
申请号：TR200103221
申请日：2000-04-27
Applicant: BASF AG
Inventor： LUBISCH WILFRIED , KOCK MICHAEL , HOEGER THOMAS , GRANDEL ROLAND , HOLZENKAMP UTA , SCHULT SABINE , MUELLER REINHOLD
IPC: A61K31/415 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/437 , A61K31/4439 , C07D235/20 , A61K31/4709 , A61K31/496 , A61K31/497 , A61P3/10 , A61P9/00 , A61P13/12 , A61P19/02 , A61P25/00 , A61P25/08 , A61P25/10 , A61P25/16 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D235/18 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D413/14 , C07D417/04 , C07D471/04
Abstract: The present invention relates to novel benzimidazoles, their preparation and their use as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30) for producing drugs.
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