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    ANTI-STAINING ANTIBACTERIAL DENTIFRICE
    33.
    发明申请
    ANTI-STAINING ANTIBACTERIAL DENTIFRICE 审中-公开
    抗生素抗菌素

    公开(公告)号：WO2005117821A1

    公开(公告)日：2005-12-15

    申请号：PCT/US2005/019415

    申请日：2005-06-02

    Applicant: COLGATE-PALMOLIVE COMPANY ,  MILANOVICH, Nebojsa ,  GAFFAR, Abdul ,  PRENCIPE, Michael ,  BOYD, Thomas

    Inventor： MILANOVICH, Nebojsa ,  GAFFAR, Abdul ,  PRENCIPE, Michael ,  BOYD, Thomas

    IPC: A61K7/16

    CPC classification number: A61K8/33 ,  A61K8/81 ,  A61K8/8164 ,  A61K2800/52 ,  A61Q11/00

    Abstract: An anti-staining, antibacterial dentifrice comprises an anti-staining effective amount of an orally acceptable polymer or copolymer that comprises a plurality of monomeric groups of formula (I) wherein (a) one of A and A' is hydrogen and the other is a moiety (X) n (R) m , (b) n in individual such moieties is independently 0 or 1, (c) linking groups X if present independently comprise an oxygen, sulfur, nitrogen, phosphorus or silicon atom, (d) where n is 0, m is 1, and where n is 1, m is independently an integer from 1 to 3 as determined by X, (e) terminal groups R are independently hydrogen or C 1-18 organic radicals, and (f) M and M' are independently selected from hydrogen, alkali metal and ammonium; said polymer or copolymer having an average molecular weight of at least about 1,000. The dentifrice further comprises an antibacterial effective amount of an orally acceptable halogenated diphenylether antibacterial agent, and an antibacterial enhancing effective amount of an orally acceptable polyvinylmethylether/maleic anhydride copolymer.

    Abstract translation: 抗污染的抗菌洁齿剂包括抗染色有效量的口服可接受的聚合物或共聚物，其包含多个式（I）的单体基团，其中（a）A和A'之一是氢，另一个是 单独这样的部分中的部分（X）n（R）m，（b）n独立地为0或1，（c）连接基团X（如果存在）独立地包含氧，硫，氮，磷或硅原子，（d） n为0，m为1，n为1时，m独立地为1〜3的整数，由X确定，（e）端基R独立地为氢或C 1-18有机基团，（f）M和 M'独立地选自氢，碱金属和铵; 所述聚合物或共聚物的平均分子量至少约为1,000。 洁齿剂还包含抗菌有效量的口服可接受的卤化二苯醚抗菌剂，以及抗菌增强有效量的口服可接受的聚乙烯基甲基醚/马来酸酐共聚物。

    IMPROVED DENTAL WHITENING METHOD
    34.
    发明申请
    IMPROVED DENTAL WHITENING METHOD 审中-公开
    改进的牙齿白化方法

    公开(公告)号：WO2005094768A1

    公开(公告)日：2005-10-13

    申请号：PCT/US2005/010421

    申请日：2005-03-29

    Applicant: COLGATE-PALMOLIVE COMPANY ,  MILANOVICH, Nebojsa ,  CAMERON, Ryan, B. ,  CURTIS, John, P. ,  SUBRAMANYAM, Ravi ,  PRENCIPE, Michael

    Inventor： MILANOVICH, Nebojsa ,  CAMERON, Ryan, B. ,  CURTIS, John, P. ,  SUBRAMANYAM, Ravi ,  PRENCIPE, Michael

    IPC: A61K7/20

    CPC classification number: A61K8/22 ,  A61K2800/88 ,  A61Q11/00

    Abstract: A method for whitening a dental surface comprises nonsimultaneously applying a whitening composition to the surface, the whitening composition comprising at least one orally acceptable peroxy compound, and directing a volume of up to about 2.5 ml of an atomized activating composition on to the surface, wherein the activating composition comprises, in the volume so directed, a peroxy compound activating effective amount of at least one orally acceptable basifying agent, and wherein applying the whitening composition and directing the activating composition are separated by an interval not greater than a peroxy compound activating effective interval. The atomized composition can be directed on to the dental surface before or after application of the whitening composition.

    Abstract translation: 美白牙齿表面的方法包括将美白组合物同时施用于表面，美白组合物包含至少一种口服可接受的过氧化合物，并将一定体积的至多约2.5ml雾化的活化组合物引导至表面，其中 活化组合物包括在如此定向的体积中活化有效量的至少一种口服可接受的碱化剂的过氧化合物，并且其中施用所述增白组合物并引导所述活化组合物以不大于过氧化合物活化的有效间隔 间隔。 雾化组合物可以在施用美白组合物之前或之后被引导到牙齿表面。

    STRIPED DENTIFRICE STABLE TO COLOR BLEEDING
    37.
    发明申请
    STRIPED DENTIFRICE STABLE TO COLOR BLEEDING 审中-公开
    条纹密度稳定

    公开(公告)号：WO1998020849A1

    公开(公告)日：1998-05-22

    申请号：PCT/US1997020382

    申请日：1997-11-12

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： COLGATE-PALMOLIVE COMPANY ,  MILLER, Jeffrey, M. ,  WONG, Michael ,  PRENCIPE, Michael ,  CRAWFORD, Richard, J.

    IPC: A61K07/16

    CPC classification number: A61Q11/00 ,  A61K8/02 ,  A61K8/0237

    Abstract: A striped dentifrice stable color bleeding, wherein at least one component contains a colorant entrained in the matrix of substantially non-fracturable, partially cross-linked melamine-urea-formaldehyde condensation polymer particles, whereby on storage the colorant does not bleed any color into any other dentifrice component. The dentifrice may also contain a formaldehyde scavenger to bind-up any formaldehyde released from the particles.

    Abstract translation: 条纹洁牙剂稳定的颜色渗色，其中至少一种组分含有夹带在基本上不可断裂的部分交联的三聚氰胺 - 脲 - 甲醛缩聚物颗粒的基质中的着色剂，由此在存储时，着色剂不会将任何颜色排放到任何 其他洁齿剂组分。 洁齿剂还可以含有甲醛清除剂以结合从颗粒释放的任何甲醛。

    CODISPENSING OF PHYSICALLY SEGREGATED DENTIFRICES AT CONSISTANT RATIOS
    38.
    发明申请
    CODISPENSING OF PHYSICALLY SEGREGATED DENTIFRICES AT CONSISTANT RATIOS 审中-公开
    按照一致性比例计算物理分离的牙龈卟啉症

    公开(公告)号：WO1997046462A1

    公开(公告)日：1997-12-11

    申请号：PCT/US1997008622

    申请日：1997-05-21

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： COLGATE-PALMOLIVE COMPANY ,  MASTERS, James, G. ,  SULLIVAN, Richard, J. ,  PRENCIPE, Michael ,  CONNAN, A., Patrick

    IPC: B65D35/22

    CPC classification number: B65D81/325 ,  B65D35/22

    Abstract: A method is disclosed for the coextrusion in controlled amounts of at least two dentifrice components stored and physically segregated in a multicompartmented collapsible dispenser provided with a partition which divides the interior volume of the container into separate compartments, the partition being moveable in response to a pressure differential developed thereacross upon the application of Compressive Force to the sidewalls, the individuals dentifrice components containing ingredients which interact when mixed, the dispenser sidewalls being formed of a resilient plastic material which is deflected upon the application thereto of a Deflective Force of about 1.0 or greater pounds, the dentifrice compnents being formulated to be equally extrudible at substantially equivalent compressive forces. When the dispenser sidewalls are compressed, there is extruded a single-banded unmixed multilayer stream of the components containing the reactive ingredients at ratios predetermined to provide optimum levels for interaction between the reacted ingredients when the extruded components are mixed in the oral cavity.

    Abstract translation: 公开了一种用于将受控量的至少两种洁齿剂组分共挤出的方法，所述至少两种洁齿剂组分储存和物理分离在具有将容器的内部容积分成独立隔室的分隔壁的多室压缩分配器中，所述隔板响应于压力而可移动 在压缩力施加到侧壁上时，各种微生物发生变化，所述个体含有混合物相互作用的成分的洁齿剂组分，分配器侧壁由弹性塑料材料形成，弹性塑料材料在应用时偏转约为1.0或更大的防反射力 磅，配方的洁牙剂组分以基本相当的压缩力同等挤出。 当分配器侧壁被压缩时，挤出含有预定比例的反应性成分的组分的单条未混合多层流，以便当将挤出的组分混合在口腔中时，为反应成分之间的相互作用提供最佳水平。

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