公开(公告)号：AT223369T

公开(公告)日：2002-09-15

申请号：AT00101759

申请日：2000-01-28

Applicant: DEGUSSA

Inventor： KRILL STEFFEN DR ,  HUTHMACHER KLAUS DR

IPC: B01J31/26 ,  C07B61/00 ,  C07C67/00 ,  C07C67/08 ,  C07C69/017 ,  C07C69/16

Abstract: Preparation of 2,3,5-trimethylhydroquinone diester derivatives (I) comprises treatment of 2,6,6-trimethyl-cyclohex-2-en-1,4-dione (ketoisophorone) (II) with an acylating agent in the presence of a catalytic amount of a protic acid (i.e. an ortho-boric acid, a boric acid anhydride, a boric acid triester, a hydroxycarboxylic acid or a di- or tri-carboxylic acid optionally containing hydroxy groups). Preparation of trimethylhydroquinone diester derivatives of formula (I) comprises treatment of 2,6,6-trimethyl-cyclohex-2-en-1,4-dione (ketoisophorone) of formula (II) with an acylating agent in the presence of a catalytic amount of a protic acid (i.e. an ortho-boric acid, a boric acid anhydride, a boric acid triester, a hydroxycarboxylic acid or a di- or tri-carboxylic acid optionally containing hydroxy groups. N.B. R and R1 are not defined in the main claim, but in a dependent claim are defined as: R, R1 = optionally substituted 1-20 (especially 2-4)C aliphatic, alicyclic residue or aryl (especially phenyl).

公开(公告)号：DK0832870T3

公开(公告)日：2001-09-24

申请号：DK97115589

申请日：1997-09-09

Applicant: DEGUSSA

Inventor： KRILL STEFFEN DR ,  GIRAY GUENES ,  HUTHMACHER KLAUS DR ,  HUEBNER FRANK DR ,  TANNER HERBERT DR

IPC: B01J23/78 ,  B01J27/138 ,  B01J27/232 ,  C07B61/00 ,  C07C45/67 ,  C07C49/603

Abstract: Production of 3,5,5-trimethylcyclohex-3-en-1-one ( beta -isophorone) (I) comprises liquid phase isomerisation of 3,5,5-trimethylcyclohex-2-en-1-one ( alpha -isophorone) (II) in the presence of a heterogeneous catalyst comprising an oxide or mixed oxide of a Group IIa, VIII, Ib, IIIa and Va element (or a salt of such an oxide which is insoluble under the reaction conditions) and in the absence of an organic base.

公开(公告)号：AT198188T

公开(公告)日：2001-01-15

申请号：AT97115590

申请日：1997-09-09

Applicant: DEGUSSA

Inventor： KRILL STEFFEN DR ,  GIRAY GUENES ,  HUTHMACHER KLAUS DR ,  HUEBNER FRANK DR ,  TANNER HERBERT DR

IPC: B01J23/02 ,  B01J23/75 ,  B01J23/755 ,  C07B61/00 ,  C07C45/67 ,  C07C45/82 ,  C07C45/83 ,  C07C49/603

公开(公告)号：AT196460T

公开(公告)日：2000-10-15

申请号：AT97105752

申请日：1997-04-08

Applicant: DEGUSSA

Inventor： HAHN RAINER DR ,  GORA ULRICH ,  HUTHMACHER KLAUS DR ,  HUEBNER FRANK DR ,  KRILL STEFFEN DR

IPC: B01J31/22 ,  C07B61/00 ,  C07C45/34 ,  C07C49/603

Abstract: Preparation of 3,5,5-trimethylcyclohex-2-en-1,4-dione (I) comprises oxidation of 3,5,5-trimethylcyclohex-3-en-1-one (II) by molecular oxygen in the presence of manganese (salen) or its derivatives as catalyst, an alkylamine and water in an inert solvent in the presence of another catalytic compound X where X = an organic acid with pKa of 2-7, or 1-4C aliphatic alcohol, or phenol, or compounds where an enolic structure is possible, where X is present in a molar ratio of 1:1 to 100:1 with the catalyst and (II) is >15wt.% of the total.

公开(公告)号：AT252092T

公开(公告)日：2003-11-15

申请号：AT01710005

申请日：2001-02-01

Applicant: DEGUSSA

Inventor： HUTHMACHER KLAUS DR ,  KRETZ STEPHAN ,  KRILL STEFFEN DR

IPC: C07D311/72 ,  C07D311/04

Abstract: Process for the production of alpha-tocopherol acetate in a recycling process by condensation of trimethylhydroquinone diesters and isophytol in the presence of a catalyst system consisting of a zinc halide and of an aqueous protonic acid and optionally of an elemental metal in a polar solvent/water mixture which is extractable or miscible with water and subsequent recycling of the catalyst system.

公开(公告)号：DE59807380D1

公开(公告)日：2003-04-10

申请号：DE59807380

申请日：1998-12-04

Applicant: DEGUSSA

Inventor： KRILL STEFFEN DR ,  HUEBNER FRANK DR ,  HAHN RAINER DR ,  WEIGEL HORST ,  HUTHMACHER KLAUS DR

IPC: C07B61/00 ,  C07D311/72

Abstract: Preparation of alpha -tocopherol ester compounds (I) involves reacting a hydroquinone ester (II) with an allyl alcohol derivative (III) in presence of a zinc halide and an acid. Preparation of alpha -tocopherol esters (or derivatives or homologues) of formula (I) involves reacting a hydroquinone mono- (sic) or diester of formula (II) with an allyl alcohol derivative of formula (III) in presence of a zinc halide and a protonic acid at 25-100 degrees C. R1, R2 = optionally unsaturated 1-20C alkyl; R3-R5 = H or 1-3C alkyl; n = 0-5; Q = -C(Me)=CH-CH2L or -C(Me)(L')-CH=CH2; L = OH, halo, acetoxy, MeSO2O, EtSO2O, PhSO2O or toluenesulfonyl; L' = OH, halo or acetoxy.

公开(公告)号：ES2182740T3

公开(公告)日：2003-03-16

申请号：ES00101759

申请日：2000-01-28

Applicant: DEGUSSA

Inventor： KRILL STEFFEN DR ,  HUTHMACHER KLAUS DR

IPC: B01J31/26 ,  C07B61/00 ,  C07C67/00 ,  C07C67/08 ,  C07C69/017 ,  C07C69/16

Abstract: Preparation of 2,3,5-trimethylhydroquinone diester derivatives (I) comprises treatment of 2,6,6-trimethyl-cyclohex-2-en-1,4-dione (ketoisophorone) (II) with an acylating agent in the presence of a catalytic amount of a protic acid (i.e. an ortho-boric acid, a boric acid anhydride, a boric acid triester, a hydroxycarboxylic acid or a di- or tri-carboxylic acid optionally containing hydroxy groups). Preparation of trimethylhydroquinone diester derivatives of formula (I) comprises treatment of 2,6,6-trimethyl-cyclohex-2-en-1,4-dione (ketoisophorone) of formula (II) with an acylating agent in the presence of a catalytic amount of a protic acid (i.e. an ortho-boric acid, a boric acid anhydride, a boric acid triester, a hydroxycarboxylic acid or a di- or tri-carboxylic acid optionally containing hydroxy groups. N.B. R and R1 are not defined in the main claim, but in a dependent claim are defined as: R, R1 = optionally substituted 1-20 (especially 2-4)C aliphatic, alicyclic residue or aryl (especially phenyl).

公开(公告)号：DK1028103T3

公开(公告)日：2003-01-06

申请号：DK00101759

申请日：2000-01-28

Applicant: DEGUSSA

Inventor： KRILL STEFFEN DR ,  HUTHMACHER KLAUS DR

IPC: B01J31/26 ,  C07B61/00 ,  C07C67/00 ,  C07C67/08 ,  C07C69/017 ,  C07C69/16

Abstract: Preparation of 2,3,5-trimethylhydroquinone diester derivatives (I) comprises treatment of 2,6,6-trimethyl-cyclohex-2-en-1,4-dione (ketoisophorone) (II) with an acylating agent in the presence of a catalytic amount of a protic acid (i.e. an ortho-boric acid, a boric acid anhydride, a boric acid triester, a hydroxycarboxylic acid or a di- or tri-carboxylic acid optionally containing hydroxy groups). Preparation of trimethylhydroquinone diester derivatives of formula (I) comprises treatment of 2,6,6-trimethyl-cyclohex-2-en-1,4-dione (ketoisophorone) of formula (II) with an acylating agent in the presence of a catalytic amount of a protic acid (i.e. an ortho-boric acid, a boric acid anhydride, a boric acid triester, a hydroxycarboxylic acid or a di- or tri-carboxylic acid optionally containing hydroxy groups. N.B. R and R1 are not defined in the main claim, but in a dependent claim are defined as: R, R1 = optionally substituted 1-20 (especially 2-4)C aliphatic, alicyclic residue or aryl (especially phenyl).

公开(公告)号：IN188710B

公开(公告)日：2002-10-26

申请号：IN582CA2000

申请日：2000-10-16

Applicant: DEGUSSA

Inventor： WEIGEL HORST ,  KRILL STEFFEN DR ,  HASSELBACH HANS JOACHIM DR ,  HUTHMACHER KLAUS DR

IPC: C07C67/00 ,  C07D311/72

公开(公告)号：AT204251T

公开(公告)日：2001-09-15

申请号：AT97105669

申请日：1997-04-05

Applicant: DEGUSSA

Inventor： HUEBNER FRANK DR ,  KRILL STEFFEN DR ,  DRAPAL BERND ,  SCHMITT HERMANN ,  HUTHMACHER KLAUS DR ,  TANNER HERBERT DR

IPC: B01J31/02 ,  C07B61/00 ,  C07C27/02 ,  C07C37/055 ,  C07C37/07 ,  C07C39/08 ,  C07C67/00 ,  C07C67/08

Abstract: Preparation of 2,3,5-trimethylhydroquinone (I) comprises a) reaction of keto-isophorone with an acylating agent in the presence of catalytic amounts of a protic acid and b) acid hydrolysis of the resulting trimethylhydroquinone ester. The protic acid is oleum, trifluoromethanesulphonic, chlorosulphonic, polyphosphoric acid or a mixture of these.