公开(公告)号：SE7700436L

公开(公告)日：1977-07-18

申请号：SE7700436

Applicant: HOECHST AG

Inventor： LANG H-J ,  MUSCHAWECK R

IPC: A61K31/425 ,  A61K31/426 ,  A61P7/10 ,  C07C67/00 ,  C07C325/00 ,  C07C335/32 ,  C07D207/16 ,  C07D239/10 ,  C07D277/18 ,  C07D295/215 ,  C07D513/04

公开(公告)号：IN141965B

公开(公告)日：1977-05-14

申请号：IN1732CA1975

申请日：1975-09-10

Applicant: HOECHST AG

Inventor： MUSCHAWECK R ,  RUSCHIG H ,  RIPPEL R ,  SCHORR M

IPC: C07D63/12

公开(公告)号：NO763502L

公开(公告)日：1977-04-18

申请号：NO763502

申请日：1976-10-14

Applicant: HOECHST AG

Inventor： LANG H-J ,  MUSCHAWECK R

IPC: A61K31/425 ,  A61K31/426 ,  A61P7/10 ,  C07C311/58 ,  C07C311/59 ,  C07D277/18 ,  C07D295/215 ,  C07D513/04 ,  C07D

Abstract: Diuretically active thiazolidine compounds and methods for making the same are disclosed, said compounds having an alkyl or alkenyl substituent in the 1-position, an imino group in the 2-position, and an hydroxy group and an N-acylated 3'-sulfamoylphenyl substituent in the 4-position, i.e.

公开(公告)号：SE7611504A

公开(公告)日：1977-04-16

申请号：SE7611504

申请日：1976-10-15

Applicant: HOECHST AG

Inventor： LANG H-J ,  MUSCHAWECK R

IPC: A61K31/425 ,  A61K31/426 ,  A61P7/10 ,  C07C311/58 ,  C07C311/59 ,  C07D277/18 ,  C07D295/215 ,  C07D513/04 ,  C07D277/06

CPC classification number: C07D295/215 ,  C07C311/58 ,  C07C311/59 ,  C07C2601/14 ,  C07D277/18 ,  C07D513/04

公开(公告)号：DK464076A

公开(公告)日：1977-04-16

申请号：DK464076

申请日：1976-10-14

Applicant: HOECHST AG

Inventor： LANG H-J ,  MUSCHAWECK R

IPC: A61K31/425 ,  A61K31/426 ,  A61P7/10 ,  C07C311/58 ,  C07C311/59 ,  C07D277/18 ,  C07D295/215 ,  C07D513/04 ,  C07D

Abstract: Diuretically active thiazolidine compounds and methods for making the same are disclosed, said compounds having an alkyl or alkenyl substituent in the 1-position, an imino group in the 2-position, and an hydroxy group and an N-acylated 3'-sulfamoylphenyl substituent in the 4-position, i.e.

公开(公告)号：DK340476A

公开(公告)日：1977-01-30

申请号：DK340476

申请日：1976-07-28

Applicant: HOECHST AG

Inventor： LANG H-J ,  MUSCHAWECK R

IPC: A61K31/425 ,  A61K31/426 ,  A61P7/10 ,  C07D277/18 ,  C07D513/04 ,  C07D

Abstract: The invention relates to thiazolidine derivatives having in 4-position a hydroxy group and a 3'-sulphamyl-phenyl substituent the phenyl ring of which is di-substituted by halogen or methyl, in 2 position an imino group and in 1-position an aliphatic or cycloaliphatic substituent. Said thiazolidines have diuretic activity.

公开(公告)号：ZA7502654B

公开(公告)日：1976-04-28

申请号：ZA7502654

申请日：1975-04-24

Applicant: HOECHST AG

Inventor： MERKEL W ,  MUSCHAWECK R ,  BORMANN D ,  MANIA D

IPC: C07D207/04 ,  A61K20060101 ,  A61K31/40 ,  A61K31/402 ,  A61P7/10 ,  C07D20060101 ,  C07D209/00 ,  C07D209/44 ,  C07D211/30 ,  C07D295/00 ,  C07D295/08 ,  C07D295/116 ,  C07D295/14 ,  C07D295/18 ,  C07D295/192 ,  C07D ,  A61K

公开(公告)号：NO751470L

公开(公告)日：1975-10-28

申请号：NO751470

申请日：1975-04-24

Applicant: HOECHST AG

Inventor： BORMANN D ,  MERKEL W ,  MUSCHAWECK R ,  MANIA D

IPC: C07D207/04 ,  A61K20060101 ,  A61K31/125 ,  A61K31/18 ,  A61K31/33 ,  A61K31/395 ,  A61K31/40 ,  A61K31/402 ,  A61K31/445 ,  A61K31/45 ,  A61K31/635 ,  A61P7/10 ,  C07C20060101 ,  C07D20060101 ,  C07D205/04 ,  C07D207/02 ,  C07D207/06 ,  C07D207/08 ,  C07D207/10 ,  C07D207/18 ,  C07D207/20 ,  C07D207/32 ,  C07D207/327 ,  C07D207/40 ,  C07D207/404 ,  C07D207/44 ,  C07D209/00 ,  C07D209/44 ,  C07D209/48 ,  C07D209/52 ,  C07D209/94 ,  C07D211/04 ,  C07D211/14 ,  C07D211/18 ,  C07D211/30 ,  C07D211/32 ,  C07D211/34 ,  C07D211/38 ,  C07D211/70 ,  C07D211/88 ,  C07D265/32 ,  C07D295/00 ,  C07D295/02 ,  C07D295/04 ,  C07D295/08 ,  C07D295/10 ,  C07D295/116 ,  C07D295/12 ,  C07D295/14 ,  C07D295/155 ,  C07D295/18 ,  C07D295/192 ,  C07D403/10 ,  C07D405/10 ,  C07D407/10 ,  C07D413/10 ,  C07C

公开(公告)号：DK19175A

公开(公告)日：1975-09-15

申请号：DK19175

申请日：1975-01-22

Applicant: HOECHST AG

Inventor： DRUCKREY E ,  KNABE B ,  LANG H-J ,  BABEJ M ,  MUSCHAWECK R

IPC: C07C67/00 ,  C07C209/00 ,  C07C209/08 ,  C07C209/16 ,  C07C209/24 ,  C07C209/50 ,  C07C209/52 ,  C07C209/60 ,  C07C211/35 ,  C07C213/00 ,  C07C217/58 ,  C07D317/58 ,  C07D319/18

Abstract: N-Cycloalkyl-benzylamine derivatives of the formula in which R1 represents hydrogen or lower alkyl of 1 to 4 carbon atoms, R2 represents a cycloalkyl radical of a total of 7 to 12 carbon atoms which may be alkyl-substituted and may contain hydrocarbon bridges of 1 to 3 carbon atoms, R3 represents hydrogen, alkoxy of 1 to 4 carbon atoms, R4 represents hydrogen or alkoxy of 1 to 4 carbon atoms or halogen, and R5 represents alkoxy of 1 to 4 carbon atoms, methylene dioxy, ethylene dioxy, benzyloxy or halogen, and the physiologically tolerated salts thereof are disclosed as having diuretic and saluretic activity.

公开(公告)号：SE7500662L

公开(公告)日：1975-07-24

申请号：SE7500662

申请日：1975-01-22

Applicant: HOECHST AG

Inventor： DRUCKREY E ,  KNABE B ,  LANG H-J ,  BABEJ M ,  MUSCHAWECK R

IPC: C07C67/00 ,  C07C209/00 ,  C07C209/08 ,  C07C209/16 ,  C07C209/24 ,  C07C209/50 ,  C07C209/52 ,  C07C209/60 ,  C07C211/35 ,  C07C213/00 ,  C07C217/58 ,  C07D317/58 ,  C07D319/18 ,  C07C87/40

Abstract: N-Cycloalkyl-benzylamine derivatives of the formula in which R1 represents hydrogen or lower alkyl of 1 to 4 carbon atoms, R2 represents a cycloalkyl radical of a total of 7 to 12 carbon atoms which may be alkyl-substituted and may contain hydrocarbon bridges of 1 to 3 carbon atoms, R3 represents hydrogen, alkoxy of 1 to 4 carbon atoms, R4 represents hydrogen or alkoxy of 1 to 4 carbon atoms or halogen, and R5 represents alkoxy of 1 to 4 carbon atoms, methylene dioxy, ethylene dioxy, benzyloxy or halogen, and the physiologically tolerated salts thereof are disclosed as having diuretic and saluretic activity.