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公开(公告)号:ES2778443T3
公开(公告)日:2020-08-10
申请号:ES17185810
申请日:2017-08-10
Applicant: MEDTRONIC INC
Inventor: GERBER MARTIN T , HOBOT CHRISTOPHER M
Abstract: Un ciclador de diálisis peritoneal (116, 216), que comprende: un tubo combinado de infusión y efluente (128, 228) para administrar y recibir un dializado peritoneal hacia y desde una cavidad peritoneal (10); al menos una bomba (118, 218) colocada en el tubo combinado de infusión y efluente; y al menos un sensor (106a-106h) conectado de manera fluida al tubo combinado de infusión y efluente, en donde el al menos un sensor se selecciona del grupo que consiste en: un sensor de flujo, un electrodo selectivo de iones, un sensor de pH, un sensor de presión, un sensor de índice de refracción, un sensor de conductividad y un sensor de temperatura, caracterizado porque el ciclador de diálisis peritoneal comprende, además: una trayectoria de flujo de muestreo (130, 230) conectada de manera fluida al tubo combinado de infusión y efluente, en la que el al menos un sensor está colocado en la trayectoria de flujo de muestreo; una válvula que conecta el tubo combinado de infusión y efluente a la trayectoria de flujo de muestreo; y al menos una bomba en la trayectoria de flujo de muestreo.
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公开(公告)号:AU2018227226A1
公开(公告)日:2019-04-18
申请号:AU2018227226
申请日:2018-09-10
Applicant: MEDTRONIC INC
Inventor: GERBER MARTIN T , HOBOT CHRISTOPHER M , LURA DAVID B , MANDA VENKATESH , MEYER THOMAS
Abstract: PERITONEAL DIALYSATE PREPARATION AND SENSOR SYSTEM The invention relates to devices, systems, and methods for generating a peritoneal dialysate having specified concentrations of one or more solutes. The devices, systems and methods use conductivity sensors (1107, 1108), flow meters, and composition sensors (1152, 1119) to control addition of osmotic agents and ion concentrates into a peritoneal dialysate generation flow path (1111). 814 815 818 87 8 12 827 11824 820- --- 22 -- 826
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公开(公告)号:DE60333566D1
公开(公告)日:2010-09-09
申请号:DE60333566
申请日:2003-08-13
Applicant: MEDTRONIC INC
Inventor: SPARER RANDALL V , HOBOT CHRISTOPHER M , LYU SUPING
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公开(公告)号:DE60331552D1
公开(公告)日:2010-04-15
申请号:DE60331552
申请日:2003-08-13
Applicant: MEDTRONIC INC
Inventor: LYU SUPING , SPARER RANDALL V , HOBOT CHRISTOPHER M , DANG KIEM
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公开(公告)号:CA2700736A1
公开(公告)日:2009-10-22
申请号:CA2700736
申请日:2009-04-17
Applicant: WARSAW ORTHOPEDIC INC , MEDTRONIC INC
Inventor: KING VANJA MARGARETA , HOBOT CHRISTOPHER M , BIGGS DR DANIELLE , SHAW KATARA , WOHABREBBI AMIRA , MCKAY WILLIAM F , MCDONALD PHILLIP EDWARD
IPC: A61K31/4458 , A61K9/20 , A61K47/34 , A61P29/00
Abstract: The present invention is directed to an implantable drug depot useful for reducing, preventing or treating post-operative pain in a patient in need of such treatment, the implantable drug depot comprising a polymer and a therapeutically effective amount of a local anesthetic or pharmaceutically acceptable salt thereof, wherein the drug depot is implantable at a site beneath the skin to reduce, prevent or treat post-operative pain, and the drug depot is capable of releasing (i) a bolus dose of the local anesthetic or pharmaceutically acceptable salt thereof at a site beneath the skin and (ii) a sustained release dose of an effective amount of the local anesthetic or pharmaceutically acceptable salt thereof over a period of at least 4 days.
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公开(公告)号:CA2700389A1
公开(公告)日:2009-10-22
申请号:CA2700389
申请日:2009-04-17
Applicant: MEDTRONIC INC , WARSAW ORTHOPEDIC INC
Inventor: KING VANJA MARGARETA , HOBOT CHRISTOPHER M , MCKAY WILLIAM F , WOHABREBBI AMIRA , MCDONALD PHILLIP EDWARD , CARTER TROY
IPC: A61K9/00 , A61K9/20 , A61K31/4162 , A61K47/34
Abstract: The present invention is directed to an implantable drug depot useful for reducing, preventing or treating post-operative pain in a patient in need of such treatment, the implantable drug depot comprising a therapeutically effective amount of clonidine or pharmaceutically acceptable salt thereof and a polymer; wherein the depot is implantable at a site beneath the skin to reduce, prevent or treat post-operative pain, and the depot is capable of releasing (i) about 5% to about 45% of the clonidine or pharmaceutically acceptable salt thereof relative to a total amount of the clonidine or pharmaceutically acceptable salt thereof loaded in the drug depot over a first period of up to 48 hours and (ii) about 55% to about 95% of the clonidine or pharmaceutically acceptable salt thereof relative to a total amount of the clonidine or pharmaceutically acceptable salt thereof loaded in the drug depot over a subsequent period of at least 3 days.
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公开(公告)号:AU2009236157A1
公开(公告)日:2009-10-22
申请号:AU2009236157
申请日:2009-04-17
Applicant: WARSAW ORTHOPEDIC INC , MEDTRONIC INC
Inventor: HOBOT CHRISTOPHER M , WOHABREBBI AMIRA , MCDONALD PHILLIP EDWARD , KING VANJA MARGARETA , MCKAY WILLIAM F , CARTER TROY
IPC: A61K9/00 , A61K9/20 , A61K31/4162 , A61K47/34
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公开(公告)号:AU2009236089A1
公开(公告)日:2009-10-22
申请号:AU2009236089
申请日:2009-04-17
Applicant: MEDTRONIC INC , WARSAW ORTHOPEDIC INC
Inventor: KING VANJA MARGARETA , MCKAY WILLIAM F , MCDONALD PHILLIP EDWARD , SHAW KATARA , HOBOT CHRISTOPHER M , BIGGS DANIELLE , WOHABREBBI AMIRA
IPC: A61K31/4458 , A61K9/20 , A61K47/34 , A61P29/00
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公开(公告)号:DE60323243D1
公开(公告)日:2008-10-09
申请号:DE60323243
申请日:2003-09-16
Applicant: MEDTRONIC INC
Inventor: BENZ MICHAEL E , HOBOT CHRISTOPHER M , SPARER RANDALL V
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公开(公告)号:AU2005248772A1
公开(公告)日:2005-12-08
申请号:AU2005248772
申请日:2005-05-11
Applicant: MEDTRONIC INC
Inventor: HOBOT CHRISTOPHER M , MEYER RANDY , SITKO VITALLY G , NIPPOLDT DOUGLAS D , YE QINGSHAN , BONNEMA KELVIN , RAMAMURTHY NARAYANAN , QIN WEI
IPC: G01N27/333 , G01N33/487 , G01N33/86
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