公开(公告)号：AT352329T

公开(公告)日：2007-02-15

申请号：AT03709356

申请日：2003-02-07

Applicant: MEDTRONIC INC

Inventor： BENZ MICHAEL E ,  ALKATOUT JULIE A ,  LYU SUPING

IPC: A61L27/00 ,  A61F2/06 ,  A61F2/16 ,  A61F2/24 ,  A61F2/84 ,  A61L29/00 ,  A61L29/08 ,  A61L29/14 ,  A61L31/00 ,  A61L33/00 ,  A61M25/00 ,  A61M25/01 ,  C08F8/00 ,  C08F293/00 ,  C08G18/10 ,  C08G18/42 ,  C08G18/48 ,  C08G18/50 ,  C08G18/62 ,  C08G18/78 ,  C08G18/79 ,  C08G81/02 ,  C08L53/00 ,  C09D153/00 ,  C09D175/04

Abstract: A n B block copolymers, wherein n is at least two, that include A blocks with poly(vinyl pyrrolidone) units and B blocks with urethane groups, urea groups, imide groups, amide groups, ether groups, ester groups, or combinations thereof, as well as medical devices and methods.

公开(公告)号：CA2467341A1

公开(公告)日：2003-05-22

申请号：CA2467341

申请日：2002-11-13

Applicant: MEDTRONIC INC

Inventor： SCHWENDEMAN JOHN E ,  DIDOMENICO EDWARD ,  BENZ MICHAEL E ,  HOBOT CHRISTOPHER M ,  WAGENER KENNETH B

IPC: A61L27/18 ,  C08F236/20 ,  C08G18/62 ,  A61L29/00

Abstract: Compounds that include diorgano groups having quaternary carbons and optionally urethane groups, urea groups, or combinations thereof (i.e., polyyurethanes, polyureas, or polyurethane-ureas), as well as materials and methods for making such compounds.

公开(公告)号：AU2009322637A1

公开(公告)日：2011-06-30

申请号：AU2009322637

申请日：2009-11-30

Applicant: MEDTRONIC INC

Inventor： BENZ MICHAEL E ,  HOBOT CHRISTOPHER M ,  EDWARD MCDONALD PHILLIP ,  LUO LIAN L ,  JOHN KRAMER

IPC: A61K9/22 ,  A61K47/34

Abstract: Flowable pharmaceutical depots are described. The flowable pharmaceutical depot includes a polyester, such as a polylactic acid or a poly(trimethylene carbonate) endcapped with a primary alcohol and a pain relieving therapeutic agent, such as a post operative pain relieving therapeutic agent. Method of making and using the same are also described.

公开(公告)号：CA2745414A1

公开(公告)日：2010-06-10

申请号：CA2745414

申请日：2009-11-30

Applicant: MEDTRONIC INC

Inventor： BENZ MICHAEL E ,  HOBOT CHRISTOPHER M ,  MCDONALD PHILLIP EDWARD ,  LUO LIAN L ,  KRAMER JOHN

IPC: A61K9/22 ,  A61K47/34

Abstract: Flowable pharmaceutical depots are described. The flowable pharmaceutical depot includes a polyester, such as a polylactic acid or a poly(trimethylene carbonate) endcapped with a primary alcohol and a pain relieving therapeutic agent, such as a post operative pain relieving therapeutic agent. Method of making and using the same are also described.

公开(公告)号：AU2003270704A1

公开(公告)日：2004-04-08

申请号：AU2003270704

申请日：2003-09-16

Applicant: MEDTRONIC INC

Inventor： SPARER RANDALL V ,  BENZ MICHAEL E ,  HOBOT CHRISTOPHER M ,  BONNEMA KELVIN

IPC: A61L27/00 ,  A61L31/00 ,  A61M1/10 ,  C08G18/10 ,  C08G18/38 ,  C08G18/64 ,  C08G77/00 ,  C08G77/60 ,  C08G85/00

Abstract: Polymers that include silane-containing groups in soft segments, and optionally urethane groups, as well as medical devices and methods for making such compounds.

公开(公告)号：CA2499344A1

公开(公告)日：2004-04-01

申请号：CA2499344

申请日：2003-09-16

Applicant: MEDTRONIC INC

Inventor： TAPSAK MARK A ,  PEARSON DAVID A ,  SPARER RANDALL A ,  MILLER DAVID L ,  DIDOMENICO EDWARD ,  HOBOT CHRISTOPHER M ,  BENZ MICHAEL E

IPC: A61L27/18 ,  C08G18/61 ,  C08G77/50 ,  A61L31/00

Abstract: Compounds that include silicon-containing groups, and optionally urethane groups, urea groups, or combinations thereof (i.e., polyurethanes, polyureas , or polyurethane-ureas), as well as materials and methods for making such compounds.

公开(公告)号：AU2002359388A1

公开(公告)日：2003-05-26

申请号：AU2002359388

申请日：2002-11-13

Applicant: MEDTRONIC INC

Inventor： SCHWENDEMAN JOHN E ,  DIDOMENICO EDWARD ,  WAGENER KENNETH B ,  HOBOT CHRISTOPHER M ,  BENZ MICHAEL E

IPC: A61L27/18 ,  C08F236/20 ,  C08G18/62 ,  A61L29/00

公开(公告)号：CA2525631C

公开(公告)日：2012-12-18

申请号：CA2525631

申请日：2004-05-10

Applicant: MEDTRONIC INC

Inventor： BENZ MICHAEL E

IPC: A61L27/18 ,  A61K47/48 ,  A61L27/36 ,  A61L27/54 ,  A61L29/06 ,  A61L29/16 ,  A61L31/06 ,  A61L31/16

Abstract: The present invention provides curable materials, medical devices incorporating such materials, wherein the curable materials are capable of releasing hydrolyzable leaving agents upon hydrolysis that can form agents (e.g., pharmaceutically active agents), and methods of making and using such materials and devices.

公开(公告)号：DE60323243D1

公开(公告)日：2008-10-09

申请号：DE60323243

申请日：2003-09-16

Applicant: MEDTRONIC INC

Inventor： BENZ MICHAEL E ,  HOBOT CHRISTOPHER M ,  SPARER RANDALL V

IPC: A61L27/00 ,  C08G18/61 ,  A61L29/00 ,  A61M1/10 ,  A61N1/05 ,  C08G18/62

公开(公告)号：CA2525631A1

公开(公告)日：2004-11-25

申请号：CA2525631

申请日：2004-05-10

Applicant: MEDTRONIC INC

Inventor： BENZ MICHAEL E

IPC: A61L27/18 ,  A61K47/48 ,  A61L27/36 ,  A61L27/54 ,  A61L29/06 ,  A61L29/16 ,  A61L31/06 ,  A61L31/16

Abstract: The present invention provides curable materials, medical devices incorporating such materials, wherein the curable materials are capable of releasing hydrolyzable leaving agents upon hydrolysis that can form agents (e.g., pharmaceutically active agents), and methods of making and using such materials and devices.