公开(公告)号：WO2004052454B1

公开(公告)日：2004-08-19

申请号：PCT/US0338928

申请日：2003-12-09

Applicant: MEDTRONIC INC

Inventor： SINGHAL RUCHIKA ,  JANZIG DARREN A ,  WAHLSTRAND CARL D ,  SKIME ROBERT M ,  OLSON PAULETTE C

IPC: A61N1/36 ,  A61N1/375

CPC classification number: A61N1/375 ,  A61N1/3605 ,  A61N1/3754 ,  A61N1/3758

Abstract: A modular implantable medical device (101, 201, 301, 401, 801, 901, 1001, 1101, 1201, 1301) permits implantable medical devices to have a smaller profile in order to better fit into locations within the human body. A modular implantable medical device separates various functional components of the implantable medical device into a set of interconnected modules (201-212, 410-412, 510, 701-702, 810). This distributed architecture of a modular implantable medical device may permit the device footprint to be distributed over a larger area while making the profile smaller, and may permit the overall shape of the implantable medical device to better match the body location into which it is to be implanted. An overmold (214, 322, 422, 522, 822, 922, 1022, 1122, 1222, 1322) integrates the modules of a modular implantable medical device into a single structure. In some embodiments the overmold is flexible and provides a biocompatible interface from the component modules and the patient, while restraining potentially harmful intermodule motion.

Abstract translation: 模块化植入式医疗装置（101,201,301,401,801,901,1001,1101,1201,1301）允许植入式医疗装置具有更小的外形以更好地适应人体内的位置。 模块化可植入医疗装置将可植入医疗装置的各种功能部件分成一组互连模块（201-212,410-412,510,701-702,810）。 模块化植入式医疗设备的这种分布式架构可以允许设备占地面积分布在更大的区域上，同时使得外形更小，并且可以允许植入式医疗设备的总体形状更好地匹配其将要成为的身体位置 植入。 包覆模制件（214,322,422,522,822,922,1022,1122,1222,1322）将模块化可植入医疗设备的模块集成到单个结构中。 在一些实施例中，包覆模具是柔性的并且提供来自部件模块和患者的生物相容性界面，同时抑制潜在有害的模块间运动。

公开(公告)号：WO2004052452B1

公开(公告)日：2004-08-19

申请号：PCT/US0338926

申请日：2003-12-09

Applicant: MEDTRONIC INC

Inventor： WAHLSTRAND CARL D ,  JANZIG DARREN A ,  SKIME ROBERT M

IPC: A61N1/36 ,  A61N1/375

CPC classification number: A61N1/375 ,  A61N1/3605 ,  A61N1/3754 ,  A61N1/3758

Abstract: A modular implantable medical device (201, 301, 401, 701, 801) includes a plurality of modules (210-212, 310-312, 410-412, 710, 810, 811) that are at least partially encapsulated by an overmold (214, 314, 422, 722, 822). The modules may be connected by coupling modules, which may be flexible to provide for one or more degrees of relative intermodular motion. The overmold may also be flexible. In order to reduce relative intermodule motion to acceptable direction and/or ranges, the overmold may include one or more motion reduction elements (421, 622, 623, 826).

Abstract translation: 模块化可植入医疗装置（201,301,401,701,801）包括多个模块（210-212,310-312,410-412,710,810,811），所述模块至少部分地被包覆模制 214,314,422,722,822）。 模块可以通过耦合模块连接，耦合模块可以是柔性的，以提供一个或多个相对的模块间运动程度。 包覆成型也可以是柔性的。 为了将相对模块间运动减小到可接受的方向和/或范围，包覆模具可以包括一个或多个运动减少元件（421,622,623,826）。

公开(公告)号：WO2012103419A3

公开(公告)日：2013-01-10

申请号：PCT/US2012022868

申请日：2012-01-27

Applicant: MEDTRONIC INC ,  WAHLSTRAND CARL D ,  HOEGH THOMAS B

Inventor： WAHLSTRAND CARL D ,  HOEGH THOMAS B

IPC: A61N1/05 ,  A61N1/08

CPC classification number: A61N1/08 ,  A61N1/05 ,  A61N1/086

Abstract: Implantable medical leads and systems utilize reflection points within the lead to control radio frequency current that has been induced onto one or more filars. The radio frequency current may be controlled by the reflection points to block at least some of the radio frequency current from reaching an electrode of the lead and to dissipate at least some of the radio frequency current as heat on the filar. Controlling the radio frequency current thereby reduces the amount that is dissipated into bodily tissue through one or more electrodes of the lead and reduces the likelihood of tissue damage. The reflection points may be created by physical changes such as to material or size in the filar and/or in insulation layers that may be present such as an inner jacket about the filar and an outer jacket formed by the body of the lead.

Abstract translation: 植入式医疗引线和系统利用引线内的反射点来控制已被诱导到一个或多个丝状体上的射频电流。 射频电流可以由反射点控制，以阻止射频电流中的至少一些到达引线的电极，并将至少一些射频电流作为热丝散布在丝状体上。 控制射频电流从而减少通过引线的一个或多个电极消散到身体组织中的量，并减少了组织损伤的可能性。 反射点可以通过物理变化产生，例如在丝状物和/或可能存在的绝缘层中的材料或尺寸，例如围绕丝状物的内护套和由引线主体形成的外护套。

公开(公告)号：WO2007112044A3

公开(公告)日：2007-12-21

申请号：PCT/US2007007337

申请日：2007-03-23

Applicant: MEDTRONIC INC ,  WAHLSTRAND CARL D ,  CONROY MARK J ,  KAST JOHN ,  SCOTT ERIK R

Inventor： WAHLSTRAND CARL D ,  CONROY MARK J ,  KAST JOHN ,  SCOTT ERIK R

IPC: A61N1/32

CPC classification number: G01R33/56572 ,  A61B5/055 ,  A61B34/10 ,  A61N1/05 ,  A61N1/0529 ,  A61N1/0551 ,  A61N1/08 ,  A61N1/086 ,  A61N1/3605 ,  A61N1/36125 ,  A61N1/3718 ,  A61N1/375 ,  A61N1/3758 ,  A61N1/378 ,  G01R33/3875 ,  H01M2/0217 ,  H01M2/026 ,  H01M2/0275 ,  H01M2/0285 ,  H01M2/0404 ,  H01M2/1066 ,  H01M2/22 ,  H01M2/263 ,  H01M2/30 ,  H01M10/0431 ,  H01M10/052 ,  H01M10/0525 ,  H01M10/0587 ,  H01M2220/30 ,  Y10T29/49 ,  Y10T29/49002

Abstract: An implantable medical device includes a housing and a circuit board provided within the housing. The circuit board includes a plurality of electronic components electrically coupled thereto. At least one non-functional component is provided on the circuit board and formed from a material that has an electromagnetic permeability configured to reduce the amount of image distortion caused by at least one of the plurality of electronic components when the device is subject to a magnetic field during an MRI scan.

Abstract translation: 可植入医疗装置包括壳体和设置在壳体内的电路板。 电路板包括与其电耦合的多个电子部件。 至少一个非功能部件设置在电路板上，并且由具有电磁渗透性的材料形成，该材料被配置为当该器件经受磁性时减少由至少一个电子元件引起的图像失真量 在MRI扫描期间。

公开(公告)号：WO2006135791A3

公开(公告)日：2007-03-22

申请号：PCT/US2006022565

申请日：2006-06-09

Applicant: MEDTRONIC INC ,  ROONEY ETHAN A ,  WAHLSTRAND CARL D ,  KING GARY W ,  CROSS THOMAS E JR ,  HERUTH KENNETH T ,  WACNIK PAUL W ,  EVANSON JEFFREY S

Inventor： ROONEY ETHAN A ,  WAHLSTRAND CARL D ,  KING GARY W ,  CROSS THOMAS E JR ,  HERUTH KENNETH T ,  WACNIK PAUL W ,  EVANSON JEFFREY S

IPC: A61N1/34 ,  A61N1/05 ,  A61N1/372

CPC classification number: A61N1/36071 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0553 ,  A61N1/0558 ,  A61N1/36021 ,  A61N1/37205 ,  A61N1/37211 ,  A61N1/375 ,  A61N1/3756

Abstract: Delivery of peripheral nerve field stimulation (PNFS) in combination with one o more other therapies is described. The other therapy delivered in combination with PNF may be, for example, a different type of neurostimulation, such as spinal cord stimulation (SCS), or a drug. PNFS and the other therapy may be delivered simultaneously, in an alternating fashion, according to a schedule, and/or selectively, e.g., in response to a request received from a patient or clinician. A combination therapy that includes PNFS may be able to more completely address complex or multifocal pain than would be possible through delivery of either PNFS or other therapies alone. Further, the combination of PNFS with one or more other therapies may reduce the likelihood that neural accommodation will impair the perceived effectiveness PNFS or the other therapies.

Abstract translation: 描述了外周神经区域刺激（PNFS）与一种或多种其他疗法的结合。 与PNF组合递送的另一疗法可以是例如不同类型的神经刺激，例如脊髓刺激（SCS）或药物。 PNFS和其他治疗可以根据时间表以交替方式同时递送，和/或选择性地，例如响应于从患者或临床医生接收到的请求。 包括PNFS的联合治疗可能能够更全面地解决复杂或多焦点疼痛，而不仅仅是通过传送PNFS或其他疗法来实现。 此外，PNFS与一种或多种其它疗法的组合可以降低神经调节可能损害所感知的有效性PNFS或其他疗法的可能性。

公开(公告)号：WO2004052455B1

公开(公告)日：2004-09-02

申请号：PCT/US0338938

申请日：2003-12-09

Applicant: MEDTRONIC INC

Inventor： JANZIG DARREN A ,  WAHLSTRAND CARL D ,  SKIME ROBERT M ,  LENT MARK S ,  MIESEL KEITH A ,  CABAK JAMES E

IPC: A61N1/36 ,  A61N1/375

CPC classification number: A61N1/375 ,  A61N1/3605 ,  A61N1/3754 ,  A61N1/3758

Abstract: In an implantable medical device (101, 201, 401A-F, 501, 601, 701, 801, 901) having individual modules (103-105, 210-212, 410-412, 510-512, 610-611, 711-713, 811-812, 911-912, 1110-1111, 1201-1202), a coupling module (521, 612, 721, 722, 821, 921, 1001, 1101, 1222) couples the modules to one another. The coupling module supports electrical and/or mechanical coupling of the modules. The coupling module may assume a variety of shapes or configurations. The various embodiments of the coupling module may offer the modules varying degrees of freedom of movement relative to one another.

Abstract translation: 在具有单独模块（103-105,210-212,410-412,510-512,610-611,711 -115）的可植入医疗装置（101,201,401A-F，501,601,701,801,901） （例如，713,811-812,911-912,1110-1111,1201-1202），耦合模块（521,612,721,722,821,921,1001,1101,1222）将模块彼此耦合。 耦合模块支持模块的电气和/或机械耦合。 耦合模块可以采取各种形状或配置。 耦合模块的各种实施例可以提供模块相对于彼此改变运动自由度。

公开(公告)号：WO2004052456B1

公开(公告)日：2004-08-26

申请号：PCT/US0338939

申请日：2003-12-09

Applicant: MEDTRONIC INC

Inventor： WAHLSTRAND CARL D ,  SINGHAL RUCHIKA ,  SKIME ROBERT M

IPC: A61N1/36 ,  A61N1/375

CPC classification number: A61N1/375 ,  A61N1/3605 ,  A61N1/3754 ,  A61N1/3758

Abstract: An implantable medical device (10, 80, 90, 120, 130, 140, 150, 170, 180) includes a plurality of separately housed and flexibly interconnected modules (30, 32, 34, 172, 182). A first module (30) includes a control electronics within a first housing (36), and may be coupled to a second module (32) that includes a second housing (38) by a flexible interconnect member (44, 46, 174, 184). In some embodiments, an overmold (48, 82, 92, 122, 132, 176, 186), which may be flexible, at least partially encapsulates the first and second housings. The second module may be a power source module that includes a power source, such as a rechargeable battery, within the second housing. The implantable medical device may also include a third module, such as a recharge module that includes a coil within a third housing. The overmold may at lest partially encapsulate the third housing, or the third module may be tethered to the overmold by a flexible tether member (124). A flexible interconnect member and/or flexible overmold may allow multiples degrees of freedom of movement between modules of an implantable medical device.

Abstract translation: 可植入医疗装置（10,80,90,120,130,140,​​150,170,180）包括多个单独容纳且柔性互连的模块（30,32,34,172,182）。 第一模块（30）包括位于第一壳体（36）内的控制电子器件，并且可以通过柔性互连构件（44,46,174,184）耦合到包括第二壳体（38）的第二模块（32） ）。 在一些实施例中，可以是柔性的包覆模制件（48,82,92,122,132,176,186）至少部分地包封第一壳体和第二壳体。 第二模块可以是在第二壳体内包括诸如可再充电电池的电源的电源模块。 可植入医疗装置还可以包括第三模块，例如包括第三外壳内的线圈的再充电模块。 包胶模可以部分地包封第三壳体，或者第三模块可以通过柔性系绳构件（124）系连到包覆模制件。 柔性互连件和/或柔性包覆模制件可允许可植入医疗设备的模块之间的多个运动自由度。

公开(公告)号：WO2012068385A2

公开(公告)日：2012-05-24

申请号：PCT/US2011061208

申请日：2011-11-17

Applicant: MEDTRONIC INC ,  SEELEY DALE F ,  RAHN JASON D ,  HEGLAND MICHAEL T ,  WAHLSTRAND CARL D

Inventor： SEELEY DALE F ,  RAHN JASON D ,  HEGLAND MICHAEL T ,  WAHLSTRAND CARL D

IPC: A61N1/375

CPC classification number: A61N1/3752 ,  A61N1/3754 ,  H01R24/00 ,  H01R24/76 ,  H01R2107/00 ,  Y10T29/49169

Abstract: An implantable electrical medical device system includes a device body portion having a plurality of contacts operably coupled to discrete channels of electronics. One or more swappable headers may be attached to the device body portion by an end user, such as an implanting physician, to operably couple internal lead receptacle contacts in the header to the contacts of the device body portion. The swappable headers may have lead receptacles configured to receive differing types or combinations of leads, allowing an end user to select one or more appropriate headers as desired.

Abstract translation: 一种可植入的电医疗设备系统包括设备主体部分，该设备主体部分具有可操作地耦合到离散电子通道的多个触点。 一个或多个可置换的头部可由最终用户（例如植入医师）附接到装置主体部分，以将头部中的内部引线插座触点可操作地耦合到装置主体部分的触点。 可交换头部可以具有配置成接收不同类型或引线组合的引线插座，允许最终用户根据需要选择一个或多个适当的头部。

公开(公告)号：WO2007112070A3

公开(公告)日：2007-11-29

申请号：PCT/US2007007384

申请日：2007-03-23

Applicant: MEDTRONIC INC ,  KAST JOHN ,  WAHLSTRAND CARL D ,  CONROY MARK J ,  SCOTT ERIK R

Inventor： KAST JOHN ,  WAHLSTRAND CARL D ,  CONROY MARK J ,  SCOTT ERIK R

IPC: A61N1/32

CPC classification number: G01R33/56572 ,  A61B5/055 ,  A61B34/10 ,  A61N1/05 ,  A61N1/0529 ,  A61N1/0551 ,  A61N1/08 ,  A61N1/086 ,  A61N1/3605 ,  A61N1/36125 ,  A61N1/3718 ,  A61N1/375 ,  A61N1/3758 ,  A61N1/378 ,  G01R33/3875 ,  H01M2/0217 ,  H01M2/026 ,  H01M2/0275 ,  H01M2/0285 ,  H01M2/0404 ,  H01M2/1066 ,  H01M2/22 ,  H01M2/263 ,  H01M2/30 ,  H01M10/0431 ,  H01M10/052 ,  H01M10/0525 ,  H01M10/0587 ,  H01M2220/30 ,  Y10T29/49 ,  Y10T29/49002

Abstract: An implantable medical device includes a housing having a shimming material provided in contact with an inner surface of the housing to reduce the amount of image distortion caused by the implantable medical device when the device is subjected to MRI scans.

Abstract translation: 可植入医疗装置包括壳体，该壳体具有提供为与壳体的内表面接触的匀场材料，以减少当装置经受MRI扫描时由可植入医疗装置引起的图像失真的量。

公开(公告)号：WO2006133445A3

公开(公告)日：2007-02-08

申请号：PCT/US2006022721

申请日：2006-06-09

Applicant: MEDTRONIC INC ,  ROONEY ETHAN A ,  WAHLSTRAND CARL D ,  KING GARY W ,  CROSS THOMAS E ,  STONE RICHARD T

Inventor： ROONEY ETHAN A ,  WAHLSTRAND CARL D ,  KING GARY W ,  CROSS THOMAS E ,  STONE RICHARD T

IPC: A61N1/05

CPC classification number: A61N1/0531 ,  A61N1/0534 ,  A61N1/0553 ,  A61N1/36071 ,  A61N1/37211

Abstract: The disclosure describes an implantable medical lead for delivering stimulation to a patient. Electrodes may be located on two or more surfaces of the lead to, for example, selectively deliver stimulation to one or more tissue layers within the patient. The lead may be implanted within or between intra-dermal, deep dermal, or subcutaneous tissue layers, and may be used to, for example, deliver peripheral nerve field stimulation to treat pain experienced by the patient at the site at which the lead is implanted. The lead may comprise a paddle lead or a multiple level lead, e.g., a lead having a plurality of flat or paddle shaped lead bodies arranged in substantially parallel planes. Further, the lead may include fixation structures on the distal end, proximal end, or both ends to prevent migration.

Abstract translation: 本公开描述了用于将刺激递送给患者的可植入医疗引线。 电极可以位于引线的两个或更多个表面上，以例如选择性地将刺激递送到患者体内的一个或多个组织层。 铅可以植入在真皮内，深层皮肤或皮下组织层之内或之间，并且可以用于例如递送周围神经区域刺激以治疗患者在植入铅的部位所经历的疼痛 。 引线可以包括桨引线或多级引线，例如具有布置在基本上平行的平面中的多个扁平或桨状引线的引线。 此外，引线可以包括远端，近端或两端的固定结构，以防止迁移。