公开(公告)号：ES2355615T3

公开(公告)日：2011-03-29

申请号：ES03719946

申请日：2003-04-25

Applicant: MILLIPORE CORP

Inventor： PROULX STEPHEN ,  ALMASIAN JOSEPH ,  RENGANATH NAREN ,  TINGLEY STEPHEN ,  MORRISSEY MARTIN

IPC: A61M39/10 ,  B67D99/00 ,  A61M39/16 ,  A61M39/18 ,  A61M39/22 ,  F16K3/26 ,  F16K15/18 ,  F16K17/40 ,  F16L37/107

Abstract: Un dispositivo de transferencia estéril (2; 61) para fluidos en forma de un conector o válvula para usar en la industria farmacéutica y biofarmacéutica que comprenden un cuerpo (4; 180) que tiene un ánima (10; 76; 182) formada a través de al menos una parte de su interior, teniendo el cuerpo (4; 180) un primer extremo (6) que incluye una cara diseñada para ser unida a un componente de aguas arriba (54; 72), definiendo dicho primer extremo (6) un lado de aguas arriba del dispositivo; y un émbolo buzo o empujador (18; 70; 181) contenido dentro del ánima, teniendo dicho émbolo buzo un primer extremo y pudiendo moverse en el ánima entre una posición cerrada, en la que no hay creada ninguna comunicación de fluido a través del dispositivo entre dicho lado de aguas arriba del dispositivo y un lado de aguas abajo del dispositivo, y una posición abierta en la que es creada tal comunicación de fluido a través del dispositivo, en el que dicho lado de aguas abajo del dispositivo está adaptado para ser conectado a un componente de aguas abajo (56; 64) y está definido por un puerto o abertura (30; 62) sobre dicho cuerpo (4; 180) o dicho émbolo buzo, respectivamente, aguas abajo de dicho primer extremo (6) de dicho cuerpo (4; 180); en el que dicho primer extremo de dicho émbolo buzo (18; 70; 181), cuando está en la posición cerrada, está en alineación con dicha cara de dicho primer extremo (6) de dicho cuerpo (4; 180) que juntos forman una entrecara o enlace (46; 104; 183) que se puede esterilizar con vapor y una barrera estéril contra el entorno para el resto del interior de dicho cuerpo (4; 180), dicho émbolo buzo (18; 70; 181) y el componente de aguas abajo (56; 64); y en el que dicho émbolo buzo comprende una empuñadura (34; 112) para permitir el cierre/apertura selectivo del dispositivo.

公开(公告)号：AU2003256821A1

公开(公告)日：2004-02-16

申请号：AU2003256821

申请日：2003-07-24

Applicant: MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  NAUSEDA CURTIS ,  NGUYEN CHAU ,  PROULX STEPHEN ,  RENGANATH NAREN ,  ALMASIAN JOSEPH ,  BELONGIA BRETT ,  LENTIE FRANK

IPC: A61M39/02 ,  A61M1/16 ,  A61M39/14 ,  A61M39/18 ,  A61M39/22 ,  F16L29/00 ,  F16K3/00

Abstract: A sterile to sterile connection device comprising a connector and one or more coupling devices. The connector has body portion which has two openings sealed from the environment so as to form a sterile environment within the connector. At least one of the openings being sealed from the environment by a sterile barrier plug. The connector also has a port capable movement within the body of the connector to at least an open and a closed position. The coupling device is formed of a body having two openings and a stem having a bore through at least a portion of the stem. The stem is contained within the body and capable of moving at least linearly through the body between a first and second stem position. One of the openings of the stem is sealed from the environment by a sterile barrier plug and the other is sealed to a presterilized component. The coupling device opening containing the sterile barrier plug is attached to either the inlet or outlet of the connector.

公开(公告)号：SG11201811419PA

公开(公告)日：2019-01-30

申请号：SG11201811419P

申请日：2017-05-23

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN

IPC: F16L33/22

Abstract: A clamp device for a barb member having a barbed region for disposing within an end of a flexible tube having an outer surface. The clamp device includes a flexible member including a body having a plurality of finger members compressible between a first resting position and a second clamping position; at least one of the flexible finger members having a radially inwardly extending tooth; the body having a through bore and an outer surface comprising threads; the flexible member being slidable over the barbed region and the outer surface of the flexible tube; a compression member having a body having a through bore and an inner surface including threads; the compression member being slidable over the flexible member; wherein upon threadingly engaging the compression member with the flexible member, the compression member compresses the finger member against the barb member.

公开(公告)号：IN4298DEN2015A

公开(公告)日：2015-10-16

申请号：IN4298DEN2015

申请日：2015-05-20

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  PEREIRA BRIAN

IPC: B01F3/12

Abstract: A disposable container such as a deformable bag for a fluid having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing dispersing homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped which allows very low fluid level mixing dispensing while mixing and a reduction or elimination of vortex formation.

公开(公告)号：SG11201503669XA

公开(公告)日：2015-06-29

申请号：SG11201503669X

申请日：2013-11-05

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  PEREIRA BRIAN

IPC: B01F3/12

Abstract: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.

公开(公告)号：SG191998A1

公开(公告)日：2013-08-30

申请号：SG2013054515

申请日：2012-02-28

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  HARTNETT JEFF

Abstract: The present invention is a device for fluid movement and method of making the same. The device has a core element comprised of a preformed barbed fitting having two or more barbed extensions. Each extension has a central bore connected to the central bores of the other extensions so as to provide fluid communications between them. A tube having a central bore is fitted over the barb of each extension. A molded housing is formed over the fitting and tubes to form the device.

公开(公告)号：DE60335796D1

公开(公告)日：2011-03-03

申请号：DE60335796

申请日：2003-04-25

Applicant: MILLIPORE CORP

Inventor： PROULX STEPHEN ,  ALMASIAN JOSEPH ,  RENGANATH NAREN ,  TINGLEY STEPHEN ,  MORRISSEY MARTIN

IPC: A61M39/22 ,  B67D99/00 ,  A61M39/10 ,  A61M39/16 ,  A61M39/18 ,  F16K3/26 ,  F16K15/18 ,  F16K17/40 ,  F16L37/107

公开(公告)号：AT495787T

公开(公告)日：2011-02-15

申请号：AT03719946

申请日：2003-04-25

Applicant: MILLIPORE CORP

Inventor： PROULX STEPHEN ,  ALMASIAN JOSEPH ,  RENGANATH NAREN ,  TINGLEY STEPHEN ,  MORRISSEY MARTIN

IPC: A61M39/10 ,  B67D99/00 ,  A61M39/16 ,  A61M39/18 ,  A61M39/22 ,  F16K3/26 ,  F16K15/18 ,  F16K17/40 ,  F16L37/107

Abstract: A sterile transfer device (2) for fluids, be they liquids or gases. It comprises a body (4) having a bore (10) formed through at least a portion of its interior, the body (4) having a first end (6) containing a face designed to be attached to an upstream component (54;72). Contained within the bore is a plunger (18;70;108), the plunger having a first end and being movable within the bore, wherein the first end of the plunger (18;70;108), when in a closed position, is in alignment with the face of the first end (6) of the body (4), which combined form a steamable surface (46;104) and a sterile barrier against the environment to the rest of the interior of the body (4) and the plunger (18;70;108). A cam slot (36) is formed in the body (4), and a cam (32) is provided on the plunger (18;70;108), wherein the cam (32) rides in the cam slot (36) such that a rearward and forward movement and a rotation of the plunger (18;70;108) within the bore (10) is defined.

公开(公告)号：CA3139834A1

公开(公告)日：2021-03-04

申请号：CA3139834

申请日：2020-08-06

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  KING CONOR ,  BOROZENETS PHILIP

IPC: B25J21/00 ,  B01L1/04 ,  B25J21/02

Abstract: An apparatus for use with an isolator, including a crown for releasably joining with a beta port of the isolator, wherein the crown includes at least one anchoring support; a spring hook on at least one end of the at least one anchoring support; a needle block including at least one through hole for having a needle positioned therein, wherein the at least one needle is joined with tubing; a yoke; and a biasing element releasably joined with the yoke and the at least one anchoring support; wherein the needle block is releasably joined to the crown.

公开(公告)号：SG11201901782TA

公开(公告)日：2019-05-30

申请号：SG11201901782T

申请日：2017-10-23

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN

IPC: B01D35/28

Abstract: WO 18/085 07 0 Al 10 10' 1 0\" FIG. 2 A (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 11 May 2018 (11.05.2018) WIPO I PCT IiiimmoimiolollmonoloommuloonmoilomovoimIE (10) International Publication Number WO 2018/085070 Al (51) International Patent Classification: BOLD 35/28 (2006.01) (21) International Application Number: PCT/US2017/057856 (22) International Filing Date: 23 October 2017 (23.10.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/416,309 02 November 2016 (02.11.2016) US (71) Applicant: EMD MILLIPORE CORPORATION [US/US]; 400 Summit Drive, Burlington Massachusetts 01803 (US). (72) Inventor: MORRISSEY, Martin; c/o EMD Millipore Corporation, 400 Summit Drive, Burlington, Massachusetts 01803 (US). (74) Agent: LEMACK, Kevin S. et al.; 176 E. Main Street, Suite 5, Westboro, Massachusetts 01581 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) (54) Title: CONTAINER FOR SEPARATING MICROCARRIERS FROM CELL CULTURE FLUIDS (57) : Containers for separating microcarriers from a cell culture fluid that offer a greater efficiency of filtration of cell cul- ture fluids containing microcarriers relative to systems described in the art. The container may include a first compartment that may include a sterile collapsible bag, an inlet port providing a fluid path into the first compartment and an outlet port providing a fluid path exiting the first compartment; and a second compartment fluid- ly connected with the inlet port of the first compartment and in- cluding a plurality of independent or discrete microcarrier receiv- ing regions defined by boundary walls which are partially or fully porous and having a porosity sufficient to retain the microcarrier s inside the second compartment, while allowing the cell culture fluid to pass through the second compartment into the outlet port of the first compartment, where the cell culture fluid can be col- lected.