公开(公告)号：WO2014085035A3

公开(公告)日：2015-07-16

申请号：PCT/US2013068375

申请日：2013-11-05

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  PEREIRA BRIAN

IPC: B01F13/08

CPC classification number: B01F15/0085 ,  B01F7/00241 ,  B01F13/0827 ,  B01F15/00487 ,  B01F2215/0034 ,  B01F2215/0073 ,  C12M23/14 ,  C12M27/02

Abstract: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.

Abstract translation: 用于流体的一次性容器，例如可变形袋，具有一个或多个入口和一个或多个出口以及容器内的叶轮组件，用于引起包含或添加的一种或多种成分的混合，分散，均化和/或循环 到容器 容器内可容纳液体的区域是漏斗形的，其允许非常低的液面混合，分配同时混合，以及减少或消除涡流形成。

公开(公告)号：WO2012150991A2

公开(公告)日：2012-11-08

申请号：PCT/US2012026858

申请日：2012-02-28

Applicant: EMD MILLIPORE CORP ,  MORRISSEY MARTIN ,  HARTNETT JEFF

Inventor： MORRISSEY MARTIN ,  HARTNETT JEFF

IPC: F16L47/02 ,  F16L47/26

CPC classification number: B29C45/14467 ,  A61M39/12 ,  A61M2039/1083 ,  A61M2039/1088 ,  B29C45/14598 ,  B29L2031/24 ,  F16L33/34 ,  F16L47/32

Abstract: The present invention is a device for fluid movement and method of making the same. The device has a core element comprised of a preformed barbed fitting having two or more barbed extensions. Each extension has a central bore connected to the central bores of the other extensions so as to provide fluid communications between them. A tube having a central bore is fitted over the barb of each extension. A molded housing is formed over the fitting and tubes to form the device.

Abstract translation: 本发明是一种流体移动装置及其制造方法。 该装置具有由具有两个或更多个有倒钩的延伸部的预成型的倒钩配件构成的芯部元件。 每个延伸部具有连接到另一个延伸部的中心孔的中心孔，以便在它们之间提供流体连通。 具有中心孔的管装配在每个延伸部的倒钩上。 模制的壳体形成在配件和管上以形成装置。

公开(公告)号：WO2009148499A3

公开(公告)日：2010-05-27

申请号：PCT/US2009003077

申请日：2009-05-18

Applicant: MILLIPORE CORP ,  MORRISSEY MARTIN ,  KELLY JAMES E ,  WONG DENNIS ,  MELLO STEVE ,  WEISSENBACH JEAN-LOUISE

Inventor： MORRISSEY MARTIN ,  KELLY JAMES E ,  WONG DENNIS ,  MELLO STEVE ,  WEISSENBACH JEAN-LOUISE

IPC: B67D7/78 ,  B67D99/00

CPC classification number: B67D7/78 ,  B65D1/20 ,  B67D1/0801

Abstract: A disposable container for fluid is provided. The container has a vortex breaker positioned adjacent the container outlet and a fluid diverter positioned adjacent each inlet to the container.

Abstract translation: 提供了用于流体的一次性容器。 容器具有邻近容器出口定位的涡流破碎器，并且与容器的每个入口相邻的流体分配器。

公开(公告)号：ES2454190T3

公开(公告)日：2014-04-09

申请号：ES03771865

申请日：2003-07-24

Applicant: MILLIPORE CORP ,  EMD MILLIPORE CORP

Inventor： ALMASIAN JOSEPH ,  BELONGIA BRETT ,  LENTIE FRANK ,  MORRISSEY MARTIN ,  NAUSEDA CURTIS ,  NGUYEN CHAU ,  PROULX STEPHEN ,  RENGANATH NAREN

IPC: A61M39/02 ,  F16L29/00 ,  A61M1/16 ,  A61M39/14 ,  A61M39/18 ,  A61M39/22 ,  F16K3/00

Abstract: Un dispositivo de conexión para establecer una conexión de estéril a estéril, que comprende: un conector (4; 100) que tiene una primera y una segunda abertura (14, 16; 116, 108), cada una de dicha primera y segunda abertura (14, 16; 116, 108) se adaptan para ser selladas respecto el ambiente para formar un ambiente estéril dentro del conector (4; 100), y dicha segunda abertura (16; 108) se adapta para ser sellada con un componente estéril aguas abajo, y un orificio (10; 102) con capacidad de ser movido entre por lo menos dos posiciones con respecto al conector (4; 100) incluida una posición de cerrado y una posición de abierto; y un dispositivo de acoplamiento (6; 101) que incluye un cuerpo (18; 124) que tiene una tercera abertura (24; 129), y un tronco (20; 134) que tiene una cuarta abertura (28; 126), en donde dicho tronco (20; 134) está contenido dentro del cuerpo (18; 124) y con capacidad de moverse por lo menos linealmente a través del dispositivo de conexión entre una primera, una segunda y una tercera posición del tronco, en las que la tercera posición del tronco (20; 134) forma un sello hermético y ajustado con una parte de dicha segunda abertura (16; 108) de dicho conector (4; 100), en donde dicha tercera abertura (24, 28; 126, 129) se sella del ambiente con un segundo tapón estéril de barrera (22; 138) y se conecta o se puede conectar a dicha primera abertura (14, 116) del conector (4; 100), en donde dicha cuarta abertura (28; 126) se adapta para sellarse con un componente pre-esterilizado, caracterizado porque dicha primera abertura (14; 116) se sella del ambiente por un primer tapón estéril de barrera (12; 118), y porque dicho orificio (10; 102) tiene una primera abertura (30; 104), que tiene una dimensión adecuada para contener dicho primer y dicho segundo tapón estéril de barrera (12, 22; 118, 138), y una segunda abertura (32) que tiene una dimensión para permitir el avance del tronco (20; 134) del dispositivo de acoplamiento (6; 101) a través de ella, en donde dicho tronco (20; 134) se adapta para mover dichos primer y segundo tapones estériles de barrera (12, 22; 118, 138) adentro de una primera abertura (30; 104) de dicho orificio (10; 102) cuando dicho orificio está en su posición de cerrado y el tronco (20; 134) se mueve desde su primera a su segunda posición, y en donde dicho tronco (20; 134) se adapta para moverse a su tercera posición cuando dicho orificio (10; 102) se ha movido a la posición de abierto.

公开(公告)号：JP2010274260A

公开(公告)日：2010-12-09

申请号：JP2010124907

申请日：2010-05-31

Applicant: Millipore Corp ,  ミリポア・コーポレイションMillipore Corporation

Inventor： MORRISSEY MARTIN ,  WONG DENNIS

IPC: B01D63/08 ,  B01D61/20 ,  B01D61/22 ,  B01D63/00

CPC classification number: B01D35/14 ,  B01D61/20 ,  B01D63/084 ,  B01D2313/04 ,  B01D2313/23 ,  B01D2313/44 ,  B01D2313/54 ,  C02F2209/03 ,  G01L7/082 ,  G01N1/10 ,  G01N1/4005 ,  Y10T436/25 ,  Y10T436/25375

Abstract: PROBLEM TO BE SOLVED: To provide a filtration apparatus including a disposable tangential flow filtration liner with sensor mount. SOLUTION: The filtration apparatus is provided that includes: a top plate; a bottom plate disposed with a space from the top plate; a filtration member disposed between the top plate and bottom plate; at least one disposable liner disposed between the top plate and filtration member and having a fluid inlet, a fluid outlet, at least one flow path in the liner and at least one sensor port communicated with the flow path by the fluid; a diaphragm sealed in at least one sensor support; and a sensor detachably connected to the sensor support for sensing the pressure in at least one flow path via the diaphragm with no contact with the fluid in the flow path. COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：提供一种包括具有传感器安装座的一次性切向流过滤衬套的过滤装置。

解决方案：提供了一种过滤装置，其包括：顶板; 从顶板设置有空间的底板; 设置在顶板和底板之间的过滤构件; 布置在顶板和过滤构件之间并具有流体入口，流体出口，衬套中的至少一个流动路径和由流体与流路连通的至少一个传感器端口的至少一个一次性衬垫; 密封在至少一个传感器支架中的隔膜; 以及可拆卸地连接到所述传感器支撑件的传感器，用于感测经由所述隔膜的至少一个流动路径中的压力，而不与所述流动路径中的流体接触。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2011031239A

公开(公告)日：2011-02-17

申请号：JP2010175454

申请日：2010-08-04

Applicant: Millipore Corp ,  ミリポア・コーポレイションMillipore Corporation

Inventor： MORRISSEY MARTIN ,  WONG DENNIS

IPC: B01D63/08

CPC classification number: B01D63/082 ,  B01D2313/02 ,  B01D2313/44 ,  Y02A20/131

Abstract: PROBLEM TO BE SOLVED: To provide a disposable built-in tangential flow filtration liner for compressing specific TFF components separately from compression of the entire apparatus, which is created by a holder, so as to avoid the leak of fluids from the apparatus.
SOLUTION: A combination of a first liner 16, one or more filtration elements 20, and a second liner 22 is compressed separately from compression of the entire assembly. For this purpose, the second liner 22 can comprise an appropriate receiving member 75 for receiving a clamp mechanism 70. The filtration element 20 is held between the first and the second liners. A rod with a screw groove, a screw, a bolt and/or a pin 70 or other members extending from the first liner 16 is screwed into each receiving member 75 of the second liner 22, so that each component is pressed below members relating to sealing.
COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：提供一种一次性内置的切向流过滤衬套，用于压缩特定TFF部件，与保持器产生的整个装置的压缩分开，以避免流体从设备泄漏 。 解决方案：第一衬套16，一个或多个过滤元件20和第二衬套22的组合与整个组件的压缩分开地压缩。 为此，第二衬套22可以包括用于接收夹紧机构70的适当的接收构件75.过滤元件20保持在第一和第二衬垫之间。 具有螺纹槽，螺钉，螺栓和/或销70或从第一衬套16延伸的其它构件的杆被拧入第二衬套22的每个接收构件75中，使得每个构件被压在与 密封。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2010223946A

公开(公告)日：2010-10-07

申请号：JP2010023784

申请日：2010-02-05

Applicant: MILLIPORE CORP

Inventor： DELBOS CECILE ,  WEISSENBACH JEAN-LOUIS ,  VIGNA JAMES ,  MORRISSEY MARTIN ,  REINBIGLER RENE

IPC: G01J5/00 ,  G01K13/02 ,  G01L19/00 ,  G01L19/06

Abstract: PROBLEM TO BE SOLVED: To provide a device for determining a temperature of a fluid flowing in a pipe which is equipped with connector of single-time use, similar to a device in a conventional technique. SOLUTION: In the device for determining the physical values of the liquid flowing through the pipe, without contacting the liquid, the device includes a sensor (3) for the physical value; a connector (2) to insert into the pipe including a flexible film (6) for pressure sensor forming a wall of an inner passage (13), extending between two apertures (11, 12) and the inner passage (13); and means (27, 62) for fastening the sensor (3) onto the connector (2). The sensor is such that the temperature sensor (3) fastened to the connector (2) with the sensitive part of the sensor (3) is directed toward the film (6). COPYRIGHT: (C)2011,JPO&INPIT

公开(公告)号：JP2013234761A

公开(公告)日：2013-11-21

申请号：JP2013161276

申请日：2013-08-02

Applicant: Emd Millipore Corp ,  イー・エム・デイー・ミリポア・コーポレイシヨン

Inventor： PROULX STEPHEN ,  ALMASIAN JOSEPH ,  RENGANATH NAREN ,  TINGLEY STEPHEN ,  MORRISSEY MARTIN

IPC: B67D99/00 ,  F16K3/24 ,  A61M39/10 ,  A61M39/16 ,  A61M39/18 ,  A61M39/22 ,  F16K3/26 ,  F16K15/18 ,  F16K17/40 ,  F16K31/524 ,  F16K41/04 ,  F16L37/107

CPC classification number: F16K5/00 ,  A61M39/10 ,  A61M39/16 ,  A61M39/18 ,  A61M39/22 ,  A61M2039/1027 ,  A61M2039/222 ,  F16K3/265 ,  F16K13/04 ,  F16K15/18 ,  F16L37/107

Abstract: PROBLEM TO BE SOLVED: To provide a connector of a system in which a connection part is subjected to steam sterilization, the connector being disposable after used.SOLUTION: The present invention relates to a sterile transfer device. The device is comprised of a body having a bore formed through at least a portion of its interior. It is preferable that the bore is a center hole formed in the whole length of the body. A plunger is contained inside of the hole. The body has a first and a second end. The first end contains a surface designed to be attached to an upstream component. The second end is connected to a downstream component such as a filter, a pipeline, a sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it is in a closed position is in alignment with the surface of the body, which collectively forms a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components.

Abstract translation: 要解决的问题：为了提供连接部件进行蒸汽灭菌的系统的连接器，连接器在使用后是一次性的。解决方案：本发明涉及无菌转移装置。 该装置包括具有通过其内部的至少一部分形成的孔的主体。 优选地，孔是形成在主体的整个长度上的中心孔。 孔内装有柱塞。 身体有第一和第二端。 第一端包含设计成连接到上游部件的表面。 第二端连接到诸如过滤器，管道，样品袋等的下游部件。 柱塞具有相应的第一和第二端。 当柱塞处于关闭位置时，柱塞的第一端与主体的表面对准，这些表面共同形成可蒸发的表面和抵抗环境的无菌屏障抵抗主体内部的其余部分，柱塞和下游 组件。

公开(公告)号：JP2010203432A

公开(公告)日：2010-09-16

申请号：JP2010030778

申请日：2010-02-16

Applicant: Millipore Corp ,  ミリポア・コーポレイションMillipore Corporation

Inventor： MORRISSEY MARTIN

IPC: F04B43/02

CPC classification number: F04B43/082 ,  Y10T137/86035

Abstract: PROBLEM TO BE SOLVED: To provide an assembly for a pump, a pump and a pumping system which includes a disposable flexible bladder and disposable conduits with the pump through which the fluid to pumped is passed in a manner such that the pump components are never exposed to the fluid. SOLUTION: The pump has the disposable bladder, the disposable conduit and a check valve for controlling a fluid flow passing through the bladder and the conduit when the bladder is alternately compressed and expanded. The use of the disposable conduit and bladder eliminates the need for hygienically regenerating the pump between uses. The pump can be utilized in a fluid delivery system such as tangential flow filtration. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：提供一种用于泵，泵和泵送系统的组件，其包括一次性柔性气囊和具有泵的一次性管道，待泵送的流体通过该泵通过，使得泵组件 永远不会暴露于流体。 解决方案：泵具有一次性气囊，一次性导管和止回阀，用于在气囊交替压缩和膨胀时控制通过气囊和导管的流体流动。 使用一次性导管和气囊消除了在使用之间卫生地再生泵的需要。 泵可用于流体输送系统，例如切向流过滤。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：EP2255865B1

公开(公告)日：2017-06-21

申请号：EP10164404

申请日：2010-05-28

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  WONG DENNIS

IPC: B01D61/20 ,  B01D63/08

CPC classification number: B01D35/14 ,  B01D61/20 ,  B01D63/084 ,  B01D2313/04 ,  B01D2313/23 ,  B01D2313/44 ,  B01D2313/54 ,  C02F2209/03 ,  G01L7/082 ,  G01N1/10 ,  G01N1/4005 ,  Y10T436/25 ,  Y10T436/25375