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31.发明专利
公开(公告)号：SI2829539T1
公开(公告)日：2017-04-26
申请号：SI201430163
申请日：2014-07-22
Applicant: SERVIER LAB , VERNALIS (R&D) LTD
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , FEJES IMRE , TATAI JANOS , NYERGES MIKLOS , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , DURAND DIDIER
IPC: C07D401/00 , A61K31/00 , A61P35/00 , A61P37/00 , C07D405/00 , C07D471/00 , C07D491/00 , C07D498/00
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32.发明专利
公开(公告)号：AP4028A
公开(公告)日：2017-02-04
申请号：AP2014007882
申请日：2013-01-23
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： LE DIGUARHER THIERRY , CASARA PATRICK , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , GRAHAM CHRISTOPHER JOHN , CHEN I-JEN , GENESTE OLIVIER , HICKMAN JOHN , DEPIL STEPHANE , LE TIRAN ARNAUD , NYERGES MIKLOS , DE NANTEUIL GUILLAUME
IPC: C07D471/00 , A61K31/407 , A61K31/436 , A61K31/453 , A61P35/00 , A61P37/00 , C07D471/04 , C07D487/04 , C07D491/052
Abstract: wherein Ra, Rb, Rc, Rd, R1, R2, R3, R4, R5, X, Y and Het are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
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33.发明专利
公开(公告)号：SI2829545T1
公开(公告)日：2016-10-28
申请号：SI201430059
申请日：2014-07-22
Applicant: SERVIER LAB , VERNALIS (R&D) LTD
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公开(公告)号：CA2861160C
公开(公告)日：2016-08-09
申请号：CA2861160
申请日：2013-01-23
Applicant: SERVIER LAB , VERNALIS (R&D) LTD
Inventor： LE DIGUARHER THIERRY , CASARA PATRICK , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , GRAHAM CHRISTOPHER JOHN , CHEN I-JEN , GENESTE OLIVIER , HICKMAN JOHN , DEPIL STEPHANE , LE TIRAN ARNAUD , NYERGES MIKLOS , DE NANTEUIL GUILLAUME
IPC: C07D471/00 , A61K31/407 , A61K31/4353 , A61K31/436 , A61P35/00 , A61P37/00 , C07D471/04 , C07D487/04 , C07D491/052
Abstract: The invention relates to compounds of formula (I): (See Formula I) wherein R a, R b, R c, R d, R1, R2, R3, R4, R5, X, Y and Het are as defined in the description, as well as to a process for preparing said compounds and compositions comprising same. The compounds are believed to have valuable pharmacological properties in the field of apoptosis and cancer treatment.
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公开(公告)号：CA2856886C
公开(公告)日：2016-08-02
申请号：CA2856886
申请日：2014-07-14
Applicant: SERVIER LAB , VERNALIS (R&D) LTD
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN
IPC: C07F9/6558 , A61K31/5377 , A61P35/00
Abstract: Composés de formule (I) : (voir formule I) dans laquelle X, Y, A1, A29 R a, R b, R c, R d, R3, R4, T et R5 sont tels que définis dans la description.
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Patent Agency Ranking
公开(公告)号：AU2014295101A1
公开(公告)日：2016-02-04
申请号：AU2014295101
申请日：2014-07-22
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , WALMSLEY CLAIRE , DODSWORTH MARK , MEISSNER JOHANNES W G , BROUGH PAUL , FEJES IMRE , TATAI JANOS , NYERGES MIKLOS , KOTSCHY ANDRAS , SZLAVIK ZOLTAN , GENESTE OLIVIER , LE TIRAN ARNAUD , LE DIGUARHER THIERRY , HENLIN JEAN-MICHEL , STARCK JEROME-BENOIT , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME
IPC: C07D401/14 , A61K31/4709 , A61K31/4725 , A61P35/00 , A61P37/00 , C07D401/10 , C07D405/14 , C07D409/14 , C07D471/04
Abstract: Compounds of formula (I): (I) wherein Het, R
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">
公开(公告)号：FR3008978A1
公开(公告)日：2015-01-30
申请号：FR1357277
申请日：2013-07-23
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： CASARA PATRICK , LE DIGUARHER THIERRY , HENLIN JEAN-MICHEL , STARCK JEROME-BENOIT , LE TIRAN ARNAUD , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , WALMSLEY CLAIRE , GRAHAM CHRISTOPHER JOHN , RAY STUART , MADDOX DANIEL , BEDFORD SIMON
IPC: C07D471/04 , A61K31/437 , A61P35/00 , C07D207/30 , C07D209/04 , C07D213/02 , C07D215/14
Abstract: Composés de formule (I) : dans laquelle Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2, T et W sont tels que définis dans la description.
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公开(公告)号：FR3008975A1
公开(公告)日：2015-01-30
申请号：FR1357258
申请日：2013-07-23
Applicant: SERVIER LAB , VERNALIS R & D LTD
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , FEJES IMRE , TATAI JANOS , NYERGES MIKLOS LASZLO , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , DURAND DIDIER
IPC: C07D401/10 , A61K31/4725 , A61P35/00 , A61P37/00 , C07D207/44 , C07D217/04 , C07D217/12
Abstract: Composés de formule (I) : dans laquelle A1, A2, Ra, Rb, Rc, Rd, R3, R4, R5 et T sont tels que définis dans la description.
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公开(公告)号：CA2919572A1
公开(公告)日：2015-01-29
申请号：CA2919572
申请日：2014-07-22
Applicant: VERNALIS R&D LTD , SERVIER LAB
Inventor： DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN , WALMSLEY CLAIRE , DODSWORTH MARK , MEISSNER JOHANNES W G , BROUGH PAUL , FEJES IMRE , TATAI JANOS , NYERGES MIKLOS , KOTSCHY ANDRAS , SZLAVIK ZOLTAN , GENESTE OLIVIER , LE TIRAN ARNAUD , LE DIGUARHER THIERRY , HENLIN JEAN-MICHEL , STARCK JEROME-BENOIT , GUILLOUZIC ANNE-FRANCOISE , DE NANTEUIL GUILLAUME
IPC: C07D401/14 , A61K31/4709 , A61K31/4725 , A61P35/00 , A61P37/00 , C07D401/10 , C07D405/14 , C07D409/14 , C07D471/04
Abstract: Compounds of formula (I): (I) wherein Het, R3, R4, R5, R7, R8, R9, T, p, p', q, and q' are as defined in the description are pro-apoptotic agents useful in the treatment of cancers and of auto-immune and immune system diseases.
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公开(公告)号：CA2918217A1
公开(公告)日：2015-01-29
申请号：CA2918217
申请日：2014-07-22
Applicant: SERVIER LAB , VERNALIS R&D LTD
Inventor： LE TIRAN ARNAUD , LE DIGUARHER THIERRY , STARCK JEROME-BENOIT , HENLIN JEAN-MICHEL , DE NANTEUIL GUILLAUME , GENESTE OLIVIER , DAVIDSON JAMES EDWARD PAUL , MURRAY JAMES BROOKE , CHEN I-JEN
IPC: C07D471/04 , A61K31/4709 , A61K31/4985 , A61P35/00 , A61P37/00 , C07D487/04 , C07D519/00
Abstract: Composés de formule (I) dans laquelle Ra, Rb, Rc, Rd, T, R3, R4, R5, X, Y et Het sont tels que définis dans la description. Médicaments.
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